The objective of this study was to analyze the type and amount of food consumed at breakfast and its also contribution in daily nutrient intake of school children (6—12 years old). The data used for this study was the secondary data of the Basic Health Survey 2010 (Riskesdas 2010) conducted by the Research and Development Agency, Ministry of Health. The data of 24-hour recall of food consumption and socio-economic were obtained from 35 000 school age children. The results of the study shows that ten most populer food consumed during breakfast are rice, scramble egg, fried tempeh, vegetable soup, fried fish, instant noodle, fried rice, stir vegetable, and fried tofu; and the five most populer beverages consumed during breakfast are drinking water, sweetened tea, milk creamer, powder milk, and tea. Nearly half (44.6%) of the children breakfast with low nutritional quality. Approximately 44.6%, 35.4%, 67.8%, 85.0%, 89.4%, and 90.3% of child-ren consume only <15% RDI for energy, protein, vitamin A, iron, calcium, and fiber respectively. Based on these results and inline with one of the dietary guidelines messages – do breakfast everyday – the healthy breakfast for school children need further promoted intensively. It is suggested that the healthy breakfast should be able to fulfill 15—30% of daily nutrients requirements.Key words: breakfast, RISKESDAS 2010, school childrenABSTRAKTujuan penelitian ini adalah untuk menganalisis jumlah dan jenis makanan dan minuman sarapan serta kontribusinya dalam asupan gizi harian anak usia sekolah (6—12 tahun). Data yang digunakan untuk penelitian ini adalah data sekunder (data konsumsi pangan) yang diperoleh dari hasil penelitian Riset Kesehatan Dasar (Riskesdas) 2010 yang dilaksanakan oleh Badan Penelitian dan Pengembangan Kesehatan Kementerian Ke-sehatan Indonesia. Data konsumsi pangan (recall 24 jam) dan sosial ekonomi diperoleh dari 35 000 subjek anak usia sekolah (6—12 tahun). Hasil penelitian ini menunjukkan bahwa sepuluh makanan yang paling favorit dikonsumsi saat sarapan adalah nasi putih, telur ceplok/dadar, tempe goreng, sayur berkuah, ikan goreng, mi instan, nasi goreng, sayuran (tumis), dan tahu goreng; sedangkan lima minuman terpopuler yang dikonsumsi sebagai sarapan adalah air putih, teh manis, susu kental manis, susu instan, dan air teh. Hampir separuh (44.6%) anak usia sekolah sarapan dengan kualitas gizi rendah. Sekitar 44.6%, 35.4%, 67.8%, 85.0%, 89.4%, dan 90.3% anak hanya memperoleh gizi <15% AKG dari sarapan (berturut-turut untuk energi, protein, vitamin A, zat besi, kalsium, dan serat). Berdasarkan hasil tersebut dan juga sejalan dengan salah satu isi Pesan Dasar Umum Gizi Seimbang (PUGS), yaitu “Sarapan setiap hari”, maka promosi mengenai kebiasaan sarapan sehat bagi anak usia sekolah perlu dilakukan lebih intensif dan berkelanjutan. Selain itu disarankan pula bahwa sarapan yang sehat sebaiknya mampu memenuhi sekitar 15—30% AKG.Kata kunci: anak usia sekolah, RISKESDAS 2010, sarapan

This study evaluated the effects of an aqueous extract of Caulerpa racemosa (AEC) on cardiometabolic syndrome markers, and the modulation of the gut microbiome in mice administered a cholesterol- and fat-enriched diet (CFED). Four groups of mice received different treatments: normal diet, CFED, and CFED added with AEC extract at 65 and 130 mg/kg body weight (BW). The effective concentration (EC₅₀) values of AEC for 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and lipase inhibition were lower than those of the controls in vitro. In the mice model, the administration of high-dose AEC showed improved lipid and blood glucose profiles and a reduction in endothelial dysfunction markers (PRMT-1 and ADMA). Furthermore, a correlation between specific gut microbiomes and biomarkers associated with cardiometabolic diseases was also observed. In vitro studies highlighted the antioxidant properties of AEC, while in vivo data demonstrated that AEC plays a role in the management of cardiometabolic syndrome via regulation of oxidative stress, inflammation, endothelial function (PRMT-1/DDAH/ADMA pathway), and gut microbiota.

Diabetes and obesity are chronic diseases that are a burden to low- and middle-income countries. We conducted this systematic review to understand gene–diet interactions affecting the Southeast Asian population’s risk of obesity and diabetes. The literature search was performed on Google Scholar and MEDLINE (PubMed) search engines independently by four reviewers who evaluated the eligibility of articles based on inclusion criteria. Out of 19,031 articles, 20 articles examining gene–diet interactions on obesity and/or diabetes-related traits met the inclusion criteria. Three (Malaysia, Indonesia, and Singapore) out of eleven Association of Southeast Asian Nations (ASEAN) countries have conducted studies on gene–diet interactions on obesity and diabetes. From the 20 selected articles, the most common interactions were observed between macronutrients and genetic risk score (GRS) on metabolic disease-related traits in the Malay, Chinese, and Indian ethnicities. Overall, we identified 29 significant gene–diet interactions in the Southeast Asian population. The results of this systematic review demonstrate ethnic-specific gene–nutrient interactions on metabolic-disease-related traits in the Southeast Asian population. This is the first systematic review to explore gene–diet interactions on obesity and diabetes in the Southeast Asian population and further research using larger sample sizes is required for better understanding and framing nutrigenetic approaches for personalized nutrition.

The objective of this study was to analyze type, amount, and nutritional quality of breakfast among Indonesian children aged 3—12 years old. Data used for this study was secondary data of Basic Health Survey 2010 (Riskesdas 2010). Data was collected from June until August 2010 by applying a cross sectional design. This study covered 33 provinces of Indonesia, with total 40,437 children consisted of 20,659 boys and 19,778 girls. The results of this study showed that ten major type of foods consumed during breakfast were rice, swamp cabbage, egg, fish, tempe, instant noodles, tofu, bread, chicken and biscuits; and five major type of beverages consumed during breakfast were drinking water, tea, milk, coffee, and syrup. The food consumed on average of more than 5 g a day during breakfast were rice, swamp cabbage, egg, fish, tempe, instant noodles; and the beverages consumed on average of more than 15 mL a day were water, tea, and milk. Only 10.6% of children breakfast met energy intake>30% RDA.

Asthma remains a significant global health challenge, demanding innovative approaches to treatment. Traditional medicine has a rich history of using natural products to alleviate asthmatic symptoms. However, transitioning from these traditional remedies to modern drug discovery approaches has provided fresh insights into the mechanisms and effectiveness of these natural products. This study provides our comprehensive review, which examines the current state of knowledge in the treatment of asthma. It delves into the mechanisms through which natural products ameliorate asthma symptoms, and it discusses their potential in the development of novel therapeutic interventions. Our analysis reveals that natural products, traditionally employed for asthma relief, exhibit diverse mechanisms of action. These include anti-inflammatory, bronchodilatory, immunomodulatory effects, and reducing gene expression. In the context of modern drug discovery, these natural compounds serve as valuable candidates for the development of novel asthma therapies. The transition from traditional remedies to modern drug discovery represents a promising avenue for asthma treatment. Our review highlights the substantial efficacy of natural products in managing asthma symptoms, underpinned by well-defined mechanisms of action. By bridging the gap between traditional and contemporary approaches, we contribute to the growing body of knowledge in the field, emphasizing the potential of natural products in shaping the future of asthma therapy.

The application of probability method to estimate micronutrient deficiencies prevalence of Indonesian adults