The sustainable evolution of modern nuclear science hinges on solving a central, multiscale challenge: understanding, predicting, and controlling the fundamental interactions between ionizing radiation and functional materials. Driven by the dual imperatives of decarbonized energy generation and precision healthcare, my academic and research program establishes a bridge connecting fundamental subatomic physics, high-performance computational modeling, and advanced materials engineering. Rooted in a rigorous doctoral foundation at Université Paris-Sud 11 and expanded through extensive professorial leadership at the National School of Advanced Sciences and Technologies of Borj Cédria (ENSTAB), my work deciphers how radiation fields alter matter across atomic, microscopic, and macroscopic domains. When high-energy particles traverse condensed matter, they trigger intricate chains of energy deposition, atomic displacements, electronic excitations, and nuclear transmutations. In conventional frameworks, these phenomena are frequently treated in isolation—approached either as materials degradation challenges in reactor vessels or as localized dose-deposition calculations in medical physics. My laboratory unifies these perspectives under a coherent predictive paradigm.