Right ventricular (RV) function is one of the critical factors affecting the prognosis of fetuses with hypoplastic left heart syndrome (HLHS). Our study objectives included assessment of cardiac function and comprehensive measurement of cardiac microstructure. We retrospectively studied 42 fetuses diagnosed as HLHS by echocardiography. Myocardial deformation of the right ventricular wall was calculated automatically in offline software. Postmortem cardiac imaging for three control fetal hearts and four HLHS specimens was performed by a 9.4T DTI scanner. Myocardial deformation parameters of the RV (including strain, strain rate, and velocity) were significantly lower in HLHS fetuses (all p < 0.01). FA values increased (0.18 ± 0.01 vs. 0.21 ± 0.02; p < 0.01) in HLHS fetuses, but MD reduced (1.3 ± 0.15 vs. 0.88 ± 0.13; p < 0.001). The HLHS fetuses’ RV lateral base wall (−7.31 ± 51.91 vs. −6.85 ± 31.34; p = 0.25), middle wall (1.71 ± 50.92 vs. −9.38 ± 28.18; p < 0.001), and apical wall (−6.19 ± 46.61 vs. −11.16 ± 29.86, p < 0.001) had HA gradient ascent but HA gradient descent in the anteroseptal wall (p < 0.001) and inferoseptal wall (p < 0.001). RV basal lateral wall HA degrees were correlated with RVGLS (R² = 0.97, p = 0.02). MD values were positively correlated with RVGLS (R² = 0.93, p = 0.04). Our study found morphological and functional changes of the RV in HLHS fetuses, and cardiac function was related to the orientation patterns of myocardial fibers. It may provide insight into understanding the underlying mechanisms of impaired RV performance in HLHS.

This study addresses the challenges associated with single-system long-baseline real-time kinematic (RTK) navigation, including limited positioning accuracy, inconsistent signal reception, and significant residual atmospheric errors following double-difference corrections. This study explores the effectiveness of long-baseline RTK navigation using an integrated system of the BeiDou Navigation Satellite System (BDS), Global Positioning System (GPS), and Galileo Satellite Navigation System (Galileo). A long-baseline RTK approach that incorporates Kalman filtering and partial ambiguity resolution is applied. Initially, error models are used to correct ionospheric and tropospheric delays. The zenith tropospheric and inclined ionospheric delays and additional atmospheric error components are then regarded as unknown parameters. These parameters are estimated together with the position and ambiguity parameters via Kalman filtering. A two-step method based on a success rate threshold is employed to resolve partial ambiguity. Data from five long-baseline IGS monitoring stations and real-time measurements from a ship were employed for the dual-frequency RTK positioning experiments. The findings indicate that integrating additional GNSSs beyond the BDS considerably enhances both the navigation precision and the rate of ambiguity resolution. At the IGS stations, the integration of the BDS, GPS, and Galileo achieved navigation precisions of 2.0 cm in the North, 5.1 cm in the East, and 5.3 cm in the Up direction while maintaining a fixed resolution exceeding 94.34%. With a fixed resolution of Up to 99.93%, the integration of BDS and GPS provides horizontal and vertical precision within centimeters in maritime contexts. Therefore, the proposed approach achieves precise positioning capabilities for the rover while significantly increasing the rate of successful ambiguity resolution in long-range scenarios, thereby enhancing its practical use and exhibiting substantial application potential.

The third generation of the Beidou navigation satellite system (BDS-3) broadcasts navigation signals of five frequencies. Focusing on the deep integration of five-frequency signals, we applied the joint BDS-3 five-frequency undifferenced and uncombined precise point positioning (UC-PPP) to analyze the receiver inter-frequency biases (IFB). Firstly, 12 Multi-GNSS Experiment tracking (MGEX) stations are selected to investigate the time-varying characteristics of receiver IFB and, according to random characteristics, three random modeling schemes are proposed. Secondly, the effects of three stochastic modeling methods on zenith tropospheric delay, ionospheric delay, floating ambiguity, and quality control are analyzed. Finally, the effects of three IFB stochastic modeling methods on positioning performance are evaluated. The results showed that the amplitude in the IFB for B2b is 5.139 m, B2a is 1.964 m, and B1C is 0.950 m by measuring one week’s observation data. The IFB stochastic modeling method based on random walks can shorten the PPP convergence time by 4~12%, diminish the false alarm of quality control, and improve the positioning accuracy. The random walk model is recommended to simulate the variation of IFB, which can not only overcome the disadvantage of the time constant model being unable to accurately describe the time-varying characteristics of the IFB, but also avoid reducing the strength of the kinematic PPP positioning model due to the large process noise of the white noise model.

Ocean tidal variation is a key parameter for ensuring coastal safety, monitoring marine climate, and maintaining elevation datum. Recently, the ground-based global navigation satellite system reflectometry (GNSS-R) technique has been applied for regional tidal measurements, which is somewhat restricted in terms of temporal and spatial resolutions. A convenient method to improve temporal resolution of measurements is to combine multi-GNSS observations. This paper proposes a new sea-surface altimetry method using the posterior errors (PE) of dual-frequency carrier-phase signals derived from the ionosphere-free Precise Point Positioning (IF-PPP). Considering that the number of initial retrievals is obviously unsuitable for minute-level tidal measurements, both the time sliding window based on the Lomb–Scargle periodogram and a weighted cubic spline smoothing function are significant processing steps for estimating the reflector heights between the sea surface and antenna center. Measurements from two coastal GNSS stations with different tidal amplitudes are used to test the proposed method and compare it with the tide gauge and the signal-to-noise ratio (SNR) methods, respectively. The experimental results show that the multi-GNSS PE combination method can be used to estimate a minute-level sea level time series, and its root-mean-squared errors (RMSE) are about 12.5 cm. In terms of correlation, for all results, the corresponding coefficients exceed 0.97. Moreover, this combined PE method demonstrates a significant advantage in increasing temporal resolution, which is beneficial for application on high-frequency sea-level monitoring.