Because of the promising results obtained by machine learning (ML) approaches in several fields, every day is more common, the utilization of ML to solve problems in bioinformatics. In genomics, a current issue is to detect and classify transposable elements (TEs) because of the tedious tasks involved in bioinformatics methods. Thus, ML was recently evaluated for TE datasets, demonstrating better results than bioinformatics applications. A crucial step for ML approaches is the selection of metrics that measure the realistic performance of algorithms. Each metric has specific characteristics and measures properties that may be different from the predicted results. Although the most commonly used way to compare measures is by using empirical analysis, a non-result-based methodology has been proposed, called measure invariance properties. These properties are calculated on the basis of whether a given measure changes its value under certain modifications in the confusion matrix, giving comparative parameters independent of the datasets. Measure invariance properties make metrics more or less informative, particularly on unbalanced, monomodal, or multimodal negative class datasets and for real or simulated datasets. Although several studies applied ML to detect and classify TEs, there are no works evaluating performance metrics in TE tasks. Here, we analyzed 26 different metrics utilized in binary, multiclass, and hierarchical classifications, through bibliographic sources, and their invariance properties. Then, we corroborated our findings utilizing freely available TE datasets and commonly used ML algorithms. Based on our analysis, the most suitable metrics for TE tasks must be stable, even using highly unbalanced datasets, multimodal negative class, and training datasets with errors or outliers. Based on these parameters, we conclude that the F1-score and the area under the precision-recall curve are the most informative metrics since they are calculated based on other metrics, providing insight into the development of an ML application.

In this paper we present an agent-based application of a wireless tourist guide that combines the Beliefs-Desires-Intentions approach with learning capabilities of Case Base Reasoning techniques. This application shows how to develop adaptive agents with a goal driven design and a decision process built on a CBR architecture. The resulting agent architecture has been validated by real users who have used the tourist guide application, on a mobile device, and can be generalized for the development of other personalized services.

Convolutional Neural Networks (CNNs) have proven effective in automated plant disease diagnosis, significantly contributing to crop health monitoring. However, their limited interpretability hinders practical deployment in real-world agricultural settings. To address this, we explore advanced CNN architectures, namely ResNet-50 and EfficientNet, augmented with attention mechanisms. These models enhance accuracy by optimizing depth, width, and resolution, while attention layers improve transparency by focusing on disease-relevant regions. Experiments using the PlantVillage dataset show that basic CNNs achieve 46.69% accuracy, while ResNet-50 and EfficientNet attain 63.79% and 98.27%, respectively. On a 39-class extended dataset, our proposed EfficientNet-B0 with attention (EfficientNetB0-Attn), integrating an attention module at layer 262, achieves 99.39% accuracy. This approach significantly enhances interpretability without compromising performance. The attention module generates weights via backpropagation, allowing the model to emphasize disease-relevant image regions, thereby enhancing both accuracy and interpretability.

COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has a case-fatality rate of 2–3%, with higher rates among elderly patients and patients with comorbidities. Radiologically, COVID-19 is characterised by multifocal ground-glass opacities, even for patients with mild disease. Clinically, patients with COVID-19 present respiratory symptoms, which are very similar to other respiratory virus infections. Our knowledge regarding the SARS-CoV-2 virus is still very limited. These facts make it vitally important to establish mechanisms that allow to model and predict the evolution of the virus and to analyze the spread of cases under different circumstances. The objective of this article is to present a model developed for the evolution of COVID in the city of Manizales, capital of the Department of Caldas, Colombia, focusing on the methodology used to allow its application to other cases, as well as on the monitoring tools developed for this purpose. This methodology is based on a hybrid model which combines the population dynamics of the SIR model of differential equations with extrapolations based on recurrent neural networks. This combination provides self-explanatory results in terms of a coefficient that fluctuates with the restraint measures, which may be further refined by expert rules that capture the expected changes in such measures.