Aoife Fleming

Dr. Aoife Fleming

School of Pharmacy, University College Cork, Cork, Ireland
orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 November 2014 in BMJ Open
Verified
Journal Article
Open access
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Aoife FlemingAoife Fleming
Aoife Fleming
CBColin Bradley
Colin Bradley
SCShane Cullinan
Shane Cullinan
SBStephen Byrne
Stephen Byrne
Objectives To explore healthcare professionals’ views of antibiotic prescribing in long-term care facilities (LTCFs). To use the findings to recommend intervention strategies for antimicrobial stewardship in LTCFs. Design Qualitative semistructured interviews were conducted. The data were analysed by thematic content analysis. After the interviews, the emerging findings were mapped to the theoretical domains framework (TDF), and the behaviour change wheel and behaviour change technique (BCT) taxonomy were used to recommend future intervention strategies. Participants Interviews were conducted with 37 healthcare professionals who work in LTCFs (10 general practitioners, 4 consultants, 14 nurses, 9 pharmacists) between December 2012 and March 2013. Setting Interviews were conducted in the greater Cork region. Results The main domains from the TDF which emerged were: ‘Knowledge’, ‘Environmental context and resources’, ‘Social influences’, ‘Beliefs about consequences’, ‘Memory, attention and decision making’, with the findings identifying a need for ‘Behavioural regulation’. Many participants believed that antibiotic prescribing was satisfactory at their LTCF, despite the lack of surveillance activities. Conclusions This study, using the TDF and BCT taxonomy, has found that antibiotic prescribing in LTCFs is influenced by many social and contextual factors. The challenges of the setting and patient population, the belief about consequences to the patient, and the lack of implementation of guidelines and knowledge regarding antibiotic prescribing patterns are significant challenges to address. On the basis of the study findings and the application of the TDF and BCT taxonomy, we suggest some practical intervention functions for antimicrobial stewardship in LTCFs.

13 June 2014 in Drugs & Aging
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Journal Article
Closed access
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SCShane Cullinan
Shane Cullinan
DODenis O’mahony
Denis O’mahony
Aoife FlemingAoife Fleming
Aoife Fleming
SBStephen Byrne
Stephen Byrne

18 November 2014 in British Journal of Clinical Pharmacology
Verified
Journal Article
Open access
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SCShane Cullinan
Shane Cullinan
Aoife FlemingAoife Fleming
Aoife Fleming
DODenis O'MAhony
Denis O'MAhony
CRCristin Ryan
Cristin Ryan
DODavid O'SUllivan
David O'SUllivan
SBStephen Byrne
Stephen Byrne
Aims: Older patients commonly suffer from multimorbidites and take multiple medications. As a result, these patients are more vulnerable to potentially inappropriate prescribing (PIP). PIP in older patients may result in adverse drug events (ADEs) and hospitalizations. However, little has been done to identify why PIP occurs. The objectives of this study were (i) to identify hospital doctors' perceptions as to why PIP occurs, (ii) to identify the barriers to addressing the issues identified and (iii) to determine which intervention types would be best suited to improving prescribing.Methods: Semi‐structured interviews based on the Theoretical Domains Framework (TDF), a tool used to apply behaviour change theories, were conducted with 22 hospital doctors. Content analysis was conducted to identify domains of the TDF that could be targeted to improve prescribing for older people. These domains were then mapped to the behaviour change wheel to identify possible intervention types.Results: Content analysis identified five of the 12 domains in the TDF as relevant: (i) environmental context and resources, (ii) knowledge, (iii) skills, (iv) social influences and (v) memory/attention and decision processes. Using the behaviour change wheel, the types of interventions deemed suitable were those based on training and environmental restructuring.Conclusion: This study shows that doctors feel there is insufficient emphasis on geriatric pharmacotherapy in their undergraduate/postgraduate training. An intervention providing supplementary training, with particular emphasis on decision processes and dealing with social influences would be justified. This study has, however, uncovered many areas for potential intervention in the future.


2 April 2015 in Drugs & Aging
Verified
Journal Article
Open access
PDF file
Aoife FlemingAoife Fleming
Aoife Fleming
CBColin Bradley
Colin Bradley
SCShane Cullinan
Shane Cullinan
SBStephen Byrne
Stephen Byrne
Objectives The objective of this review was to synthesize the findings of qualitative studies investigating the factors influencing antibiotic prescribing in long-term care facilities (LTCFs). These findings will inform the development of future antimicrobial stewardship strategies (AMS) in this setting. Methods We searched Embase, PubMed, PsycInfo, Social Science Citations Index and Google Scholar for all qualitative studies investigating health care professionals’ views on antibiotic prescribing in LTCFs. The quality of the papers was assessed using the Critical Appraisal Skills Programme (CASP) assessment tool for qualitative research. Thematic synthesis was used to integrate the emergent themes into an overall analytical theme. Results The synthesis of eight qualitative studies indicated that health care professionals and administrators have identified factors that influence antibiotic prescribing in LTCFs. These factors include variations in knowledge and practice among health care professionals, and the LTCF context, which is unique given the complex patient population and restricted access to doctors and diagnostic tests. The social factors underpinning the interaction between nurses, residents’ families and doctors also influence decision making around antibiotic prescribing. The study also found that there is an acknowledged need for collaborative, evidence-based AMS specific to LTCFs, as antibiotic prescribing is heavily influenced by factors unique to this setting. Conclusion This review highlighted the key contextual challenges for AMS in LTCFs. The findings provide an in-depth insight into the factors—such as the LTCF context, social factors, variability in knowledge and prescribing practices, and antimicrobial resistance—that impact on antibiotic prescribing and AMS strategies. These factors must be considered in order to ensure the feasibility and applicability of future AMS interventions.

1 April 2019 in Research in Social and Administrative Pharmacy
Verified
Journal Article
Closed access
SMS. Marshall
S. Marshall
Aoife FlemingAoife Fleming
Aoife Fleming
AMAnne Moore
Anne Moore
Laura SahmLaura Sahm
Laura Sahm