Danan Gu

Dr. Danan Gu


Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2021 in China CDC Weekly
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Journal Article
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DGDanan Gu
Danan Gu
KAKirill Andreev
Kirill Andreev
MDMatthew E. Dupre
Matthew E. Dupre
The world’s population continues to grow, albeit at a slower pace. The decelerating growth is mainly attributable to fertility declines in a growing number of countries. However, there are substantial variations in the future trends of populations across regions and countries, with sub-Saharan African countries being projected to have most of the increase. Population momentum plays an important role in determining the future population growth in many countries and areas where fertility is in a rapid transition. With declines in fertility, the world’s population is unprecedentedly aging, and the numbers of households with smaller sizes are growing. International migration is also on the rise since the beginning of this century. The world’s population is also urbanizing due to increased internal rural to urban migration. Nevertheless, there are uncertainties in future population growth, not only because there are uncertainties in the future trends in fertility, mortality, and migration, but also because there are many other factors that could affect these trajectories. International consensus on climate change and ecosystem protections may trigger population control policies, and the ongoing pandemic is likely to have some impact on mortality, migration, or even fertility.

19 July 2017 in BMC Geriatrics
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Journal Article
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XZXufan Zhang
Xufan Zhang
MDMatthew E. Dupre
Matthew E. Dupre
LQLi Qiu
Li Qiu
WZWei Zhou
Wei Zhou
YZYuan Zhao
Yuan Zhao
DGDanan Gu
Danan Gu
Studies have shown that inadequate access to healthcare is associated with lower levels of health and well-being in older adults. Studies have also shown significant urban-rural differences in access to healthcare in developing countries such as China. However, there is limited evidence of whether the association between access to healthcare and health outcomes differs by urban-rural residence at older ages in China. Four waves of data (2005, 2008/2009, 2011/2012, and 2014) from the largest national longitudinal survey of adults aged 65 and older in mainland China (n = 26,604) were used for analysis. The association between inadequate access to healthcare (y/n) and multiple health outcomes were examined—including instrumental activities of daily living (IADL) disability, ADL disability, cognitive impairment, and all-cause mortality. A series of multivariate models were used to obtain robust estimates and to account for various covariates associated with access to healthcare and/or health outcomes. All models were stratified by urban-rural residence. Inadequate access to healthcare was significantly higher among older adults in rural areas than in urban areas (9.1% vs. 5.4%; p < 0.01). Results from multivariate models showed that inadequate access to healthcare was associated with significantly higher odds of IADL disability in older adults living in urban areas (odds ratio [OR] = 1.58–1.79) and rural areas (OR = 1.95–2.30) relative to their counterparts with adequate access to healthcare. In terms of ADL disability, we found significant increases in the odds of disability among rural older adults (OR = 1.89–3.05) but not among urban older adults. Inadequate access to healthcare was also associated with substantially higher odds of cognitive impairment in older adults from rural areas (OR = 2.37–3.19) compared with those in rural areas with adequate access to healthcare; however, no significant differences in cognitive impairment were found among older adults in urban areas. Finally, we found that inadequate access to healthcare increased overall mortality risks in older adults by 33–37% in urban areas and 28–29% in rural areas. However, the increased risk of mortality in urban areas was not significant after taking into account health behaviors and baseline health status. Inadequate access to healthcare was significantly associated with higher rates of disability, cognitive impairment, and all-cause mortality among older adults in China. The associations between access to healthcare and health outcomes were generally stronger among older adults in rural areas than in urban areas. Our findings underscore the importance of providing adequate access to healthcare for older adults—particularly for those living in rural areas in developing countries such as China.

4 February 2009 in The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences
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Journal Article
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DGDanan Gu
Danan Gu
MDMatthew E. Dupre
Matthew E. Dupre
JSJessica Sautter
Jessica Sautter
HZHaiyan Zhu
Haiyan Zhu
YLYuzhi Liu
Yuzhi Liu
ZYZeng Yi
Zeng Yi
This study investigates the factors associated with frailty and the association of frailty with mortality in a national sample of adults aged 65–109 in China. Using the 2002 wave of the Chinese Longitudinal Healthy Longevity Survey, we construct a frailty index (FI) based on 39 measures available in the data set. We use ordinal logistic regressions to examine the factors associated with the FI and use Weibull hazard regression to examine the association between frailty and 3-year mortality from 2002 to 2005. Age, sex, ethnicity, urban–rural residence, economic condition, religious involvement, and daily exercise are significantly associated with levels of frailty. Hazard analyses further reveal that the FI is a robust predictor of mortality at advanced ages and that the relationship between frailty and mortality is independent of various covariates. The measurement and analysis of frailty have broad implications for public health initiatives designed to target individuals with the diminished capacity to effectively compensate for external stressors and to prevent further declines associated with aging and mortality. A key to healthy longevity is the prevention, postponement, and potential recovery from physical and cognitive deficits at advanced ages through enhanced medical interventions and treatments.

1 May 2010 in SLEEP
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Journal Article
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DGDanan Gu
Danan Gu
JSJessica Sautter
Jessica Sautter
RPRobin Pipkin
Robin Pipkin
YZYi Zeng
Yi Zeng
To examine factors associated with self-reported sleep quality and duration among very old adults in China. Cross-sectional analysis of the 2005 wave of the Chinese Longitudinal Healthy Longevity Survey (CLHLS). In-home interview with older adults in 22 provinces in mainland China. A total of 15,638 individuals aged 65 and older (5,047 aged 65–79, 3,870 aged 80–89, 3,927 aged 90–99, and 2,794 aged 100 and older, including 6,688 men and 8,950 women). N/A Two self-reported sleep questions together with numerous sociodemographic and health status measures were used in this study. Sixty-five per cent of Chinese elders reported good quality of sleep. The average number of self-reported hours of sleep was 7.5 (SD 1.9), with 13.1%, 16.2%, 18.0%, 28.0%, 9.2%, and 15.5% reporting ≤ 5, 6, 7, 8, 9, and ≥ 10 hours, respectively (weighted). Multivariate analyses showed that male gender, rural residence, Han ethnicity, higher socioeconomic status, and good health conditions were positively associated with good quality of sleep. All other factors being equal, octogenarians, nonagenarians, and centenarians were more likely to have good sleep quality than the young elders aged 65–79. Elders with poorer health status or older age were more likely to have either relatively shorter (≤ 6 h) or longer (≥ 10 h) sleep duration. Married elders were more likely to have an average duration between these two values. Except for some geographic variations, associations between all other factors and sleep duration were weak compared to the effects of health. Age and health conditions are the two most important factors associated with self-reported sleep quality and duration. Good quality of sleep among long-lived old adults may have some implications for achieving healthy longevity.

1 January 2009 in Social Science & Medicine
Verified
Journal Article
Closed access
DGDanan Gu
Danan Gu
ZZZhenmei Zhang
Zhenmei Zhang
YZYi Zeng
Yi Zeng

9 April 2020 in BMC Geriatrics
Verified
Journal Article
Open access
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LHLisha Hao
Lisha Hao
Xin XuXin Xu
Xin Xu
MDMatthew Dupre
Matthew Dupre
AGAimei Guo
Aimei Guo
XZXufan Zhang
Xufan Zhang
DGDanan Gu
Danan Gu
Background: Adequate access to healthcare is associated with lower risks of mortality at older ages. However, it is largely unknown how many more years of life can be attributed to having adequate access to healthcare compared with having inadequate access to healthcare. Method: A nationwide longitudinal survey of 27,794 older adults aged 65+ in mainland China from 2002 to 2014 was used for analysis. Multivariate hazard models and life table techniques were used to estimate differences in life expectancy associated with self-reported access to healthcare (adequate vs. inadequate). The findings were assessed after adjusting for a wide range of demographic factors, socioeconomic status, family/social support, health practices, and health conditions. Results: At age 65, adequate access to healthcare increased life expectancy by approximately 2.0–2.5 years in men and women and across urban-rural areas compared with those who reported inadequate access to healthcare. At age 85, the corresponding increase in life expectancy was 1.0–1.2 years. After adjustment for multiple confounding factors, the increase in life expectancy was reduced to approximately 1.1–1.5 years at age 65 and 0.6–0.8 years at age 85. In women, the net increase in life expectancy attributable to adequate access to healthcare was 6 and 8% at ages 65 and 85, respectively. In men, the net increases in life expectancy were generally greater (10 and 14%) and consistent after covariate adjustments. In contrast, the increase in life expectancy was slightly lower in rural areas (2.0 years at age 65 and 1.0 years at age 85) than in urban areas (2.1 years at age 65 and 1.1 years age 85) when no confounding factors were taken into account. However, the increase in life expectancy was greater in rural areas (1.0 years at age 65 and 0.6 years at age 85) than in urban areas (0.4 years at age 65 and 0.2 years at age 85) after accounting for socioeconomic and other factors. Conclusions: Adequate access to healthcare was associated with longer life expectancy among older adults in China. These findings have important implications for efforts to improve access to healthcare among older populations in China.