Context: Considering the effectiveness and safety concerns of synthetic intracanal medicaments (ICM), alternative usage of herbal ingredients in the root canal treatment may prove to be beneficial. Hence, the naturally available potent proteolytic, anti-inflammatory, and antimicrobial pineapple extract Bromelain as an ICMs needs to be studied. Aim: The aim of this study is to evaluate and compare the antimicrobial efficacy of calcium hydroxide (CaOH) and triple antibiotic paste (TAP) with Bromelain against Enterococcus faecalis bacteria using the turbidity method. Materials and Methods: Forty-four freshly extracted single-rooted teeth were collected and 6 mm sections were prepared. These samples were infected with E. faecalis bacteria (ATCC 29212), randomly divided into four groups. Negative control, CaOH paste, TAP, and Bromelain paste. After the removal of medicament, the optical density (OD) of the dentinal shavings was measured using a spectrophotometer. Statistical Analysis: The Chi-square and Kruskal − Wallis ANOVA test were used. The confidence interval was set to 95% at 5% significance level. Results: TAP showed less OD than CaOH₂ paste which is statistically significant. (P = 0.0022). The OD reading of Bromelain paste was less than CaOH₂ with P = 0.007. The OD of Bromelain and TAP were statistically insignificant (P = 0.095), indicating their comparable antibacterial efficacy. Conclusions: The antimicrobial efficiency of Bromelain was found to be more effective than Ca (OH) ₂ paste and comparable to TAP against E. faecalis.

Pulpitis is a special disease of dental pulp. It causes localized inflammation, due to various inflammatory mediators such as cytokines and chemokines. These inflammatory mediators are responsible for various reparative and resorptive processes in the dental pulp. The balance between these processes ultimately determines the viability of the tooth. Due to the important properties of various inflammatory markers, the correlation of cytokinin gene expression in various stages of inflammation becomes necessary to focus on. Several studies in the past have focused on the importance of such correlation to help in diagnostic applications. The nature of these inflammatory mediators can help us in diagnostic evaluation. Several attempts have been made to focus on these associations so that it can assist in making clinical decisions effectively. The data available are vast but are the most neglected topic. This review article briefly outlines and summarizes the importance of various inflammatory mediators such as cytokinin and chemokines in various pathways of pulpal and periapical inflammation in explanatory and diagrammatic forms. Knowledge gained about pulpal inflammatory response may aid in understanding the molecular level of inflammatory pulpal and periapical diseases, which shall modify our future diagnostic modalities. Several medicaments are used in the treatment of minimal to advanced dental caries which leads to periapical infections. Thorough understanding of these medicaments can resolve secondary infection and can improve the prognosis of the treated tooth.

The primary goal of this study was to assess the prevalence of oral involvement and, secondarily, the likely variables in patients with confirmed COVID-19 accompanied by mucormycosis infection. The study design was a cross-sectional descriptive sort that was performed at a tertiary centre. The non-probability convenience sampling approach was used to determine the sample size. Between May 2021 and July 2021, all patients who presented to our tertiary care centre with suspected mucormycosis were considered for the investigation. The research only included individuals with proven mucormycosis after COVID-19. The features of the patients, the frequency of intraoral signs/symptoms, and the possible variables were all noted. Of the 333 COVID-19-infected patients, 47 (14%) were diagnosed with confirmed mucormycosis. The mean (SD) age of the patients was 59.7 (11.9) years. Of the 47 patients with confirmed mucormycosis, 34% showed sudden tooth mobility, 34% expressed toothache, 8.5% reported palatal eschar, 34% presented with jaw pain, 8.5% had tongue discoloration, and 17% had temporomandibular pain. About 53% of the patients were known cases of type 2 diabetes mellitus, 89% of patients had a history of hospitalization due to COVID-19 infection, 89.3% underwent oxygen support therapy, and 89.3% were administered intravenous steroids during hospitalization due to COVID-19 infection. About 14% of the suspected cases attending the mucormycosis out-patient department (OPD) had been confirmed with definite mucormycosis. Oral involvement was seen in 45% of cases of CAM (COVID-associated mucormycosis). The most frequent oral symptoms presented in CAM were sudden tooth mobility and toothache. Diabetes and steroids were the likely contributing factors associated with CAM.

Osseointegration is essential for the long-term success of dental implants. However, achieving consistent and rapid integration remains challenging. Growth factors like PDGF, BMPs, TGF-β, IGF, VEGF, PRP and PRF have shown potential to enhance bone healing and implant stability. These agents promote osteoblast activity, angiogenesis and matrix formation, accelerating peri-implant bone regeneration. Delivery methods such as platelet concentrates, surface coatings and biomaterial integration have demonstrated promising outcomes. Therefore, it is of interest to review summarizing the biological rationale, clinical evidence, application techniques and future prospects of growth factor use in implant dentistry.

Peri-implantitis represents a biofilm-associated pathologic condition characterized by inflammation and progressive bone loss around osseointegrated dental implants, which is a major risk to the survival of the implant. The etiology of peri-implantitis as a multifactorial process that includes microbial colonization, host susceptibility, biomechanical overload and systemic factors such as diabetes and smoking is analyzed in this systematic review. Preventive measures such as aggressive oral hygiene protocols, patient education and surface modification of implants are highlighted for their risk prevention potential. Management strategies involve both non-surgical interventions—debridement, local antibiotics, and laser phototherapy and surgery, resective and regenerative strategies to the severity of the disease. Comprehensive understanding of peri-implantitis pathogenesis and evidence-based treatment is essential in optimizing implant success and patient experience.

Dental implants have become a reliable solution for edentulism, yet bone limitations often necessitate alternative approaches such as short implants. This systematic review evaluates and compares the clinical outcomes and success rates of short dental implants (≤8 mm) versus standard-length implants (>8 mm) in various clinical scenarios. Data from multiple studies were analyzed to assess implant survival, marginal bone loss, prosthetic complications and long-term stability. The findings suggest that, when appropriately indicated, short implants demonstrate comparable success and survival rates to their longer counterparts, particularly in atrophic ridges where bone augmentation may be avoided. However, variations in surgical techniques, prosthetic protocols and patient-related factors can influence outcomes. Thus, short implants represent a viable, minimally invasive alternative, provided patient selection and clinical protocols are well-considered.