One of the severe and prolonged disorder of the human brain which disturbs the behavioral characteristics of an individual completely such as interruption in the thinking process and speech is schizophrenia. It is a manifestation of many symptoms such as hallucinations, functional deterioration, disorganized speech and hearing sounds and speeches that are non-existent. In this paper, a computerized approach based on optimization and classification is done to analyze the classification of schizophrenia from Electroencephalography (EEG) signals. As EEG can analyze a lot of brain disorders and is used to study the diseases of the brain in an in-depth manner, it can be used to analyze the schizophrenia EEG signals. In this paper, three feature extraction techniques are employed such as Partial Least Squares (PLS) Non linear Regression technique, Expectation Maximization based Principal Component Analysis (EM-PCA) technique and Isometric Mapping (Isomap) technique. The extracted features are further optimized with four optimization algorithms such as Flower Pollination algorithm, Eagle strategy using different evolution algorithm, Backtracking search optimization algorithm and Group search optimization algorithm. The optimized values are then classified with varied versions of both Adaboost classifier and Naïve Bayesian Classifier. The individual results show that for normal cases, Isomap features when optimized with Backtracking search optimization algorithm and classified with Modest Adaboost classifier, a classification accuracy of 98.77% is obtained. The individual results show that for schizophrenia case, when Isomap features are optimized with Flower Pollination optimization algorithm and classified with Real Adaboost classifier, a classification accuracy of 98.77% is obtained.

To unlock information present in clinical description, automatic medical text classification is highly useful in the arena of natural language processing (NLP). For medical text classification tasks, machine learning techniques seem to be quite effective; however, it requires extensive effort from human side, so that the labeled training data can be created. For clinical and translational research, a huge quantity of detailed patient information, such as disease status, lab tests, medication history, side effects, and treatment outcomes, has been collected in an electronic format, and it serves as a valuable data source for further analysis. Therefore, a huge quantity of detailed patient information is present in the medical text, and it is quite a huge challenge to process it efficiently. In this work, a medical text classification paradigm, using two novel deep learning architectures, is proposed to mitigate the human efforts. The first approach is that a quad channel hybrid long short‐term memory (QC‐LSTM) deep learning model is implemented utilizing four channels, and the second approach is that a hybrid bidirectional gated recurrent unit (BiGRU) deep learning model with multihead attention is developed and implemented successfully. The proposed methodology is validated on two medical text datasets, and a comprehensive analysis is conducted. The best results in terms of classification accuracy of 96.72% is obtained with the proposed QC‐LSTM deep learning model, and a classification accuracy of 95.76% is obtained with the proposed hybrid BiGRU deep learning model.

With the development of sensing technologies and machine learning, techniques that can identify emotions and inner states of a human through physiological signals, known as electroencephalography (EEG), have been actively developed and applied to various domains, such as automobiles, robotics, healthcare, and customer-support services. Thus, the demand for acquiring and analyzing EEG signals in real-time is increasing. In this paper, we aimed to acquire a new EEG dataset based on the discrete emotion theory, termed as WeDea ( W ireless-based e eg D ata for e motion a nalysis), and propose a new combination for WeDea analysis. For the collected WeDea dataset, we used video clips as emotional stimulants that were selected by 15 volunteers. Consequently, WeDea is a multi-way dataset measured while 30 subjects are watching the selected 79 video clips under five different emotional states using a convenient portable headset device. Furthermore, we designed a framework for recognizing human emotional state using this new database. The practical results for different types of emotions have proven that WeDea is a promising resource for emotion analysis and can be applied to the field of neuroscience.

One of the serious mental disorders where people interpret reality in an abnormal state is schizophrenia. A combination of extremely disordered thinking, delusion, and hallucination is caused due to schizophrenia, and the daily functions of a person are severely disturbed because of this disorder. A wide range of problems are caused due to schizophrenia such as disturbed thinking and behaviour. In the field of human neuroscience, the analysis of brain activity is quite an important research area. For general cognitive activity analysis, electroencephalography (EEG) signals are widely used as a low-resolution diagnosis tool. The EEG signals are a great boon to understand the abnormality of the brain disorders, especially schizophrenia. In this work, schizophrenia EEG signal classification is performed wherein, initially, features such as Detrend Fluctuation Analysis (DFA), Hurst Exponent, Recurrence Quantification Analysis (RQA), Sample Entropy, Fractal Dimension (FD), Kolmogorov Complexity, Hjorth exponent, Lempel Ziv Complexity (LZC), and Largest Lyapunov Exponent (LLE) are extracted initially. The extracted features are, then, optimized for selecting the best features through four types of optimization algorithms here such as Artificial Flora (AF) optimization, Glowworm Search (GS) optimization, Black Hole (BH) optimization, and Monkey Search (MS) optimization, and finally, it is classified through certain classifiers. The best results show that, for normal cases, a classification accuracy of 87.54% is obtained when BH optimization is utilized with Support Vector Machine-Radial Basis Function (SVM-RBF) kernel, and for schizophrenia cases, a classification accuracy of 92.17% is obtained when BH optimization is utilized with SVM-RBF kernel.

Ovarian Cancer is a type of cancer that begins in ovaries posing a serious threat to women. As a result, it leads to abnormal cells which has the ability to spread to other regions of the body. A highly useful diagnostic and prognostic data for ovarian cancer research is provided by the microarray data. Typically, genes with tens of thousands of dimension are present in the microarray data of ovarian cancer. There is a systematic methodology required to analyze this data and so it is important to select the most important genes or features for the entire data to avoid the computational complexity. In this work, an integrated approach to feature selection is done by two consecutive steps. Initially, the features are selected by the standard gene selection techniques such as Correlation Coefficient, T-Statistics and Kruskal-Wallis test. The selected genes or features will be further optimized by four suitable stochastic optimization algorithms chosen here such as Central Force Optimization (CFO), Lightning Attachment Procedure Optimization (LAPO), Genetic Bee Colony Optimization (GBCO) and Artificial Algae Optimization (AAO). Finally, it is classified with five different classifiers to analyze the ovarian cancer classification and the best results are projected when Kruskal Wallis test with GBCO is conducted and classified with Support Vector Machine - Radial Basis Function (SVM-RBF) Kernel technique giving a high classification accuracy of 99.48%. Similar results are also obtained when Correlation Coefficient test with AAO is conducted and classified with Logistic Regression giving a high classification accuracy of 99.48%.