Cecilia Roque

Dr. Cecilia Roque

Biomolecular Engineering Lab, Universidade Nova de Lisboa, Portugal
orcid

Research Focus & Metrics

Academic Career Length

23Years (2004-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2011 in Biotechnology Advances
Verified
Journal Article
Closed access
ADA.M.G.C. Dias
A.M.G.C. Dias
AHA. Hussain
A. Hussain
AMA.S. Marcos
A.S. Marcos
CRCecilia Roque
Cecilia Roque

4 June 2004 in Biotechnology Progress
Verified
Journal Article
Closed access
PDF file
CRCecilia Roque
Cecilia Roque
CLC.R. Lowe
C.R. Lowe
MTM. Ângela Taipa
M. Ângela Taipa
Antibodies and antibody derivatives constitute 20 % of biopharmaceutical products currently in development, and despite early failures of murine products, chimeric and humanized monoclonal antibodies...

1 August 2007 in Journal of Chromatography A
Verified
Journal Article
Closed access
CRCecilia Roque
Cecilia Roque
CSCláudia S.O. Silva
Cláudia S.O. Silva
MTM. Ângela Taipa
M. Ângela Taipa

1 December 2013 in Biotechnology Advances
Verified
Journal Article
Closed access
LBL. Borlido
L. Borlido
AAAna Azevedo
Ana Azevedo
CRCecilia Roque
Cecilia Roque
MAM.R. Aires-Barros
M.R. Aires-Barros

19 July 2018 in Biotechnology Journal
Verified
Journal Article
Open access
PDF file
GMGaetano Maugeri
Gaetano Maugeri
ILIana Lychko
Iana Lychko
RSRita G. Sobral
Rita G. Sobral
CRCecilia Roque
Cecilia Roque
Antimicrobial resistance is one of the most worrying threats to humankind with extremely high healthcare costs associated. The current technologies used in clinical microbiology to identify the bacterial agent and profile antimicrobial susceptibility are time‐consuming and frequently expensive. As a result, physicians prescribe empirical antimicrobial therapies. This scenario is often the cause of therapeutic failures, causing higher mortality rates and healthcare costs, as well as the emergence and spread of antibiotic resistant bacteria. As such, new technologies for rapid identification of the pathogen and antimicrobial susceptibility testing are needed. This review summarizes the current technologies, and the promising emerging and future alternatives for the identification and profiling of antimicrobial resistance bacterial agents, which are expected to revolutionize the field of clinical diagnostics.

1 December 2018 in Trends in Biotechnology
Verified
Journal Article
Open access
ABArménio J.M. Barbosa
Arménio J.M. Barbosa
AOAna Rita Oliveira
Ana Rita Oliveira
CRCecilia Roque
Cecilia Roque
Animals' olfactory systems rely on proteins, olfactory receptors (ORs) and odorant-binding proteins (OBPs), as their native sensing units to detect odours. Recent advances demonstrate that these proteins can also be employed as molecular recognition units in gas-phase biosensors. In addition, the interactions between odorant molecules and ORs or OBPs are a source of inspiration for designing peptides with tunable odorant selectivity. We review recent progress in gas biosensors employing biological units (ORs, OBPs, and peptides) in light of future developments in artificial olfaction, emphasizing examples where biological components have been employed to detect gas-phase analytes.