Igor Nikitin

Prof. Igor Nikitin

K.G. Razumovsky Moscow State University of technologies and management (The First Cossack University)
orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 February 2022 in Applied Sciences
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Journal Article
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TSTanmay Sarkar
Tanmay Sarkar
MSMolla Salauddin
Molla Salauddin
KKKohima Kirtonia
Kohima Kirtonia
Siddhartha PatiSiddhartha Pati
Siddhartha Pati
MRMaksim B Rebezov
Maksim B Rebezov
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
The chemical composition of any food material can be analyzed well by employing various analytical techniques. The physical properties of food are no less important than chemical composition as results obtained from authentic measurement data are able to provide detailed information about the food. Several techniques have been used for years for this purpose but most of them are destructive in nature. The aim of this present study is to identify the emerging techniques that have been used by different researchers for the analysis of the physical characteristics of food. It is highly recommended to practice novel methods as these are non-destructive, extremely sophisticated, and provide results closer to true quantitative values. The physical properties are classified into different groups based on their characteristics. The concise view of conventional techniques mostly used to analyze food material are documented in this work.

20 June 2022 in Applied Sciences
Verified
Journal Article
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VGVictor V Gorbachev
Victor V Gorbachev
MNMarina A. Nikitina
Marina A. Nikitina
ДВДарья Велина
Дарья Велина
Sherzodkhon MutallibzodaSherzodkhon Mutallibzoda
Sherzodkhon Mutallibzoda
Vladimir V. NosovVladimir V. Nosov
Vladimir V. Nosov
Igor NikitinIgor Nikitin
Igor Nikitin
Using an artificial neural network (ANN), the values of the antiradical potential of 1315 items of food and agricultural raw materials were calculated. We used an ANN with the structure of a “multilayer perceptron” (MLP) and with the hyberbolic tangent (Tanh) as an activation function. Values reported in the United States Food and Nutrient Database for Dietary Studies (FNDDS) were taken as input to the analysis. When training the ANN, 60 parameters were used, such as the content of plastic substances, food calories, the amount of mineral components, vitamins, the composition of fatty acids and additional substances presented in this database. The analysis revealed correlations, namely, a direct relationship between the value of the antiradical potential (ARP) of food and the concentration of dietary fiber (r = 0.539) and a negative correlation between the value of ARP and the total calorie content of food (r = −0.432) at a significance level of p < 0.001 for both values. The average ARP value for 10 product groups within the 95% CI (confidence interval) was ≈23–28 equivalents (in terms of ascorbic acid) per 1 g of dry matter. The study also evaluated the range of average values of the daily recommended intake of food components (according to Food and Agriculture Organization—FAO, World Health Organization—WHO, Russia and the USA), which within the 95% CI, amounted to 23.41–28.98 equivalents per 1 g of dry weight. Based on the results of the study, it was found that the predicted ARP values depend not only on the type of raw materials and the method of their processing, but also on a number of other environmental and technological factors that make it difficult to obtain accurate values.

11 December 2025 in Diseases
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Journal Article
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EKEvgeniya Klein
Evgeniya Klein
ДВДарья Велина
Дарья Велина
Sherzodkhon MutallibzodaSherzodkhon Mutallibzoda
Sherzodkhon Mutallibzoda
СТСветлана Николаевна Тефикова
Светлана Николаевна Тефикова
ОООльга Александровна Орловцева
Ольга Александровна Орловцева
Igor NikitinIgor Nikitin
Igor Nikitin
Background: Type 2 diabetes mellitus (T2DM) remains one of the most significant public health problems, and its incidence rate is steadily increasing worldwide despite scientific and technological progress in the field of medicine. The focus of research in this area is gradually shifting from classic risk factors—such as obesity, sedentary lifestyle and genetic predisposition—toward additional, potentially modifiable contributors such as micronutrient imbalances; among them are disturbances in zinc homeostasis that may influence glucose metabolism and oxidative stress. Objective: This systematic review with narrative synthesis aims to examine the bidirectional relationship between zinc status and T2DM and to evaluate whether zinc screening and personalized nutritional support could contribute to comprehensive metabolic management. Methods: A literature search was conducted in the PubMed database and the Cochrane library for studies published between 2010 and 2024. Studies assessing zinc status or supplementation in relation to the risk, progression, or management of T2DM were included. Data were synthesized narratively, focusing on clinical and mechanistic evidence. Results: Thirty studies met the inclusion criteria. Evidence indicates that zinc imbalance (both deficiency and excess) is associated with T2DM risk and outcomes. Zinc deficiency may impair insulin synthesis and signaling, promote oxidative stress and inflammation, while excessive zinc intake may induce metabolic disturbances. T2DM itself may lead to reduced zinc status via altered absorption and increased excretion. While some studies suggest modest improvements in glycemic or lipid parameters following zinc supplementation, findings remain inconsistent and context-dependent. The prevalence of suboptimal zinc status in certain populations supports the rationale for targeted screening rather than routine supplementation. Conclusions: Zinc is mechanistically involved in insulin synthesis, antioxidant defense, and inflammation control, but current clinical evidence does not justify its use as a therapeutic agent in T2DM. Instead, assessment of zinc status and individualized correction of deficiency may represent a component of personalized nutritional support, particularly for patients with long disease duration, poor dietary quality, or genetic predispositions affecting zinc metabolism.

16 May 2024 in Toxics
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OROlga Rumiantseva
Olga Rumiantseva
VKViktor Komov
Viktor Komov
MKMikhail Nikolaevich Kutuzov
Mikhail Nikolaevich Kutuzov
HZHICHAM ZAROUAL
HICHAM ZAROUAL
KMKsenia Mizina
Ksenia Mizina
DVDaria VILKOVA
Daria VILKOVA
The consumption of fish in food may contain mercury, a harmful element and dangerous chemical detrimental to human health. The purpose of this study was to determine the mercury level in the hair of pregnant women with different fish intakes in their diets. The concentration of total mercury in hair was determined using an atomic absorption spectrometer. In this study, 98 pregnant women were invited to participate (aged from 18 to 48 years). The mean content of mercury in the hair of pregnant women in Northwestern Russia was 0.428 mg/kg (ranging from 0.018 to 3.1 mg/kg). As a result, 22% of women had mercury values above 0.58 mg/kg, which is considered dangerous for the fetus. The hair mercury concentration in a village area was higher than that in a city area (i.e., 0.548 mg/kg and 0.326 mg/kg). Moreover, the maximum level of mercury was noted for a group of pregnant women who consumed more than 5 kg/month of fish and fish products. Furthermore, the consumption of freshwater fish in the diet leads to a higher mercury content in the hair of pregnant women than the consumption of marine fish.

1 February 2021 in IOP Conference Series: Earth and Environmental Science
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NIN G Ivanova
N G Ivanova
Igor NikitinIgor Nikitin
Igor Nikitin
MKM V Klokonos
M V Klokonos
NBN A Berezina
N A Berezina
TBT A Bulavina
T A Bulavina
DGD A Guseva
D A Guseva
Dietary fiber is an essential component for the intestinal microflora. The state of the intestinal microflora is important for the human body, and is also necessary for reducing allergenicity and improving general well-being. Insufficient consumption of prebiotic components leads to a number of pathological conditions, ranging from intestinal disorders to intoxication of the entire body. Today, the market offers a wide range of confectionery products, the consumption of which is an integral part of the human diet, but they are characterized by low nutritional and high energy value. Improving the technology of confectionery products by introducing functional ingredients into the recipe, which improves the state of the intestinal microbiota, will allow a scientifically sound approach to solving the problem of the lack of bifidogenic confectionery products, improving their range and ensuring wide consumption in everyday life. The paper presents the results of research on the development of marshmallow technology of increased nutritional value. It is justified to replace part of the recipe amount of sugar with Jerusalem artichoke syrup as a source of inulin and milk whey used instead of organic acids and sodium lactate. To expand the prebiotic components, part of the Apple puree is replaced with a puree of black currant, blueberry and strawberry berries. The presented range of marshmallows is characterized by a reduced energy value, low sugar content, enriched with dietary fibers, B and C vitamins, potassium, calcium and iron. The storage capacity of the developed marshmallow was investigated, which showed a longer preservation of freshness due to the presence of whey in the formulation, which serves as a moisture-retaining component.

23 March 2022 in Foods
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Journal Article
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VGVictor V Gorbachev
Victor V Gorbachev
MKMaria Klokonos
Maria Klokonos
Sherzodkhon MutallibzodaSherzodkhon Mutallibzoda
Sherzodkhon Mutallibzoda
СТСветлана Николаевна Тефикова
Светлана Николаевна Тефикова
OOOlga Orlovtseva
Olga Orlovtseva
Igor NikitinIgor Nikitin
Igor Nikitin
Antiradical potential (ARP) is an important measure of food safety. In addition, it directly or indirectly affects the rate of occurrence of a number of human pathologies. Using a photocolorimetric analysis of DPPH (2,2-diphenyl-1-picrylhydrazyl) solutions, we estimated the antiradical potential of food raw materials, food concentrates, biologically active substances, and wild plants. We conducted approximately 1500 analyses of almost 100 food products selected from 11 food groups: vegetables, milk, meat, fish, cereals and bread, drinks (including tea and coffee), etc. With a confidence interval (CI) of 95%, the average values for animal products range from 15.87 to 18.70 ascorbic acid equivalents per gram of dry matter. For plant materials, the range is 474.54–501.50 equivalents when wild herbs are included and 385.02–408.83 equivalents without taking herbs into account. The antiradical potential of the biologically active substances we studied ranged from 706.84 to 847.77 equivalents per gram of dry matter, which makes it possible to use some of the components to repair products with low ARP values, for example, bread and baked goods, confectionery, milk and dairy products, carbonated drinks, and juice. In this study, a low ARP value is associated with a reduction in the shelf life of products and a deterioration in their organoleptic properties; therefore, we propose using ARP as an important reference for describing the quality of food products and raw food materials.