Although electrospun nanofibers are expanding their potential commercial applications in various fields, the issue of energy savings, which are important for cost reduction and technological feasibility, has received little attention to date. In this study, a concentric spinneret with a solid Teflon-core rod was developed to implement an energy-saving electrospinning process. Ketoprofen and polyvinylpyrrolidone (PVP) were used as a model of a poorly water-soluble drug and a filament-forming matrix, respectively, to obtain nanofibrous films via traditional tube-based electrospinning and the proposed solid rod-based electrospinning method. The functional performances of the films were compared through in vitro drug dissolution experiments and ex vivo sublingual drug permeation tests. Results demonstrated that both types of nanofibrous films do not significantly differ in terms of medical applications. However, the new process required only 53.9% of the energy consumed by the traditional method. This achievement was realized by the introduction of several engineering improvements based on applied surface modifications, such as a less energy dispersive air-epoxy resin surface of the spinneret, a free liquid guiding without backward capillary force of the Teflon-core rod, and a smaller fluid–Teflon adhesive force. Other non-conductive materials could be explored to develop new spinnerets offering good engineering control and energy savings to obtain low-cost electrospun polymeric nanofibers.

As a new kind of water pollutant, antibiotics have encouraged researchers to develop new treatment technologies. Electrospun fiber membrane shows excellent benefits in antibiotic removal in water due to its advantages of large specific surface area, high porosity, good connectivity, easy surface modification and new functions. This review introduces the four aspects of electrospinning technology, namely, initial development history, working principle, influencing factors and process types. The preparation technologies of electrospun functional fiber membranes are then summarized. Finally, recent studies about antibiotic removal by electrospun functional fiber membrane are reviewed from three aspects, namely, adsorption, photocatalysis and biodegradation. Future research demand is also recommended.

This study presents a glucose biosensor based on electrospun core–sheath nanofibers. Two types of film were fabricated using different electrospinning procedures. Film F1 was composed solely of core–sheath nanofibers fabricated using a modified coaxial electrospinning process. Film F2 was a double-layer hybrid film fabricated through a sequential electrospinning and blending process. The bottom layer of F2 comprised core–sheath nanofibers fabricated using a modified process, in which pure polymethacrylate type A (Eudragit L100) was used as the core section and water-soluble lignin (WSL) and phenol were loaded as the sheath section. The top layer of F2 contained glucose oxidase (GOx) and gold nanoparticles, which were distributed throughout the polyvinylpyrrolidone K90 (PVP K90) nanofibers through a single-fluid blending electrospinning process. The study investigated the sequential electrospinning process in detail. The experimental results demonstrated that the F2 hybrid film had a higher degradation efficiency of β-D-glucose than F1, reaching a maximum of over 70% after 12 h within the concentration range of 10–40 mmol/L. The hybrid film F2 is used for colorimetric sensing of β-D-glucose in the range of 1–15 mmol/L. The solution exhibited a color that deepened gradually with an increase in β-D-glucose concentration. Electrospinning is flexible in creating structures for bio-cascade reactions, and the double-layer hybrid film can provide a simple template for developing other sensing nanomaterials.