To describe the current scientific knowledge on the effects of physical exercise on the growth of children and adolescents since intrauterine life. A search was carried out in the Medline, Embase, Scielo, and Cochrane databases of studies published from 1990 to 2018. The authors included studies with different designs: clinical trials, cohort, cross-sectional and review studies. Studies that addressed the subject of physical exercise or physical activity, and weight-height growth or bone or muscle tissue growth were identified. These studies were analyzed, classified, and presented by age group: fetuses, preterm newborns, preschoolers, schoolchildren, and adolescents. It was observed that almost all studies indicated the safety of physical exercises, of mild to moderate intensity, for pregnant women, as well as children and adolescents, including both aerobic and anaerobic exercises. The retrieve studies did not demonstrate that the practice of physical exercises or certain sports, especially basketball and floor gymnastics, influenced the linear growth of children or adolescents. Some studies showed an increase in bone and muscle tissue growth in child and adolescent athletes. Despite the small number of studies with adequate methodology, especially randomized clinical trials, evidence appears to indicate that physical exercise is safe for both the pregnant woman and the child, from fetal life to adolescence. Physical exercise does not appear to impair the child's linear growth and contributes to the ideal shaping of bone and muscle tissues, ensuring possible beneficial effects throughout life.

Objective To describe the neurodevelopment of children with congenital Zika syndrome during the second year of life. Design Case series study. Setting Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Pernambuco, Brazil. Participants 24 children with congenital Zika syndrome born with microcephaly during the Zika outbreak in Brazil in 2015 and followed up at the IMIP during their second year of life. Main outcome measure Denver Developmental Screening Test II, head circumference and clinical neurological examination. Results All children presented neurodevelopmental delay: for an average chronological age of 19.9 months, language was equivalent to that of age 2.1 months, gross motor 2.7 months, fine motor/adaptive 3.1 months and personal/social 3.4 months. Head circumference remained below the third percentile for age and gender, and growth rate up to the second year of life was 10.3 cm (expected growth 13 cm). Muscle tone was increased in 23 (95.5%) of 24 children, musculotendinous reflexes were increased in the whole sample and clonus was present in 18 (77.3%) of 24 children. All children except one had epilepsy. Conclusion Children born with microcephaly associated with congenital Zika virus have a significant neurodevelopmental delay.

To verify the association between early-life nutrition and chronic adult diseases. Medline, Embase, Cochrane Database, and Lilacs. The Developmental Origins of Health and Disease (DOHaD) hypothesis postulates that a mismatch between early-life circumstances and later-life situations may have an impact on chronic diseases. In this review, the authors emphasize the research supporting the impact of early nutrition on the origins of adult height, obesity and metabolic syndrome, type 2 diabetes mellitus, cardiovascular diseases, and reproductive outcomes. Even though this is a new topic and there are still many research questions to be answered, there is strong evidence that both deficiency and excess nutrition in early life can cause epigenetic changes that have effects that last a lifetime and contribute to the development of chronic diseases. Public health efforts to protect adults from getting chronic diseases should focus on nutrition in the first 1000 days of life, from conception to the end of the second year of life.

Postpartum depression (PPD) is a serious public health issue. Kangaroo mother care (KMC) is widely considered to be the most feasible, readily available and preferred intervention for decreasing neonatal morbidity and mortality in developing countries. We conducted a prospective study to assess the effect of KMC on PPD. The study population included 177 low-income mothers with their preterm infants. We used the validated Portuguese version of the Postpartum Depression Screening Scale for the assessment of maternal depression. The mothers were evaluated twice, at Neonatal Intensive Care Unit admission and at KMC discharge. We found 66 mothers (37.3%) with depression and it decreased to 30 (16.9%) after KMC intervention; p < 0.0001. None developed PPD during the Kangaroo stay. We concluded that KMC may lessen maternal depression. Further studies, may be required to clarify these preliminary findings.

To report the echocardiographic evaluation of 103 infants with presumed congenital Zika syndrome. An observational retrospective study was performed at Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil. 103 infants with presumed congenital Zika syndrome. All infants had microcephaly and head computed tomography findings compatible with congenital Zika syndrome. Zika IgM antibody was detected in cerebrospinal fluid samples of 23 infants. In 80 infants, the test was not performed because it was not available at that time. All infants had negative serology for HIV, syphilis, rubella, cytomegalovirus and toxoplasmosis. A complete transthoracic two-dimensional, M-mode, continuous wave and pulsed wave Doppler and color Doppler echocardiographic (PHILIPS HD11XE or HD15) examination was performed on all infants. 14/103 (13.5%) echocardiograms were compatible with congenital heart disease: 5 with an ostium secundum atrial septal defect, 8 had a hemodynamically insignificant small apical muscular ventricular septal defect and one infant with dyspnea had a large membranous ventricular septal defect. The echocardiograms considered normal included 45 infants with a persistent foramen ovale and 16 with a minimum patent ductus arteriosus. Preliminarily this study suggests that congenital Zika syndrome may be associated with an increase prevalence of congenital heart disease. However the types of defects noted were septal defects, a proportion of which would not be hemodynamically significant.

FUNDAMENTOS E OBJETIVOS: A prática de exercício físico, além de combater o sedentarismo, contribui de maneira significativa para a manutenção da aptidão física do idoso. O objetivo do estudo foi verificar o efeito da prática de hidroginástica sobre a aptidão física do idoso associada à saúde. METODOLOGIA: Foi realizado um ensaio controlado em 74 mulheres idosas, sem atividade física regular. Um grupo de 37 mulheres recebeu duas aulas semanais de hidroginástica durante três meses e outras 37 mulheres serviram como controle. A aptidão física foi avaliada através da bateria de testes de Rikli e Jones (1999), com avaliações de força e resistência de membros inferiores (levantar e sentar na cadeira), força e resistência de membros superiores (flexão do antebraço), flexão de membros inferiores (sentado, alcançar os membros inferiores com as mãos), mobilidade física - velocidade, agilidade e equilíbrio (levanta, caminha 2,44m e volta a sentar), flexibilidade dos membros superiores (alcançar atrás das costas com as mãos) e resistência aeróbica (andar seis minutos). A bateria de testes foi aplicada antes do início das aulas e no fim do programa após três meses. Os grupos foram semelhantes em relação a idade, IMC, renda familiar e anos de escolaridade. RESULTADOS: Ao longo dos três meses, foram acompanhadas 30 mulheres em cada grupo; perda amostral de 18,9%. Observou-se no grupo da hidroginástica um melhor desempenho em todos os pós-testes, quando comparados com os resultados do próprio grupo no pré-teste e com o controle no pós-teste (p < 0,05). CONCLUSÃO: Concluiu-se que a prática de hidroginástica para mulheres idosas sem exercícios físicos regulares contribuiu para a melhoria da aptidão física relacionada à saúde.