Various novel amine solutions both in aqueous and non-aqueous [monoethylene glycol (MEG)/triethylene glycol(TEG)] forms have been studied for hydrogen sulfide (H₂S) absorption. The study was conducted in a custom build experimental setup at temperatures relevant to subsea operation conditions and atmospheric pressure. Liquid phase absorbed H₂S, and amine concentrations were measured analytically to calculate H₂S loading (mole of H₂S/mole of amine). Maximum achieved H₂S loadings as the function of pKa, gas partial pressure, temperature and amine concentration are presented. Effects of solvent type on absorbed H₂S have also been discussed. Several new solvents showed higher H₂S loading as compared to aqueous N-Methyldiethanolamine (MDEA) solution which is the current industrial benchmark compound for selective H₂S removal in natural gas sweetening process.