Mr. Isao Yokota is a full-time Associate Professor of Biostatistics at Hokkaido University Faculty of Medicine, Hokkaido, JAPAN. with about 10 years of academic experience. He designs and conducts epidemiologic study, and clinical trials and has authored over 120 peer -reviewed articles. He has been a councilor in the biometrics Society of Japan and a biostatistical committee member in Japan Children Cancer Group since 2015. His current interests are prediction models for survival outcome and clinical trial design in a small sample size.