Objectives: This study was conducted to investigate alteration in blood parameters and their association with the presence, severity, and mortality of COVID-19 patients as the data on hematological abnormalities associated with the Pakistani COVID-19 patients is limited. Methodology: A double-centered, hospital-based comparative retrospective case study was conducted, to include all the admitted patients (n = 317) having COVID-19 Polymerase chain reaction (PCR) positive. The control group (n = 157) tested negative for COVID-19. Results: Of 317 admitted cases, the majority were males n = 198 (62.5%). Associated comorbidities, lower lymphocytes, platelets, and higher White blood cells, neutrophil, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were found in COVID-19 cases as compared to healthy controls (p < 0.001 for all). The biochemical parameters of cases including Ferritin, D-Dimer, CRP, IL-6, LDH, ALT, AST, and APTT also showed a statistically significant difference compared with standard values (p < 0.001 for all). However, their comparison with a severity level of the severe and non-severe groups showed significance for WBCs, neutrophils, NLR (p < 0.001 for all), and PLR (p = 0.06) only. Receiver operating characteristic curve analysis showed that NLR had the highest area under curve (0.84) followed by 1/lymphocyte (0.82), neutrophils (0.74), PLR (0.67),1/platelets (0.68) and WBC's (0.65). Comparison of cases and controls with recommended cut-off values derived from sensitivity and 1-specificity was also done (p < 0.001). Conclusion: Monitoring all the hematological and biochemical parameters including novel hemograms NLR, PLR can aid clinicians to identify potentially severe cases at early stages and initiate effective management in time which may reduce the overall mortality of COVID-19 patients.

Accompanied by false information, mass media content is hindering efforts to cope with the current outbreak. Although the World Health Organization and other concerned bodies are notified regarding misinformation, myths and rumors are highly prevalent. This paper aims to highlight the misinformation and its potential impacts during the Covid-19 by using the Systematic Review Approach. The researcher randomly selected n = 35 research articles published from 2015 to 2020, witnessing the misinformation as a major concern during previous endemics and the current Covid-19 pandemic. Myths and rumors through traditional and new media platforms cause Xenophobia, LGBT Rights violations, and psychological disorders among the masses. Despite the efforts made by the World Health Organization, much more is required to nullify the impacts of misinformation and Covid-19. Therefore, the researcher recommended improved global healthcare policies and strategies to counteract against misinformation to mitigate the impacts of Covid-19.

Child sexual abuse is a growing problem, representing an egregious abuse of power, trust, and authority with far-reaching implications for the victims. This review study highlights the intricate psychological impacts of child sexual abuse, addressing both short and long-term consequences. Existing literature highlights the deep impacts on the victims’ psychological health and well-being, necessitating an in-depth examination of the subject. Drawing from a sample of n = 19 research articles selected through stringent inclusion and exclusion criteria and the PRISMA approach, this study synthesizes results from publications spanning 2010 to 2022. The review reveals various detrimental impacts on the victims’ psychological well-being, including short-term consequences, i.e., isolation, bullying, stress, anxiety, and post-traumatic stress disorder (PTSD). Long-term effects encompass PTSD in later life, disrupted intimate relationships, social and emotional health concerns, revictimization, and more. In conclusion, the study emphasizes the lack of a definitive number of impacts, highlighting the need to discuss and raise awareness about child sexual abuse. This increased awareness is important for parents, guardians, and responsible authorities to effectively counteract these crimes against children. Also, providing emotional support to victims is important to mitigate the long-term impacts. The researchers offer implications and discuss limitations, providing an extensive overview and foundation for future research and interventions.