I hold a Canada Research Chair in the Environment and Genetics of Respiratory Diseases and Allergy. My research focuses on the identification of genetic risk factors associated with asthma and allergy including food allergy. I am interested in the identification of biological pathways involved in these diseases through the analyses of genetic variations. Furthermore, my research leverages the generation and integration of the “omics” data (i.e. genomics, transcriptomics, epigenomics) to better understand asthma pathogenesis. My work on the integration of these data allow to describe the genetic interactions underlying the association between specific genes and asthma as well as allergy. In addition to my research interest in asthma and allergy, I lead several projects on the identification of genetic determinants of rare diseases, particularly those which are prevalent in the Saguenay‒Lac St-Jean (SLSJ) population, recognized as a founder effect population. Mucolipidosis type II, agenesis and dysgenesis of the corpus callosum, epidermolysis bullosa simplex, and leigh syndrome French Canadian type are some of these targeted rare disease. The goals of my research on these orphan diseases are to identify causal mutations, understand disease etiologies, and develop effective therapies. Finally, my laboratory is equipped with cutting-edge technology and provides an inspiring environment for genetic research.