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Ms. Daniela Debone
Federal University of São Paulo

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0 Regression Analysis
0 Climate change adaptation and mitigation
0 Air pollution and health
0 Machine and Deep Learning
0 Climate change and human health impacts

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Air pollution and health
Climate change adaptation and mitigation
Climate change and human health impacts

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Review
Published: 28 April 2021 in Urban Climate
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Understanding the major driving forces of CO2 emissions has become indispensable as the challenges of climate change and adaptation become more widely recognized. This systematic review presents a comprehensive overview of the econometric models applied to disentangling the relationships among carbon emissions, energy consumption, and economic growth. The electronic databases Web of Science, SCOPUS, and EconPapers were used to identify 776 citation records to discuss this issue. Resultantly, 182 peer-reviewed journal articles met the pre-defined eligibility criteria and were retained for discussion. We found varied modelling approaches, but artificial neural networks, STIRPAT model, and Granger causality were the primary models used by authors in recent years. Overall, the analyzed methods could be considered efficient in investigating the relationships between the analyzed variables, promoting discussion about the urgency of investment in renewable energy sources, and implementing appropriate CO2 emissions mitigation policies.

ACS Style

Daniela Debone; Vinicius Pazini Leite; Simone Georges El Khouri Miraglia. Modelling approach for carbon emissions, energy consumption and economic growth: A systematic review. Urban Climate 2021, 37, 100849 .

AMA Style

Daniela Debone, Vinicius Pazini Leite, Simone Georges El Khouri Miraglia. Modelling approach for carbon emissions, energy consumption and economic growth: A systematic review. Urban Climate. 2021; 37 ():100849.

Chicago/Turabian Style

Daniela Debone; Vinicius Pazini Leite; Simone Georges El Khouri Miraglia. 2021. "Modelling approach for carbon emissions, energy consumption and economic growth: A systematic review." Urban Climate 37, no. : 100849.

Journal article
Published: 10 September 2020 in Sustainability
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The COVID-19 pandemic has imposed a unique situation for humanity, reaching up to 5623 deaths in Sao Paulo city during the analyzed period of this study. Due to the measures for social distancing, an improvement of air quality was observed worldwide. In view of this scenario, we investigated the air quality improvement related to PM10, PM2.5, and NO2 concentrations during 90 days of quarantine compared to an equivalent period in 2019. We found a significant drop in air pollution of 45% of PM10, 46% of PM2.5, and 58% of NO2, and using a relative-risk function, we estimated that this significant air quality improvement avoided, respectively, 78, 337, and 387 premature deaths, respectively, and prevented approximately US$ 720 million on health costs. Moreover, we estimated that 5,623 deaths by COVID-19 represent an economic health loss of US$ 10.5 billion. Both health and economic gains associated with air pollution reductions give a positive perspective of the efforts towards keeping air pollution reduced even after the pandemic, highlighting the importance of improving the strategies of air pollution mitigation actions, as well as the crucial role of adopting efficient measures to protect human health both during and after the COVID-19 global health crisis.

ACS Style

Daniela Debone; Mariana Da Costa; Simone Miraglia. 90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil. Sustainability 2020, 12, 7440 .

AMA Style

Daniela Debone, Mariana Da Costa, Simone Miraglia. 90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil. Sustainability. 2020; 12 (18):7440.

Chicago/Turabian Style

Daniela Debone; Mariana Da Costa; Simone Miraglia. 2020. "90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil." Sustainability 12, no. 18: 7440.

Journal article
Published: 28 August 2020 in Urban Climate
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The frequent diesel oil price adjustments and the cost of freight are among the main reasons for Brazilian truckers' strike that occurred in 2018. This event showed the strong influence of the road transport sector in the economy and air quality on different urban centers of Sao Paulo. Air pollutants concentrations were compared during the strike days and control days, considering equivalent meteorological conditions on regions near to highways. Based on pollution reduction results, we calculated the relative risk and avoided deaths attributed to each pollutant analyzed. Economic impacts were evaluated using the Value of Statistical Life. The assays indicated that air pollutant concentrations were significantly reduced in all analyzed highways. The analyzed stretches of roads showed that associated health impacts were about 1.15 and 3.05 avoided deaths due to reductions of PM10 and NO2, respectively, which represent an economy of almost US$ 8 million during the strike. Estimates for a whole year scenario results in 81 (PM10) and 227 (NO2) potential avoided deaths, considering the reductions achieved during the strike, equivalent to a monetary gain of approximately US$ 579 million annually. Our findings provided evidence to support cleaner transportation investments and air quality mitigation actions.

ACS Style

Daniela Debone; Luciana Ferreira Leite Leirião; Simone Georges El Khouri Miraglia. Air quality and health impact assessment of a truckers' strike in Sao Paulo state, Brazil: A case study. Urban Climate 2020, 34, 100687 .

AMA Style

Daniela Debone, Luciana Ferreira Leite Leirião, Simone Georges El Khouri Miraglia. Air quality and health impact assessment of a truckers' strike in Sao Paulo state, Brazil: A case study. Urban Climate. 2020; 34 ():100687.

Chicago/Turabian Style

Daniela Debone; Luciana Ferreira Leite Leirião; Simone Georges El Khouri Miraglia. 2020. "Air quality and health impact assessment of a truckers' strike in Sao Paulo state, Brazil: A case study." Urban Climate 34, no. : 100687.

Preprint
Published: 02 August 2020
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The coronavirus disease (COVID-19) pandemic caused by spreading rapidly a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has imposed a unique situation for the humanity. Sao Paulo has reported 124,105 confirmed cases of COVID-19 and 5,623 deaths up to June 14th, being considered the epicenter of the pandemic in Brazil and in South America. Due to the measures for social distancing, there was a drop in the air pollution concentration in Sao Paulo. Starting on March 16th, 2020, we broke 90 days of social distancing into 13 weeks and compared to an equivalent period in 2019. We investigated the air quality improvement during the quarantine period and compared the associated avoided deaths to COVID-19 burden deaths. Nitrogen dioxide (NO2) was the best indicator of air quality in the analyzed weeks, since its reduction reached 58 %. Our study showed that the 5,623 deaths occurred during the analyzed weeks of quarantine represents an economic health loss of US$ 10.5 billion. In opposite, we observed a significant air quality improvement due to pollutants concentrations’ reductions during the analyzed weeks. Considering PM10, PM2.5 and NO2, the decrease of concentration levels respectively avoided 78, 337 and 387 premature deaths and prevented up to US$ 1.5 billion on health costs. These results highlight the importance of continuing to enforce existing air pollution regulations and measures to protect human health both during and after COVID-19 pandemic.

ACS Style

Daniela Debone; Mariana Da Costa; Simone Miraglia. 90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil. 2020, 1 .

AMA Style

Daniela Debone, Mariana Da Costa, Simone Miraglia. 90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil. . 2020; ():1.

Chicago/Turabian Style

Daniela Debone; Mariana Da Costa; Simone Miraglia. 2020. "90 Days of COVID-19 Social Distancing and Its Impacts on Air Quality and Health in Sao Paulo, Brazil." , no. : 1.

Journal article
Published: 27 February 2020 in Atmospheric Pollution Research
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In 2018, a truck-driver strike in Sao Paulo, Brazil, provided conditions for conducting a real-world experiment on the relationship between vehicle emissions, air quality, and public health. During the strike, no truck traffic, a 40–70% bus-traffic reduction, and a reduction in auto traffic was observed. The objective of this study is to evaluate the effects of vehicle-traffic reduction on the air quality and public health in Sao Paulo by taking advantage of the truck-driver strike. The corresponding analysis was based on the comparison of the air quality (NOx (nitrogen oxides), PM10 (particle matter of diameter less than 10 μm), and O3 (ozone) concentrations) during the strike and that registered on days having similar meteorological conditions. A relative-risk function was used to associate the decrease in the PM10 concentration during the strike with avoided mortality. The results demonstrated that, on workdays, the reduction in vehicle traffic during the strike was responsible for a 29.4%–40.9% improvement in NOx air quality and 19.2%–21.4% in PM10 concentration. The reduction in the PM10 concentration resulted in the prevention of between six and eight deaths during the strike, which implies between 321 and 442 avoided deaths in a year. In terms of the O3 concentration, no difference was identified between strike days and the comparative ones. An analysis of different sites of the city revealed that the greatest air-quality improvement was observed near an arterial road and near a bus terminal. Air-quality improvement was also detected in a park that was distant from the main roads. The results of the study provide evidence for supporting cleaner transportation investments and traffic restriction policies.

ACS Style

Luciana Ferreira Leite Leirião; Daniela Debone; Theotonio Pauliquevis; Nilton Manuel Évora Do Rosário; Simone Georges El Khouri Miraglia. Environmental and public health effects of vehicle emissions in a large metropolis: Case study of a truck driver strike in Sao Paulo, Brazil. Atmospheric Pollution Research 2020, 11, 24 -31.

AMA Style

Luciana Ferreira Leite Leirião, Daniela Debone, Theotonio Pauliquevis, Nilton Manuel Évora Do Rosário, Simone Georges El Khouri Miraglia. Environmental and public health effects of vehicle emissions in a large metropolis: Case study of a truck driver strike in Sao Paulo, Brazil. Atmospheric Pollution Research. 2020; 11 (6):24-31.

Chicago/Turabian Style

Luciana Ferreira Leite Leirião; Daniela Debone; Theotonio Pauliquevis; Nilton Manuel Évora Do Rosário; Simone Georges El Khouri Miraglia. 2020. "Environmental and public health effects of vehicle emissions in a large metropolis: Case study of a truck driver strike in Sao Paulo, Brazil." Atmospheric Pollution Research 11, no. 6: 24-31.

Research article
Published: 04 December 2019 in Journal of Immunology Research
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The severity of Plasmodium falciparum malaria is associated with parasite cytoadherence, but there is limited knowledge about the effect of parasite cytoadherence in malaria-associated acute respiratory distress syndrome (ARDS). Our objective was to evaluate the cytoadherence of infected red blood cells (iRBCs) in a murine model of ARDS and to appraise a potential function of endothelial protein C receptor (EPCR) in ARDS pathogenesis. DBA/2 mice infected with P. berghei ANKA were classified as ARDS- or hyperparasitemia- (HP-) developing mice according to respiratory parameters and parasitemia. Lungs, blood, and bronchoalveolar lavage were collected for gene expression or protein analyses. Primary cultures of microvascular lung endothelial cells from DBA/2 mice were analyzed for iRBC interactions. Lungs from ARDS-developing mice showed evidence of iRBC accumulation along with an increase in EPCR and TNF concentrations. Furthermore, TNF increased iRBC adherence in vitro. Dexamethasone-treated infected mice showed low levels of TNF and EPCR mRNA expression and, finally, decreased vascular permeability, thus protecting mice from ARDS. In conclusion, we identified that increased iRBC cytoadherence in the lungs underlies malaria-associated ARDS in DBA/2-infected mice and that inflammation increased cytoadherence capacity, suggesting a participation of EPCR and a conceivable target for drug development.

ACS Style

Luana Dos Santos Ortolan; Michelle Klein Sercundes; Gabriel Moura; Thatyane De Castro Quirino; Daniela Debone; Douglas De Sousa Costa; Oscar Murillo; Claudio Romero Farias Marinho; Sabrina Epiphanio. Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome. Journal of Immunology Research 2019, 2019, 1 -18.

AMA Style

Luana Dos Santos Ortolan, Michelle Klein Sercundes, Gabriel Moura, Thatyane De Castro Quirino, Daniela Debone, Douglas De Sousa Costa, Oscar Murillo, Claudio Romero Farias Marinho, Sabrina Epiphanio. Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome. Journal of Immunology Research. 2019; 2019 ():1-18.

Chicago/Turabian Style

Luana Dos Santos Ortolan; Michelle Klein Sercundes; Gabriel Moura; Thatyane De Castro Quirino; Daniela Debone; Douglas De Sousa Costa; Oscar Murillo; Claudio Romero Farias Marinho; Sabrina Epiphanio. 2019. "Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome." Journal of Immunology Research 2019, no. : 1-18.

Preprint
Published: 15 June 2018
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The severity of Plasmodium falciparum malaria is associated with parasite cytoadherence, but there is limited knowledge about the effect of parasite cytoadherence in malaria-associated acute respiratory distress syndrome (ARDS). Our objective was to evaluate the cytoadherence of infected red blood cells (iRBCs) in a murine model of ARDS and to appraise a potential function of endothelial protein C receptor (EPCR) in ARDS pathogenesis. DBA/2 mice infected with P. berghei ANKA were classified as ARDS- or hyperparasitemia (HP)-developing mice according to respiratory parameters and parasitemia. Lungs, blood and bronchoalveolar lavage were collected for gene expression or protein analyses. Primary cultures of microvascular lung endothelial cells from DBA/2 mice were analyzed for iRBC interactions. Lungs from ARDS-developing mice showed evidence of iRBC accumulation along with an increase in EPCR and TNF concentrations. Furthermore, TNF increased iRBC adherence in vitro. Dexamethasone-treated infected mice showed low levels of TNF and EPCR mRNA expression and, finally, decreased vascular permeability, thus protecting mice from ARDS. In conclusion, we identified that increased iRBC cytoadherence in the lungs underlies malaria-associated ARDS in DBA/2-infected mice and that inflammation increased cytoadherence capacity, suggesting a participation of EPCR and a conceivable target for drug development.

ACS Style

Luana Dos Santos Ortolan; Michelle Klein Sercundes; Gabriel Candido Moura; Thatyane De Castro Quirino; Daniela Debone; Douglas De Sousa Costa; Oscar Murillo; Claudio Romero Farias Marinho; Sabrina Epiphanio. Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome. 2018, 348318 .

AMA Style

Luana Dos Santos Ortolan, Michelle Klein Sercundes, Gabriel Candido Moura, Thatyane De Castro Quirino, Daniela Debone, Douglas De Sousa Costa, Oscar Murillo, Claudio Romero Farias Marinho, Sabrina Epiphanio. Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome. . 2018; ():348318.

Chicago/Turabian Style

Luana Dos Santos Ortolan; Michelle Klein Sercundes; Gabriel Candido Moura; Thatyane De Castro Quirino; Daniela Debone; Douglas De Sousa Costa; Oscar Murillo; Claudio Romero Farias Marinho; Sabrina Epiphanio. 2018. "Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome." , no. : 348318.

Published erratum
Published: 15 November 2017 in PLOS Pathogens
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[This corrects the article DOI: 10.1371/journal.ppat.1006054.].

ACS Style

Michelle K. Sercundes; Luana S. Ortolan; Daniela Debone; Paulo V. Soeiro-Pereira; Eliane Gomes; Elizabeth H. Aitken; Antonio Condino-Neto; Momtchilo Russo; Maria R. D' Império Lima; José M. Alvarez; Silvia Portugal; Claudio R. F. Marinho; Sabrina Epiphanio. Correction: Targeting Neutrophils to Prevent Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome in Mice. PLOS Pathogens 2017, 13, e1006730 .

AMA Style

Michelle K. Sercundes, Luana S. Ortolan, Daniela Debone, Paulo V. Soeiro-Pereira, Eliane Gomes, Elizabeth H. Aitken, Antonio Condino-Neto, Momtchilo Russo, Maria R. D' Império Lima, José M. Alvarez, Silvia Portugal, Claudio R. F. Marinho, Sabrina Epiphanio. Correction: Targeting Neutrophils to Prevent Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome in Mice. PLOS Pathogens. 2017; 13 (11):e1006730.

Chicago/Turabian Style

Michelle K. Sercundes; Luana S. Ortolan; Daniela Debone; Paulo V. Soeiro-Pereira; Eliane Gomes; Elizabeth H. Aitken; Antonio Condino-Neto; Momtchilo Russo; Maria R. D' Império Lima; José M. Alvarez; Silvia Portugal; Claudio R. F. Marinho; Sabrina Epiphanio. 2017. "Correction: Targeting Neutrophils to Prevent Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome in Mice." PLOS Pathogens 13, no. 11: e1006730.

Research article
Published: 07 December 2016 in PLOS Pathogens
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Malaria remains one of the greatest burdens to global health, causing nearly 500,000 deaths in 2014. When manifesting in the lungs, severe malaria causes acute lung injury/acute respiratory distress syndrome (ALI/ARDS). We have previously shown that a proportion of DBA/2 mice infected with Plasmodium berghei ANKA (PbA) develop ALI/ARDS and that these mice recapitulate various aspects of the human syndrome, such as pulmonary edema, hemorrhaging, pleural effusion and hypoxemia. Herein, we investigated the role of neutrophils in the pathogenesis of malaria-associated ALI/ARDS. Mice developing ALI/ARDS showed greater neutrophil accumulation in the lungs compared with mice that did not develop pulmonary complications. In addition, mice with ALI/ARDS produced more neutrophil-attracting chemokines, myeloperoxidase and reactive oxygen species. We also observed that the parasites Plasmodium falciparum and PbA induced the formation of neutrophil extracellular traps (NETs) ex vivo, which were associated with inflammation and tissue injury. The depletion of neutrophils, treatment with AMD3100 (a CXCR4 antagonist), Pulmozyme (human recombinant DNase) or Sivelestat (inhibitor of neutrophil elastase) decreased the development of malaria-associated ALI/ARDS and significantly increased mouse survival. This study implicates neutrophils and NETs in the genesis of experimentally induced malaria-associated ALI/ARDS and proposes a new therapeutic approach to improve the prognosis of severe malaria. A deeper understanding of the pathogenesis of malaria-associated ALI/ARDS may help in the development of new therapeutic approaches to improve the prognosis of severe cases of malaria. Using the Plasmodium berghei ANKA-infection mouse model of ALI/ARDS, which resembles the human disease in many aspects, this study reports the critical role of neutrophils in the pathogenesis of this syndrome. Mice developing ALI/ARDS showed abundant lung-infiltrating neutrophils in association with the increased production of neutrophil-attracting chemokines, myeloperoxidase and reactive oxygen species. The parasites Plasmodium falciparum and P. berghei ANKA both induced the formation of neutrophil extracellular traps ex vivo. By targeting neutrophils and neutrophil extracellular traps with specific drugs, we succeeded in preventing the development of malaria-associated ALI/ARDS and significantly increased mouse survival.

ACS Style

Michelle K. Sercundes; Luana S. Ortolan; Daniela Debone; Paulo V. Soeiro-Pereira; Eliane Gomes; Elizabeth H. Aitken; Antonio Condino-Neto; Momtchilo Russo; Maria Regina D'império Lima; José M. Alvarez; Silvia Portugal; Claudio R. F. Marinho; Sabrina Epiphanio. Targeting Neutrophils to Prevent Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome in Mice. PLOS Pathogens 2016, 12, e1006054 .

AMA Style

Michelle K. Sercundes, Luana S. Ortolan, Daniela Debone, Paulo V. Soeiro-Pereira, Eliane Gomes, Elizabeth H. Aitken, Antonio Condino-Neto, Momtchilo Russo, Maria Regina D'império Lima, José M. Alvarez, Silvia Portugal, Claudio R. F. Marinho, Sabrina Epiphanio. Targeting Neutrophils to Prevent Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome in Mice. PLOS Pathogens. 2016; 12 (12):e1006054.

Chicago/Turabian Style

Michelle K. Sercundes; Luana S. Ortolan; Daniela Debone; Paulo V. Soeiro-Pereira; Eliane Gomes; Elizabeth H. Aitken; Antonio Condino-Neto; Momtchilo Russo; Maria Regina D'império Lima; José M. Alvarez; Silvia Portugal; Claudio R. F. Marinho; Sabrina Epiphanio. 2016. "Targeting Neutrophils to Prevent Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome in Mice." PLOS Pathogens 12, no. 12: e1006054.

Research article
Published: 15 November 2016 in Mediators of Inflammation
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Malaria is a serious disease, caused by the parasite of the genusPlasmodium, which was responsible for 440,000 deaths in 2015. Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is one of the main clinical complications in severe malaria. The murine model DBA/2 reproduces the clinical signs of ALI/ARDS in humans, when infected withPlasmodium bergheiANKA. High levels of HO-1 were reported in cases of severe malaria. Our data indicated that the HO-1 mRNA and protein expression are increased in mice that develop malaria-associated ALI/ARDS (MA-ALI/ARDS). Additionally, the hemin, a HO-1 inducing drug, prevented mice from developing MA-ALI/ARDS when administered prior to the development of MA-ALI/ARDS in this model. Also, hemin treatment showed an amelioration of respiratory parameters in mice, high VEGF levels in the sera, and a decrease in vascular permeability in the lung, which are signs of ALI/ARDS. Therefore, the induction of HO-1 before the development of MA-ALI/ARDS could be protective. However, the increased expression of HO-1 on the onset of MA-ALI/ARDS development may represent an effort to revert the phenotype of this syndrome by the host. We therefore confirm that HO-1 inducing drugs could be used for prevention of MA-ALI/ARDS in humans.

ACS Style

Marcelo Pereira; Luana Dos Santos Ortolan; Michelle K. Sercundes; Daniela Debone; Oscar Murillo; Flavia Afonso Lima; Claudio R. F. Marinho; Sabrina Epiphanio. Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS. Mediators of Inflammation 2016, 2016, 1 -12.

AMA Style

Marcelo Pereira, Luana Dos Santos Ortolan, Michelle K. Sercundes, Daniela Debone, Oscar Murillo, Flavia Afonso Lima, Claudio R. F. Marinho, Sabrina Epiphanio. Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS. Mediators of Inflammation. 2016; 2016 ():1-12.

Chicago/Turabian Style

Marcelo Pereira; Luana Dos Santos Ortolan; Michelle K. Sercundes; Daniela Debone; Oscar Murillo; Flavia Afonso Lima; Claudio R. F. Marinho; Sabrina Epiphanio. 2016. "Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS." Mediators of Inflammation 2016, no. : 1-12.

Research article
Published: 02 September 2014 in Mediators of Inflammation
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Malaria-associated acute lung injury/acute respiratory distress syndrome (ALI/ARDS) often results in morbidity and mortality. Murine models to study malaria-associated ALI/ARDS have been described; we still lack a method of distinguishing which mice will develop ALI/ARDS before death. This work aimed to characterize malaria-associated ALI/ARDS in a murine model and to demonstrate the first method to predict whether mice are suffering from ALI/ARDS before death. DBA/2 mice infected withPlasmodium bergheiANKA developing ALI/ARDS or hyperparasitemia (HP) were compared using histopathology, PaO2measurement, pulmonary X-ray, breathing capacity, lung permeability, and serum vascular endothelial growth factor (VEGF) levels according to either the day of death or the suggested predictive criteria. We proposed a model to predict malaria-associated ALI/ARDS using breathing patterns (enhanced pause and frequency respiration) and parasitemia as predictive criteria from mice whose cause of death was known to retrospectively diagnose the sacrificed mice as likely to die of ALI/ARDS as early as 7 days after infection. Using this method, we showed increased VEGF levels and increased lung permeability in mice predicted to die of ALI/ARDS. This proposed method for accurately identifying mice suffering from ALI/ARDS before death will enable the use of this model to study the pathogenesis of this disease.

ACS Style

Luana Dos Santos Ortolan; Michelle K. Sercundes; Renato Barboza; Daniela Debone; Oscar Murillo; Stefano C. F. Hagen; Momtchilo Russo; Maria Regina D'império Lima; José M. Alvarez; Marcos Amaku; Claudio Romero Farias Marinho; Sabrina Epiphanio. Predictive Criteria to Study the Pathogenesis of Malaria-Associated ALI/ARDS in Mice. Mediators of Inflammation 2014, 2014, 1 -12.

AMA Style

Luana Dos Santos Ortolan, Michelle K. Sercundes, Renato Barboza, Daniela Debone, Oscar Murillo, Stefano C. F. Hagen, Momtchilo Russo, Maria Regina D'império Lima, José M. Alvarez, Marcos Amaku, Claudio Romero Farias Marinho, Sabrina Epiphanio. Predictive Criteria to Study the Pathogenesis of Malaria-Associated ALI/ARDS in Mice. Mediators of Inflammation. 2014; 2014 ():1-12.

Chicago/Turabian Style

Luana Dos Santos Ortolan; Michelle K. Sercundes; Renato Barboza; Daniela Debone; Oscar Murillo; Stefano C. F. Hagen; Momtchilo Russo; Maria Regina D'império Lima; José M. Alvarez; Marcos Amaku; Claudio Romero Farias Marinho; Sabrina Epiphanio. 2014. "Predictive Criteria to Study the Pathogenesis of Malaria-Associated ALI/ARDS in Mice." Mediators of Inflammation 2014, no. : 1-12.