Model trees are an extension of regression trees that associate leaves with multiple regression models. In this paper, a method for the data-driven construction of model trees is presented, namely, the stepwise model tree induction (SMOTI) method. Its main characteristic is the induction of trees with two types of nodes: regression nodes, which perform only straight-line regression, and splitting nodes, which partition the feature space. The multiple linear model associated with each leaf is then built stepwise by combining straight-line regressions reported along the path from the root to the leaf. In this way, internal regression nodes contribute to the definition of multiple models and have a "global" effect, while straight-line regressions at leaves have only "local" effects. Experimental results on artificially generated data sets show that SMOTI outperforms two model tree induction systems, M5' and RETIS, in accuracy. Results on benchmark data sets used for studies on both regression and model trees show that SMOTI performs better than RETIS in accuracy, while it is not possible to draw statistically significant conclusions on the comparison with M5'. Model trees induced by SMOTI are generally simple and easily interpretable and their analysis often reveals interesting patterns.

In this paper, we tackle the problem of power prediction of several photovoltaic (PV) plants spread over an extended geographic area and connected to a power grid. The paper is intended to be a comprehensive study of one-day ahead forecast of PV energy production along several dimensions of analysis: 1) The consideration of the spatio-temporal autocorrelation, which characterizes geophysical phenomena, to obtain more accurate predictions. 2) The learning setting to be considered, i.e., using simple output prediction for each hour or structured output prediction for each day. 3) The learning algorithms: We compare artificial neural networks, most often used for PV prediction forecast, and regression trees for learning adaptive models. The results obtained on two PV power plant datasets show that: taking into account spatio/temporal autocorrelation is beneficial; the structured output prediction setting significantly outperforms the nonstructured output prediction setting; and regression trees provide better models than artificial neural networks.

MicroRNAs (miRNAs) are small non-coding RNAs which play a key role in the post-transcriptional regulation of many genes. Elucidating miRNA-regulated gene networks is crucial for the understanding of mechanisms and functions of miRNAs in many biological processes, such as cell proliferation, development, differentiation and cell homeostasis, as well as in many types of human tumors. To this aim, we have recently presented the biclustering method HOCCLUS2, for the discovery of miRNA regulatory networks. Experiments on predicted interactions revealed that the statistical and biological consistency of the obtained networks is negatively affected by the poor reliability of the output of miRNA target prediction algorithms. Recently, some learning approaches have been proposed to learn to combine the outputs of distinct prediction algorithms and improve their accuracy. However, the application of classical supervised learning algorithms presents two challenges: i) the presence of only positive examples in datasets of experimentally verified interactions and ii) unbalanced number of labeled and unlabeled examples.