Purpose: Over the past few decades, higher education institutions (HEIs) have become key players in regional economic development and knowledge transfer, which has led to a third mission for HEIs and the entrepreneurial university. The purpose of this paper is to assess the challenges of HEIs in fulfilling the third mission for economic development and the changing role of being an entrepreneurial university, and the changes that need to be implemented to fulfill this new mission. Design/methodology/approach: The authors have drawn on current literature to examine academic entrepreneurism and the entrepreneurial university, and how universities are fulfilling their third mission. Findings: The findings from our review of the literature demonstrated the varied economic and social benefit of universities conducting external third mission/entrepreneurial activities in the community, as well as how the changing role and expectations of universities to become more entrepreneurial, has not only changed the expectations and role of university administrators, faculty and staff but also the business community which they serve. The review also showed the varied challenges for universities in fulfilling the third mission of economic development. Research limitations/implications: Although ample literature and cases about universities’ third mission of economic development and the new entrepreneurial university (especially with research universities) were available, literature or research was limited on the specific challenges and obstacles faced by administrators, faculty and departments in fulfilling this mission, and few studies recommended changes that needed to be implemented in HEIs to support this new mission. Practical/implications: The paper supports the potential role that HEIs play in implementing economic development in their communities or region. The paper also highlights some of the necessary resources and policy changes that policymakers and university administrators need to implement to reward and recognize faculty in conducting outreach activities as part of the university’s third mission. Originality/value: The findings from this study highlight the challenges and barriers for faculty, staff and HEIs in fulfilling the third mission and becoming an entrepreneurial university.

An unpredictable shock hit the Italian economy in February 2020 when the spread of the COVID-19 virus began in Italy and other countries worldwide. In this context, Industry 4.0 (I4.0) technologies can be a fundamental tool for economic recovery by favouring the shift towards sustainable manufacturing. Therefore, it is necessary to measure the readiness of countries for I4.0 in order to guide policies in defining incentives to promote I4.0 and unlock its potential in the pandemic era. In this context, the paper aims to understand the readiness and responsiveness of the Italian Regions with respect to I4.0 concepts prior to the pandemic and identify best practices that are supporting companies in I4.0 adoption, with a focus on those incentivizing sustainable practices. An assessment framework before the pandemic is provided based on two dimensions: the readiness of firms to invest in I4.0 and favourable structural conditions. The assessment shows a group of alert regions as opposed to a group of unprepared, mostly linked Northern and Southern differences. Assuming that the “alert regions” are more likely to effectively manage and overcome the post- COVID-19 crisis, we provide a picture of how the Italian Regions have sought to encourage the adoption of digital technologies to improve resilience after the shock. The analysis shows that supporting measures mainly address Small and Medium-sized Enterprises. Furthermore, the tenders encouraging the adoption of I4.0 suggest that collaboration among stakeholders will become imperative.

This paper delves into the growing need for collaborative technological solutions to address environmental challenges, with a focus on the underexplored potential of Industry 4.0 technologies, in particular as regards blockchain technology (BCT) in small and medium-sized enterprises (SMEs). Recognizing the obstacles faced by SMEs when embracing green and digital transformation, this research aims to investigate how innovation intermediaries are able to unlock the collaborative potential of BCT for SMEs so as to enhance their environmental sustainability. When assessing and analysing the role of innovation intermediaries, we have also considered their interconnections and interactions with other actors: universities, government institutions and firms (the so-called “stakeholders”). Our research is based on a multiple case study of a still largely unexplored intermediary in the European context, the digital innovation hub (DIH), which extends the applicability of the technological innovation system framework. This approach contributes to research both on innovation intermediaries and on the development of collaborative partnerships for digitalization. The findings reveal the challenges encountered by DIHs, particularly in legitimizing BCT-based solutions. To address these, identified, weaknesses, the paper proposes a conceptual roadmap aimed at improving collaboration among DIHs, SMEs, and their stakeholders. This roadmap outlines three essential functions: enabling, core, and facilitating effective partnerships and innovation processes.

Ongoing global climate change, growing population and the intensification of economic activities, increase pressure on water resources, a situation many see as a water governance crisis. Water-related issues are becoming a limiting factor for sustainable economic growth and require a collaborative and interdisciplinary approach, to foster innovative solutions. This paper provides an evidence-based contribution to understanding Triple Helix Model (THM) relations and the path to innovation policy in the water sector. The analysis focuses on the interaction between university–industry–government, with specific reference to the Murcia region in Southeast Spain. This region combines a chronic shortage of water and a leading role for agriculture. Starting from the experience of a researcher, working for the General Water Council of the Murcia Region, this paper is based on both desk research and in-depth personal interviews with representatives of THM actors. In addition, a questionnaire was forwarded to all those companies in charge of providing water services in the Murcia region. The study has found that stakeholders are not fully cooperative in seeking innovation. The main challenges are the renewal of water-related facilities and the improvement of remote control systems, denitrification and desalination technologies and achieving better energy efficiency. To this aim, THM approach is suggested as a source of local innovation policies, identifying a series of tools to foster a collaborative approach.