Prof. Laura Palombi
Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni
Paolo II, 132, 84084-Fisciano, SA, Italy
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Academic Career Length
31Years (1996-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 October 2012 in Current Organic Chemistry
Journal Article
Molecules containing 3-substituted isobenzofuranones and isoindolinones skeletons are found in important bioactive compounds and in a number of natural products. As a consequence several synthetic strategies, both asymmetric and non-asymmetric, have been developed. Thus, this review focuses on the main synthetic approaches to obtain these classes of compounds, analysing the common features, the scope and the limitations and at the same time giving particular emphasis to the role of active methylene compounds.
21 January 2003 in The Journal of Organic Chemistry
Journal Article
Marta FerociMCMaria Antonietta Casadei
Maria Antonietta CasadeiMOMonica Orsini
Monica Orsini
Laura PalombiAIAchille Inesi
Achille Inesi
15 December 2015 in Beilstein Journal of Organic Chemistry
Journal Article
AMAntonio Massa
Antonio MassaMTMaximilian Tiffner
Maximilian Tiffner
FSFrancesco Scorzelli
Francesco Scorzelli
Laura PalombiRFRosanna Filosa
Rosanna Filosa
Antonio Massa +2
New bifunctional chiral ammonium salts were investigated in an asymmetric cascade synthesis of a key building block for a variety of biologically relevant isoindolinones. With this chiral compound in hand, the development of further transformations allowed for the synthesis of diverse derivatives of high pharmaceutical value, such as the Belliotti (S)-PD172938 and arylated analogues with hypnotic sedative activity, obtained in good overall total yield (50%) and high enantiomeric purity (95% ee). The synthetic routes developed herein are particularly convenient in comparison with the current methods available in literature and are particularly promising for large scale applications.
1 September 2008 in Tetrahedron: Asymmetry
Journal Article
ASArrigo Scettri
Arrigo Scettri
Antonio MassaLaura PalombiRVRosaria Villano
Rosaria Villano
Maria Rosaria Acocella1 August 2002 in Tetrahedron Letters
Journal Article
Marta FerociAGArmando Gennaro
Armando Gennaro
AIAchille Inesi
Achille Inesi
MOMonica Orsini
Monica Orsini
Laura Palombi9 August 2012 in European Journal of Organic Chemistry
Journal Article
CPCarmen Petronzi
Carmen Petronzi
SCSelene Collarile
Selene Collarile
GCGianluca Croce
Gianluca Croce
RFRosanna Filosa
Rosanna FilosaPCPaolo De Caprariis
Paolo De Caprariis
Antonio Massa +4
About Me
After her Bachelor in Chemistry (University of Rome "La Sapienza" Thesis: “Photochemical and Enzimatic Reactivity of 2-(2-Furyl)-1,3-Dicarbonyl Compounds") and her PhD in Chemical Sciences (University of Rome "La Sapienza" PhD Thesis: "New methodologies for stereoselective and enantioselective oxidations"), Palombi obtained a four-year researcher position at the University of L'Aquila, where she started investigations in the field of the Organic Electrosynthesis. In 2004, she was appointed as an assistant professor in Organic Chemistry at the University of Salerno, where she focused her research on the development of new methodologies for stereo- and enantio-selective bond-forming reactions. Since April 2020, she has been an associate professor in Organic Chemistry in the Department of Physical and Chemical Sciences at the University of L’Aquila.