Marine AMBAR AKKAOUI

Dr. Marine AMBAR AKKAOUI

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
9 December 2020 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
MAMarine AMBAR AKKAOUI
Marine AMBAR AKKAOUI
MLMichel Lejoyeux
Michel Lejoyeux
MDMarie-Pia D’ortho
Marie-Pia D’ortho
Pierre A. GeoffroyPierre A. Geoffroy
Pierre A. Geoffroy
Chronic nightmares are very common in psychiatric disorders, affecting up to 70% of patients with personality or post-traumatic stress disorders. In other psychiatric disorders, the relationships with nightmares are poorly known. This review aimed to clarify the relationship between nightmares and both mood and psychotic disorders. We performed a systematic literature search using the PubMed, Cochrane Library and PsycINFO databases until December 2019, to identify studies of patients suffering from either a mood disorder or a psychotic disorder associated with nightmares. From the 1145 articles screened, 24 were retained, including 9 studies with patients with mood disorders, 11 studies with patients with psychotic disorders and 4 studies with either psychotic or mood disorders. Nightmares were more frequent in individuals with mood or psychotic disorders than in healthy controls (more than two-fold). Patients with frequent nightmares had higher suicidality scores and had more frequently a history of suicide attempt. The distress associated with nightmares, rather than the frequency of nightmares, was associated with the severity of the psychiatric disorder. Further studies assessing whether nightmare treatment not only improves patient–sleep perception but also improves underlying psychiatric diseases are needed. In conclusion, nightmares are overrepresented in mood and psychotic disorders, with the frequency associated with suicidal behaviors and the distress associated with the psychiatric disorder severity. These findings emphasize major clinical and therapeutic implications.

17 May 2022 in Scientific Reports
Verified
Journal Article
Open access
PDF file
MAMarine AMBAR AKKAOUI
Marine AMBAR AKKAOUI
CCChristine Chan-Chee
Christine Chan-Chee
KLKarine Laaidi
Karine Laaidi
GFGregory Fifre
Gregory Fifre
MLMichel Lejoyeux
Michel Lejoyeux
PGPierre A. Geoffroy
Pierre A. Geoffroy
The objective of this study was to examine the evolution of suicides and suicide attempts over the last 10 years in France. We analyzed the number of deaths by suicide and suicide attempts in metropolitan France (2009–2018) from French national databases, on a daily, weekly or monthly basis. Seasonal variation in suicide rates was modeled using a cosinor function. Based on this model, we determined the association of suicides and suicide attempts with geographic characteristics, age, gender, means used and psychiatric disorders. The number of suicides and suicide attempts decreased over the last ten years in France (mean decrease of 14.49% and 11.69% per year). We observed a significant and recurrent seasonal pattern of suicides and suicide attempts in France, with a peak in spring. The suicide and suicide attempt rates were higher in the northern departments of France. Suicides were more frequent for men (75%) and middle-age individuals (45–54 years old), while suicide attempts were more frequent for women (62%) and young adults and middle-age individual (15–19 and 40–49 years old). Nearly two-thirds of the patients who attempted suicide suffered from comorbid psychiatric disorders. Mood disorders was the most frequent comorbid psychiatric disorder (54%). Voluntary drug intoxication was the most common means of suicide attempt (80%), and hanging was the most common means of suicide (54%). The number of suicides and suicide attempts decreased in France over the last 10 years, with large and recurrent seasonal variations. These findings could be used to alert and adjust prevention policies, as well as developing preventive strategies such as chronotherapeutics.

30 August 2022 in European Journal of Epidemiology
Verified
Journal Article
Open access
PDF file
FJFabrice Jollant
Fabrice Jollant
IBIngrid Blanc-Brisset
Ingrid Blanc-Brisset
MCMorgane Cellier
Morgane Cellier
MAMarine AMBAR AKKAOUI
Marine AMBAR AKKAOUI
VTViet Chi Tran
Viet Chi Tran
DVDominique Vodovar
Dominique Vodovar
Concerns have been raised about early vs. later impacts of the COVID-19 pandemic on suicidal behavior. However, data remain sparse to date. We investigated all calls for intentional drug or other toxic ingestions to the eight Poison Control Centers in France between 1st January 2018 and 31st May 2022. Data were extracted from the French National Database of Poisonings. Calls during the study period were analyzed using time trends and time series analyses with SARIMA models (based on the first two years). Breakpoints were determined using Chow test. These analyses were performed together with examination of age groups (≤ 11, 12–24, 25–64, ≥ 65 years) and gender effects when possible. Over the studied period, 66,589 calls for suicide attempts were received. Overall, there was a downward trend from 2018, which slowed down in October 2019 and was followed by an increase from November 2020. Number of calls observed during the COVID period were above what was expected. However, important differences were found according to age and gender. The increase in calls from mid-2020 was particularly observed in young females, while middle-aged adults showed a persisting decrease. An increase in older-aged people was observed from mid-2019 and persisted during the pandemic. The pandemic may therefore have exacerbated a pre-existing fragile situation in adolescents and old-aged people. This study emphasizes the rapidly evolving situation regarding suicidal behaviour during the pandemic, the possibility of age and gender differences in impact, and the value of having access to real-time information to monitor suicidal acts.

15 January 2025 in International Journal of Emergency Medicine
Verified
Journal Article
Open access
PDF file
MAMarine AMBAR AKKAOUI
Marine AMBAR AKKAOUI
DBDavid Barruel
David Barruel
VMValérie Dauriac-Le Masson
Valérie Dauriac-Le Masson
RGRaphael Gourevitch
Raphael Gourevitch
APAlexandra Pham-Scottez
Alexandra Pham-Scottez
Psychiatric emergency departments (EDs) in France have been under pressure from several factors, exacerbated by the COVID-19 pandemic. The pandemic led to an increase in psychiatric disorders, particularly anxiety and depression, with younger people and women being most affected. The aim of this study was to provide a comprehensive description of the trends in the number of visits to the largest psychiatric emergency department in France, with a particular focus on the period preceding and following the advent of COVID-19 pandemic. This retrospective study analyzed data from 69,764 visits to the Centre Psychiatrique d’Orientation et d’Accueil (CPOA) in Paris from 2016 to 2023. Patient data, including demographics, reasons for visit, and diagnoses, were collected and analyzed to identify trends over this period. The study observed a 28.5% increase in ED visits from 2016 to 2023. The increase was primarily driven by mood and anxiety disorders, which showed increases of 38.6% and 75.4%, respectively. The average age of patients decreased, reflecting a younger population increasingly affected by psychiatric problems. Interestingly, despite the increase in ED visits, hospital admissions decreased by 11.9%, with a notable decrease in involuntary commitment. The findings highlight a paradox where increased psychiatric ED visits are not accompanied by an increase in hospital admissions. This suggests a shift toward outpatient care due to systemic factors, including reduced hospital bed availability and challenges in accessing timely outpatient services. This study underscores the need to strengthen outpatient mental health services to effectively manage the growing demand. Further research, especially multicenter studies, is recommended to validate these findings and inform policy changes.

8 December 2021 in Psychiatry and Clinical Neurosciences
Verified
Journal Article
Closed access
PDF file
MAMarine AMBAR AKKAOUI
Marine AMBAR AKKAOUI
MDMarie‐Pia D'Ortho
Marie‐Pia D'Ortho
RGRaphael Gourevitch
Raphael Gourevitch
APAlexandra Pham‐Scottez
Alexandra Pham‐Scottez
PBPatricia Benhamou
Patricia Benhamou
PGPierre A. Geoffroy
Pierre A. Geoffroy

2 June 2020 in Biological Psychiatry
Verified
Journal Article
Closed access
PDF file
MAMarine AMBAR AKKAOUI
Marine AMBAR AKKAOUI
MLMichel Lejoyeux
Michel Lejoyeux
PGPierre A. Geoffroy
Pierre A. Geoffroy