Nick Preston

Dr. Nick Preston


Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2022 in Journal of Medical Virology
Verified
Journal Article
Open access
MSManoj Sivan
Manoj Sivan
NPNick Preston
Nick Preston
APAmy Parkin
Amy Parkin
SMSophie Makower
Sophie Makower
JGJeremy Gee
Jeremy Gee
MHMike Horton
Mike Horton
Background: The C19‐YRS is the literature's first condition‐specific, validated scale for patient assessment and monitoring in Post‐COVID‐19 syndrome (PCS). The 22‐item scale's subscales (scores) are symptom severity (0–100), functional disability (0–50), additional symptoms (0–60), and overall health (0–10).Objectives: This study aimed to test the scale's psychometric properties using Rasch analysis and modify the scale based on analysis findings, emerging information on essential PCS symptoms, and feedback from a working group of patients and professionals.Methods: Data from 370 PCS patients were assessed using a Rasch Measurement Theory framework to test model fit, local dependency, response category functioning, differential item functioning, targeting, reliability, and unidimensionality. The working group undertook iterative changes to the scale based on the psychometric results and including essential symptoms.Results: Symptom severity and functional disability subscales showed good targeting and reliability. Post hoc rescoring suggested that a 4‐point response category structure would be more appropriate than an 11‐point response for both subscales. Symptoms with binary responses were placed in the other symptoms subscale. The overall health single‐item subscale remained unchanged.Conclusion: A 17‐item C19‐YRSm was developed with subscales (scores): symptom severity (0–30), functional disability (0–15), other symptoms (0–25), and overall health (0–10).

1 August 2016 in Clinical Rehabilitation
Verified
Journal Article
Open access
NPNick Preston
Nick Preston
SMSara Magallón
Sara Magallón
LHLiam Jb Hill
Liam Jb Hill
EAElizabeth Andrews
Elizabeth Andrews
SASara M Ahern
Sara M Ahern
MMMark Mon-Williams
Mark Mon-Williams
Objective: To identify effective motor training interventions for children with developmental coordination disorder from research graded as high quality (using objective criteria) for the purpose of informing evidence-based clinical practice. Data sources: We followed the guidance for conducting systematic reviews issued by the Centre for Reviews and Dissemination. Six OvidSP electronic databases (AMED, All EBM reviews (including Cochrane), Embase, Ovid MEDLINE, PsychARTICLES Full Text, PsycINFO) were searched systematically. We aimed to retain only randomized control trials and systematic reviews of randomized control trials, defined as the highest level of evidence by the Oxford Centre for Evidence-Based Medicine. We searched reference lists of retained articles to identify further appropriate articles. Review methods: Two reviewers critically appraised and categorized articles by effect size (including confidence intervals), inclusion of power calculations and quality using the Physiotherapy Evidence Database (PEDro) scale. Only studies scoring seven or more on the PEDro scale (classed by the PEDro as high reliability) were retained. Results: No systematic reviews met our criteria for inclusion from 846 articles yielded by the systematic search. Nine randomized control trials investigating 15 interventions to improve motor skills met our inclusion criteria for ‘high quality’. Nevertheless, not all included studies were adequately powered for determining an effect. Conclusion: Large effect sizes associated with 95 % confidence intervals suggest that ‘Neuromotor Task Training’, ‘Task-oriented Motor Training’ and ‘Motor Imagery + Task Practice Training’ are the most effective reported interventions for improving motor skills in children with developmental coordination disorder.

16 May 2022 in BMJ Open
Verified
Journal Article
Open access
PDF file
MSManoj Sivan
Manoj Sivan
TGTrisha Greenhalgh
Trisha Greenhalgh
JDJulie Lorraine Darbyshire
Julie Lorraine Darbyshire
GMGhazala Mir
Ghazala Mir
DODaryl O'Connor
Daryl O'Connor
BDBrendan Delaney
Brendan Delaney
Introduction Long COVID, a new condition whose origins and natural history are not yet fully established, currently affects 1.5 million people in the UK. Most do not have access to specialist long COVID services. We seek to optimise long COVID care both within and outside specialist clinics, including improving access, reducing inequalities, helping self-management and providing guidance and decision support for primary care. We aim to establish a ‘gold standard’ of care by systematically analysing current practices, iteratively improving pathways and systems of care. Methods and analysis This mixed-methods, multisite study is informed by the principles of applied health services research, quality improvement, co-design, outcome measurement and learning health systems. It was developed in close partnership with patients (whose stated priorities are prompt clinical assessment; evidence-based advice and treatment and help with returning to work and other roles) and with front-line clinicians. Workstreams and tasks to optimise assessment, treatment and monitoring are based in three contrasting settings: workstream 1 (qualitative research, up to 100 participants), specialist management in 10 long COVID clinics across the UK, via a quality improvement collaborative, experience-based co-design and targeted efforts to reduce inequalities of access, return to work and peer support; workstream 2 (quantitative research, up to 5000 participants), patient self-management at home, technology-supported monitoring and validation of condition-specific outcome measures and workstream 3 (quantitative research, up to 5000 participants), generalist management in primary care, harnessing electronic record data to study population phenotypes and develop evidence-based decision support, referral pathways and analysis of costs. Study governance includes an active patient advisory group. Ethics and dissemination LOng COvid Multidisciplinary consortium Optimising Treatments and servIces acrOss the NHS study is sponsored by the University of Leeds and approved by Yorkshire & The Humber—Bradford Leeds Research Ethics Committee (ref: 21/YH/0276). Participants will provide informed consent. Dissemination plans include academic and lay publications, and partnerships with national and regional policymakers. Trial registration number NCT05057260, ISRCTN15022307.

11 May 2021 in Measurement in Physical Education and Exercise Science
Verified
Journal Article
Open access
LELucy Eddy
Lucy Eddy
LHLiam J.B. Hill
Liam J.B. Hill
MMMark Mon-Williams
Mark Mon-Williams
NPNick Preston
Nick Preston
ADAndrew Daly-Smith
Andrew Daly-Smith
DBDaniel Bingham
Daniel Bingham
Evidence suggests that children struggle to acquire age-appropriate fundamental movement skills (FMS), despite their importance for facilitating physical activity. This has led to calls for routine school-based screening of children’s FMS. However, there is limited research exploring schools’ capacity to conduct such assessments. This study investigated what factors might affect the adoption and implementation of FMS assessments in primary schools. School staff (n = 853) completed an online questionnaire developed using the Capability, Opportunity, Motivation and Behavior (COM-B) model. A majority reported that knowledge of pupils’ FMS ability would be beneficial (65.3%), and 71.8% would assess FMS if support was provided. Barriers included: Capability – few possessed knowledge of FMS (15%); Opportunity – teachers reported 30–60 minutes as acceptable for assessing a class, a substantially shorter period than current assessments require; Motivation – 57.2% stated FMS assessments would increase workload stress. Solutions to these issues are discussed using the COM-B theoretical framework.

1 March 2011 in Journal of Rehabilitation Medicine
Verified
Journal Article
Open access
BBB Bhakta
B Bhakta
Andrew Patrick Hayes WeightmanAndrew Patrick Hayes Weightman
Andrew Patrick Hayes Weightman
NPNick Preston
Nick Preston
MLM Levesley
M Levesley
RHR Holt
R Holt
ACAj Cozens
Aj Cozens
Objective: We developed a home-based rehabilitation exercise system incorporating a powered joystick...

19 July 2021 in Topics in Stroke Rehabilitation
Verified
Journal Article
Open access
LLLutong Li
Lutong Li
QFQiang Fu
Qiang Fu
STSarah F. Tyson
Sarah F. Tyson
NPNick Preston
Nick Preston
Andrew Patrick Hayes WeightmanAndrew Patrick Hayes Weightman
Andrew Patrick Hayes Weightman
Home-based robotic therapy is a trend of post-stroke upper limb rehabilitation. Although home-based upper limb rehabilitation robots have been developed over several decades, no design specificatio...