Diagnosis of suicide risk is a clinical challenge requiring an interdisciplinary therapeutic approach. Except for psychological explanation of the suicidal mechanism, there is evidence that it is associated with brain chemistry disturbances as oxidative stress. The objective of this study was to explore the role of oxidative stress components in suicidality comparing subjects at different stages of suicide. The study included psychiatric inpatients aged 18–64 (n = 48) with different psychiatric diagnoses. Blood specimens were collected from subjects and tested for oxidative stress biomarkers: superoxide dismutase (SOD), dityrozine (DT), oxidative stress index (OSI), glutathione peroxidase (GPx), total antioxidant capacity (TAC trolox), ferric reducing ability of plasma (FRAP), total oxidant status (TOS), catalase (CAT), advanced glycoxidation end products (AGE), NADPH oxidase (NOX), and advanced oxidation protein products (AOPP). The Columbia Severity Suicide Scale (C-SSRS) was used for suicidality assessment. Subjects with a history of suicide ideations over the last three months had significantly higher levels of NOX, AOPP, and OSI. There was no significant relationship to any oxidative stress component levels either with a history of suicide behaviors or with suicide attempts over the last three months. The levels of NOX and AOPP were both positively correlated to the intensity of suicidal thoughts. Moreover, there was a positive correlation between a number of suicide attempts during a lifetime with AGE and DT and negative with CAT. Similarly, the subjects with a history of suicide attempts had significantly higher AGE and DT levels and lower CAT values. The study confirmed that oxidative stress plays an important role in the pathophysiology of suicide and specific oxidative stress measures vary in suicidal and non-suicidal psychiatric inpatients.

Background: From 1 January 2024, Poland legally banned the sale of energy drinks (EDs) containing caffeine and taurine to minors under 18. EDs are rich in stimulants, making them particularly popular among adolescents and young adults seeking energy boosts. Their consumption is associated with adverse health effects and engagement in risky behaviors. This descriptive snapshot study explores energy drink consumption, motivations, and risk perception among Polish adults. Methods: A cross-sectional, nationwide survey (N = 1121) was conducted over a three-day period using the computer-assisted web interviewing (CAWI) method. The sample was representative of the adult Polish population in terms of gender, age, and geographical location. Data collection occurred 14 months after the implementation of legal restrictions on ED sales to minors. Results: Among 1121 adults (54.3% female), 15.1% reported weekly ED consumption, 9.7% monthly, 13.3% less than monthly, and 62.0% never. Younger age (p < 0.05), male gender (aOR = 1.63 [1.25–2.13]; p < 0.001), and active occupational status (aOR = 1.63 [1.19–2.24]; p = 0.002) were significantly associated with ED use. Overall, 83.0% of respondents perceived EDs as harmful, and 87.2% supported the sales ban to minors, although only 45.6% considered the ban effective. Additionally, 31.8% had observed minors consuming EDs in the past 30 days. Sociodemographic characteristics were associated with risk perception and support for regulation: women (aOR = 1.50), individuals with higher education (aOR = 1.44), and those with good financial status (aOR = 2.35) were more likely to perceive EDs as harmful and endorse regulatory measures. Conclusions: Educational interventions should prioritize young adults, particularly males, who constitute the primary consumers. There is also a need to enhance enforcement mechanisms to limit minors’ access to energy drinks and curb their marketing and availability, thereby improving public health protection.

Psychotherapy is a well-established method of treating many mental disorders. It has been proven that psychotherapy leads to structural and functional changes in the brain; however, knowledge about the molecular and cellular mechanisms of these changes is limited. Neuroplasticity and one of its mediators, brain-derived neurotrophic factor (BDNF), are potential research targets in this field. To define the role of BDNF concentration in serum, or in plasma, and BDNF promoter gene methylation in saliva or leucocytes, in psychotherapy, an extensive literature search was conducted in the PubMed and Web of Science databases. The literature review was conducted based on papers published up until May 2021 that included pre and post psychotherapy measurements of either BDNF concentration levels or promoter gene methylation status. Ten studies were indicated as eligible for analysis: eight studies that investigated peripheral BDNF concentration levels, one study that investigated methylation status, and one study that included an evaluation of both subject matters. Patients underwent cognitive behavioral therapy or interpersonal psychotherapy. Patients were diagnosed with borderline personality disorder, major depressive disorder, anorexia nervosa, bulimia nervosa, or post-traumatic stress disorder. There were only three of the nine studies that showed statistically significant increases in BDNF concentration levels after psychotherapy. The two studies that involved BDNF gene methylation status showed a decrease in methylation after dialectical behavioral therapy of borderline patients.

From 1 January 2024, the sale of energy drinks (EDs) containing caffeine (CAF) and taurine (TA) was legally banned in Poland for minors (under age 18 years). EDs pose a significant public health concern, with their consumption steadily rising among young people globally. These beverages are rich in CAF, sugar, and other stimulants, making them particularly attractive to adolescents seeking energy boosts during physical or mental exertion. ED consumption patterns vary based on sociodemographic factors, with gender playing a notable role. The consumption of EDs by children and adolescents has been linked to adverse health effects and risky behaviors, potentially affecting their overall well-being. Excessive ED consumption is a widespread issue, prompting numerous countries to implement regulatory measures, such as sales restrictions for under those under age 18 years, warning labels, and mandatory disclosure of CAF content. This review examines ED consumption among people under age 18 years in Poland, focusing on the associated health and regulatory challenges of the newly introduced sales prohibition. Despite the growing popularity of EDs among young people, Poland lacks systematic studies on their consumption, particularly among children, adolescents, and young adults. Beyond legal restrictions, coordinated health policies and education about the risks of ED consumption and natural alternatives are crucial to addressing this issue. This article aims to review the background to the reasons for the ban of sale of energy drinks to young people in Poland from January 2024.

Background: Research on personality types among doctors reveals its impact on medical specialty choices, suggesting that considering personality in career planning may enhance work satisfaction and reduce burnout risks. Objective: This study, encompassing 2104 medical students, explores how personality types, traits, and gender relate to specialty preferences. Methods: Participants of this study were medical students from various universities in Poland. The study surveyed 2104 participants. Each participant completed a general questionnaire and a NERIS Type Explorer personality test, based on the Myers-Briggs Type Indicator inventory and the “Big Five” personality traits concept. The questionnaire was distributed on social media groups for medical students from all Polish universities. An exploratory statistical analysis was performed to find relationships. For each tested relationship a Fisher exact test was conducted and the significance level was P<.05. Each test resulted in a P value and odds ratio (OR) with a CI. To ensure we included undecided students and obtained meaningful data, we allowed participants to select up to three medical specialties from the 77 available in Poland at the time of the study. Results: The findings unveil significant relationships between gender, personality types, traits, and specialty preferences. Women tended to favor Neonatology (OR 9.15, 95% CI 3.02-45.46), while men leaned toward Orthopedics and traumatology of the locomotor system (OR 7.53, 95% CI 4.87-11.94). Extroverted, Intuitive, Feeling, Prospecting, and Turbulent students showed a heightened interest in Psychiatry (OR 2.23, 95% CI 1.64-3.01), whereas Introverted, Observant, Feeling, Judging, and Turbulent types favored Family Medicine (OR 2.98, 95% CI 2.08-4.24) and Pediatrics (OR 2.13, 95% CI 1.51-2.99). Conclusions: In conclusion, this research establishes a link between personality and medical specialty selection. Taking into account the significant role of personality traits, it should be considered to integrate them into the process of selecting a medical career or designing a medical curriculum. This approach may allow for the customization of programs to match students’ traits, thereby cultivating improved clinical communication skills, fostering interprofessional collaboration and ultimately enhancing treatment outcomes and professional fulfillment among physicians. The main limitation of this study is that it was conducted on medical students, who lack the full knowledge of the work as a specific specialist. A study surveying medical doctors with longer internships across different wards could be conducted to check for any variabilities. Moreover, there are other significant factors that influence one’s medical specialty choice. Certainly, this area could be further explored.