Harinder Singh

Dr. Harinder Singh

Department of Biological Sciences, Sunandan Divatia School of Science, NMIMS University, Mumbai-400056, India
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Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 August 2018 in Journal of Basic Microbiology
Verified
Journal Article
Closed access
Harinder SinghHarinder Singh
Harinder Singh


7 November 2018 in Molecular Biotechnology
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Journal Article
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AKAsmita Kamble
Asmita Kamble
SSSumana Srinivasan
Sumana Srinivasan
Harinder SinghHarinder Singh
Harinder Singh

11 August 2010 in Journal of Biosciences
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Journal Article
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Harinder SinghHarinder Singh
Harinder Singh
TFTonina Fernandes
Tonina Fernandes
SAShree Kumar Apte
Shree Kumar Apte

28 August 2014 in Journal of Microbiology and Biotechnology
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Journal Article
Closed access
Harinder SinghHarinder Singh
Harinder Singh
DADeepti Appukuttan
Deepti Appukuttan
SLSangyong Lim
Sangyong Lim
The present study shows that DR1114 (Hsp20), a small heat shock protein of the radiationresistant bacterium Deinococcus radiodurans, enhances tolerance to hydrogen peroxide (H2O2) stress when expressed in Escherichia coli. A protein profile comparison showed that E. coli cells overexpressing D. radiodurans Hsp20 (EC-pHsp20) activated the redox state proteins, thus maintaining redox homeostasis. The cells also showed increased expression of pseudouridine (psi) synthases, which are important to the stability and proper functioning of structural RNA molecules. We found that the D. radiodurans mutant strain, which lacks a psi synthase (DR0896), was more sensitive to H2O2 stress than wild type. These suggest that an increased expression of proteins involved in the control of redox state homeostasis along with more stable ribosomal function may explain the improved tolerance of EC-pHsp20 to H2O2 stress.

1 November 2008 in Desalination
Verified
Journal Article
Closed access
MAM. Anitha
M. Anitha
Harinder SinghHarinder Singh
Harinder Singh