Os recursos naturais provindos das palmeiras Euterpe oleracea, Astrocaryum aculeatum, Mauritia flexuosa, Bactris gasipaes, Oenocarpus bacaba e Attalea maripa potencialmente favorecem o aproveitamento da biodiversidade e são economicamente viáveis ao mercado nacional, em virtude do aproveitamento integral de seus produtos e subprodutos. O objetivo desta pesquisa foi realizar uma prospecção baseada na busca de patentes e produção científica de modo a identificar as potencialidades para a bioeconomia das palmeiras nativas da região amazônica brasileira. Para isso, foi realizado uma pesquisa documental exploratória de abordagem quantitativa, analisando os documentos de patentes depositados aos bancos de dados do Instituto Nacional de Propriedade Industrial do Brasil, Banco de Patentes Latino-americanas, United States Patent and Trademark Office, European Patent Office e World Intellectual Property Organization. Para a prospecção científica, foram utilizados artigos publicados nas plataformas de pesquisas da Elsevier, as quais incluíram Scopus e Science Direct, como também as bases de dados da Springer Link, SciELO e o Periódico da Capes. Os resultados da prospecção foram compilados em redes de dados e gráficos. Do ponto de vista científico, as espécies Euterpe oleracea e Mauritia flexuosa se destacam por serem fonte de recursos biológicos com potencial bioeconômico, e apresentam um extenso número de publicações, no que se refere as atividades químicas dos frutos. O United States Patent and Trademark Office apresenta o maior número de depósitos de patentes para a espécie Euterpe oleracea. Nesta constata-se que o Brasil lidera como principal país depositante, devido à alta riqueza dessas espécies. Dentre os depósitos de patentes pesquisados, foram classificados principalmente pelo código A61K, o qual é relacionado à obtenção de comprimidos contendo extrato etanólico (padronizado) dos frutos de Euterpe oleracea e sua aplicação como antioxidante. Diante da presente análise, este estudo possibilitou apresentar uma visão geral das potencialidades tecnológicas e científicas das espécies de palmeiras. O estudo revela de forma significativa o potencial das palmeiras para atender as necessidades humanas na área de alimentação e saúde, e estas podem ser exploradas de uma forma ainda mais significativa pela indústria, com perspectiva para geração de novas tecnologias.

Fibrinolytic enzymes are proteases that are capable of degrading the fibrin mesh present in blood clots and can be obtained through fungal extracts. Thus, the objective of this paper was to seek out and compare all the information regarding the production and biochemical characterization of fibrinolytic enzymes of mushroom species published in papers in the last ten years. The research was carried out in eight national and international electronic databases using the terms: “fungal enzymes”, “fibrinolytic Proteases”, “thrombosis” and “mushrooms”. The results obtained were analyzed according to each step. In the first stage, the titles and abstracts of all papers were analyzed independently; in the second stage, all papers were read and those that did not meet the inclusion criteria were excluded. Then, the remaining papers were reviewed and the data were tabulated and compared. As a result, it was found that enzymes with fibrinolytic action were obtained from eight species of mushrooms in the period of this research: P. sajor-cashew, P. ferulae, P. ostreatus, L. shimeji, A. polytricha, H. erinaceum, C. comatus and C. militaris. The enzymes were identified as protease SPPs, metalloproteases, serine proteases and serine metalloproteases. The methods used to evaluate fibrinolytic activity were the fibrin plate method and/or the formation of artificial thrombus through thrombin and fibrinogen. The molecular mass of these enzymes ranged from ~18 to 66 kDa and, for the biochemical characterization of the extracts, the pH ranged from 4.0 to 9.5 and the optimum temperature from 25 to 70 ºC. Via the review, it was observed that few articles were published on the subject in question, which made it necessary to carry out more studies to discover the biotechnological properties of mushrooms and define their applications in the most diverse sectors of industries, not only in commercial species of mushrooms, but also in native species.

To investigate the biocatalytic potential of Amazonian actinomycetes for monoterpenes biotransformation. To carry out the present study, eleven actinomycetes of the genus Streptomyces isolated from inga-cipó (Inga edulis Mart.) rhizospheres were tested for their ability to bioconvert the substrates R-(+)-limonene, S-(-)-limonene, 1S-(-)-α-pinene, and (-)-β-pinene as sole carbon and energy source. According to gas chromatography-mass spectrometry analysis, three strains, LabMicra B270, LaBMicrA B310, and LaBMicrA B314, were able to biotransform 1S-(-)-α-pinene after 96 h of growth. However, Streptomyces LaBMicrA B270 was the most promising since it converted after only 72 h all the 1S-(-)-α-pinene mainly into cis-verbenol (74.9±1.24%) and verbenone (18.2±1.20%), compounds that have important biological activities and great industrial interest as additives in foods and cosmetics. These findings can stimulate the development of natural aromas using naturally abundant monoterpenes, ratify the potential of microorganisms from almost unexplored niches such as the Amazonian rhizosphere, and reinforce the importance of preserving those niches.

The number of aroma compounds obtained by biotechnological process has increased tremendously in recent years and, as a result, are now being extensively employed in order to make products more attractive for consumers. In the present review, we inten to assess the wide range of reactions are catalyzed by fungal strains in regards to biotransformation of limonene and pinene for the aroma compounds production, their production rates/maximum concentrations and their biological potential. We comprehensively summarized in this review available data (2000–2021) regarding fungal biotransformation of limonene and pinene as biotechnological processes. Over the past years, has been paid to the biotransformation processes due to mild and environmentally friendly conditions applied. This review has shown that reports on the application of the fungi as a promising source of biocatalysts, mainly for stereoselective reactions such as hydroxylation and epoxidation. Studies have demonstrated the existence of promising monoterpenes used as substrates, which could be important from an industrial standpoint since this increases their importance as starting materials for obtaining aromatic molecules new. Moreover, biological (e.g.,antioxidant, anticancer) activities attributed to some monoterpene biotransformation products are increasingly being reported, indicating that their applications may transcend food, cosmetic and pharmaceutical industry.