Dr. Chi-Ren Shyu is Paul K. and Dianne Shumaker Professor of Biomedical Informatics and Director of the University of Missouri Institute for Data Science and Informatics. He received his PhD in Electrical and Computer Engineering from Purdue University. He has authored more than 160 refereed articles in bioinformatics, clinical informatics, geospatial informatics, and computer science. He is the PI of an NIH BD2K T32 training program in Data Science and One Health. He received the NSF CAREER award, multiple teaching and research awards at departmental and college levels, the MU Faculty Entrepreneur Award, and the University of Missouri President’s Leadership Award. Currently, his lab is developing eXplainable and Actionable AI (X2AI) and geospatial-enabled solutions for precision health research, including drug repositioning, geo-exposome understanding, digital clinical trials, and long-term health monitoring using electronic health records. He is a fellow of the American Medical Informatics Association.