Professor Gorrell trained at Australian National University, University of Melbourne and Johns Hopkins University. His training encompassed parasitology, virology, immunity, serology, cell biology and protein biochemistry. His research experience includes disease pathogenesis, particularly liver fibrosis, cancer and fatty liver, small RNA viruses, protein structure, proteases, mouse models of liver disease, transcriptomics and proteomics. He is expert in the DPP4 enzyme family including FAP-alpha, DPP8 and DPP9. He has authored over 160 publications attracting H index 50, i10 index 113 and over 8,100 citations. Mark has supervised more than 19 PhD and M Phil students and 23 honours students.