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Matthias Kliegel
Department of Psychology, University of Geneva, Genève 4, Switzerland

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Short Biography

Prof. Matthias Kliegel is a lifespan developmental psychologist with a focus on cognitive aging who has received his PhD in psychology from the University of Heidelberg in 2002 and his habilitation from the University of Zurich in 2005. In 2007, he was appointed Full Professor and Chair of Lifespan Developmental Psychology at the University of Dresden. Since 2011 Matthias Kliegel has been working as Full Professor and Chair of Cognitive Aging at the University of Geneva, where he also is the director of the University of Geneva's Interfaculty Center of Gerontology (CIGEV). In 2017, he was elected president of the Swiss Psychological Society. His research is concerned with healthy aging and the development and plasticity of higher order cognitive functions such as intentional behavior and cognitive control as well as their neuro-cognitive mechanisms across the human lifespan. He has received numerous awards (e.g., Vontobel Aging Research Award, Leenaards Prize), research grants (e.g., from the Swiss National Science Foundation, German Research Foundation or Australian Research Council) and has published more than 300 research papers. Alumni from Matthias Kliegel's research group hold academic positions allover Europe and in North America.

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Correction
Published: 29 June 2021 in International Archives of Occupational and Environmental Health
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Johannes Wendsche; Andreas Ihle; Jürgen Wegge; Marlene Sophie Penz; Clemens Kirschbaum; Matthias Kliegel. Correction to: Prospective associations between burnout symptomatology and hair cortisol. International Archives of Occupational and Environmental Health 2021, 1 -1.

AMA Style

Johannes Wendsche, Andreas Ihle, Jürgen Wegge, Marlene Sophie Penz, Clemens Kirschbaum, Matthias Kliegel. Correction to: Prospective associations between burnout symptomatology and hair cortisol. International Archives of Occupational and Environmental Health. 2021; ():1-1.

Chicago/Turabian Style

Johannes Wendsche; Andreas Ihle; Jürgen Wegge; Marlene Sophie Penz; Clemens Kirschbaum; Matthias Kliegel. 2021. "Correction to: Prospective associations between burnout symptomatology and hair cortisol." International Archives of Occupational and Environmental Health , no. : 1-1.

Review
Published: 23 June 2021 in Brain Sciences
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Physical activity (PA) may influence the secretion of neurotransmitters and thereby have positive consequences for an individual’s vulnerability (i.e., reducing anxiety and depressive symptoms). This systematic review aims to analyse the potential bidirectional effects of exercise on dopamine from young adulthood to old age. The article search was conducted in PubMed, Scopus, and Web of Science in December 2020. The inclusion criteria were longitudinal and experimental study design; outcomes included dopamine and exercise; effect of exercise on dopamine and vice versa; adults; and articles published in English, Portuguese, or Spanish. Fifteen articles were included in the review. We observed robust findings concerning the potential effects of PA on dopamine, which notably seem to be observable across a wide range of participants characteristics (including age and sex), a variety of PA characteristics, and a broad set of methods to analyse dopamine. By contrast, regarding the potential effects of dopamine on PA, findings were mixed across studies. Thus, there are robust effects of physical exercise on dopamine. These findings further strengthen the idea that innovative approaches could include PA interventions for treating and preventing mental disorders. Therefore, it seems that PA is a potential alternative to deal with mental health issues.

ACS Style

Adilson Marques; Priscila Marconcin; André Werneck; Gerson Ferrari; Élvio Gouveia; Matthias Kliegel; Miguel Peralta; Andreas Ihle. Bidirectional Association between Physical Activity and Dopamine Across Adulthood—A Systematic Review. Brain Sciences 2021, 11, 829 .

AMA Style

Adilson Marques, Priscila Marconcin, André Werneck, Gerson Ferrari, Élvio Gouveia, Matthias Kliegel, Miguel Peralta, Andreas Ihle. Bidirectional Association between Physical Activity and Dopamine Across Adulthood—A Systematic Review. Brain Sciences. 2021; 11 (7):829.

Chicago/Turabian Style

Adilson Marques; Priscila Marconcin; André Werneck; Gerson Ferrari; Élvio Gouveia; Matthias Kliegel; Miguel Peralta; Andreas Ihle. 2021. "Bidirectional Association between Physical Activity and Dopamine Across Adulthood—A Systematic Review." Brain Sciences 11, no. 7: 829.

Original paper
Published: 05 June 2021 in Mindfulness
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Objectives Several studies have investigated the relationship between contemplative approaches and psychobiological stress response; however, this area of research is still new, the mechanisms of the relationship between the stress response attenuation and contemplative training have not been fully delineated, and little is known about the effects of contemplative practice on the ways psychological stress is experienced. This study aimed to explore the first-person experience of psychological stress in meditation practitioners. Methods We conducted short semi-structured interviews with twenty-five meditation practitioners and twenty meditation-naïve controls immediately after they had undergone a laboratory task (the Trier Social Stress Test). A mixed-method approach was used to analyze the interviews. Thematic analysis was combined with descriptive statistics of the qualitative information that had been converted to quantitative data. Results Experiences instantiating main themes were identified as follows: (1) primary experiences encountered, describing the most salient experiences associated with the task; (2) reasons for stress, delineating the analyses of why the task was stressful; (3) affect, dealing with emotional experiences during the task; (4) emotion regulation; and (5) attention allocation describing regulatory strategies employed by the participants. Responses to subjective stress experience in meditation practitioners included use of humor, presence of positive affect, combinations of different types of emotion regulation strategies, and adaptive attention allocation. Conclusions This study elucidates particularities of meditators’ subjective experience of psychological stress, provides new insights on the mechanisms of meditation effect on the stress response, and proposes new directions for research.

ACS Style

Liudmila Gamaiunova; Pierre-Yves Brandt; Matthias Kliegel. Contemplative Training and Psychological Stress: an Analysis of First-person Accounts. Mindfulness 2021, 1 -16.

AMA Style

Liudmila Gamaiunova, Pierre-Yves Brandt, Matthias Kliegel. Contemplative Training and Psychological Stress: an Analysis of First-person Accounts. Mindfulness. 2021; ():1-16.

Chicago/Turabian Style

Liudmila Gamaiunova; Pierre-Yves Brandt; Matthias Kliegel. 2021. "Contemplative Training and Psychological Stress: an Analysis of First-person Accounts." Mindfulness , no. : 1-16.

Journal article
Published: 16 February 2021 in Neurobiology of Aging
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Given the controversy about the impact of modifiable risk factors on mood and cognition in ageing, we sought to investigate the associations between cardio-vascular risk, mental health, cognitive performance and brain anatomy in mid- to old age. We analyzed a set of risk factors together with multi-parameter magnetic resonance imaging (MRI) in the CoLaus|PsyCoLaus cohort (n > 1200). Cardio-vascular risk was associated with differences in brain tissue properties – myelin, free tissue water, iron content – and regional brain volumes that we interpret in the context of micro-vascular hypoxic lesions and neurodegeneration. The interaction between clinical subtypes of major depressive disorder and cardio-vascular risk factors showed differential associations with brain structure depending on individuals’ lifetime trajectory. There was a negative correlation between melancholic depression, anxiety and MRI markers of myelin and iron content in the hippocampus and anterior cingulate. Verbal memory and verbal fluency performance were positively correlated with left amygdala volumes. The concomitant analysis of brain morphometry and tissue properties allowed for a neuro-biological interpretation of the link between modifiable risk factors and brain health.

ACS Style

Olga Trofimova; Leyla Loued-Khenissi; Giulia DiDomenicantonio; Antoine Lutti; Matthias Kliegel; Silvia Stringhini; Pedro Marques-Vidal; Peter Vollenweider; Gérard Waeber; Martin Preisig; Ferath Kherif; Bogdan Draganski. Brain tissue properties link cardio-vascular risk factors, mood and cognitive performance in the CoLaus|PsyCoLaus epidemiological cohort. Neurobiology of Aging 2021, 102, 50 -63.

AMA Style

Olga Trofimova, Leyla Loued-Khenissi, Giulia DiDomenicantonio, Antoine Lutti, Matthias Kliegel, Silvia Stringhini, Pedro Marques-Vidal, Peter Vollenweider, Gérard Waeber, Martin Preisig, Ferath Kherif, Bogdan Draganski. Brain tissue properties link cardio-vascular risk factors, mood and cognitive performance in the CoLaus|PsyCoLaus epidemiological cohort. Neurobiology of Aging. 2021; 102 ():50-63.

Chicago/Turabian Style

Olga Trofimova; Leyla Loued-Khenissi; Giulia DiDomenicantonio; Antoine Lutti; Matthias Kliegel; Silvia Stringhini; Pedro Marques-Vidal; Peter Vollenweider; Gérard Waeber; Martin Preisig; Ferath Kherif; Bogdan Draganski. 2021. "Brain tissue properties link cardio-vascular risk factors, mood and cognitive performance in the CoLaus|PsyCoLaus epidemiological cohort." Neurobiology of Aging 102, no. : 50-63.

Journal article
Published: 04 February 2021 in Psychology and Aging
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Prospective memory (PM) is a critical determinant of whether a person is able to lead an independent life. Because PM declines in late adulthood, an important question is therefore whether, and if so, which types, of PM interventions might lead to meaningful benefits. In the present study, we randomly assigned older adults to one of four conditions, in three of which participants received a structured PM intervention (Restorative, Compensatory, and Combined Restorative and Compensatory); the fourth was an Active Control condition. The results showed that there were significant gains on the PM training task used for both the Restorative and Combined conditions. We then analyzed change in PM tasks that were independent of the PM training task (Near Transfer). Only the Combined condition led to post-training improvement. Finally, we analyzed performance on measures of untrained cognitive abilities and everyday functioning: Far transfer effects were not evident for any intervention. These data align with prior literature in showing that interventions that target a single cognitive ability do not reliably generate far transfer effects, and additionally extend our understanding of these effects in two important ways. Firstly, they indicate that, even when the memory challenges that older adults are most concerned about are the direct target of restorative training, transfer effects to untrained cognitive domains may be difficult to achieve. Secondly, they indicate that for older adults whose primary goal is to enhance PM function, combining Restorative and Compensatory approaches is an effective approach. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

ACS Style

Julie D. Henry; Alexandra Hering; Simon Haines; Sarah A. Grainger; Nick Koleits; Skye McLennan; Rachel Pelly; Colleen Doyle; Nathan S. Rose; Matthias Kliegel; Peter G. Rendell. Acting with the future in mind: Testing competing prospective memory interventions. Psychology and Aging 2021, 1 .

AMA Style

Julie D. Henry, Alexandra Hering, Simon Haines, Sarah A. Grainger, Nick Koleits, Skye McLennan, Rachel Pelly, Colleen Doyle, Nathan S. Rose, Matthias Kliegel, Peter G. Rendell. Acting with the future in mind: Testing competing prospective memory interventions. Psychology and Aging. 2021; ():1.

Chicago/Turabian Style

Julie D. Henry; Alexandra Hering; Simon Haines; Sarah A. Grainger; Nick Koleits; Skye McLennan; Rachel Pelly; Colleen Doyle; Nathan S. Rose; Matthias Kliegel; Peter G. Rendell. 2021. "Acting with the future in mind: Testing competing prospective memory interventions." Psychology and Aging , no. : 1.

Journal article
Published: 01 February 2021 in International Journal of Environmental Research and Public Health
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Metabolic syndrome has been considered a factor of vulnerability and a major public health problem because it increases the risk of cardiovascular disease and type 2 diabetes. The present study from Amazonas, Brazil aimed to estimate the prevalence of the individual and general components of metabolic syndrome in adults and older adults and identify the independent predictors of metabolic syndrome. The sample of the present cross-sectional study comprised 942 participants (590 women), with a mean age of 59.8 ± 19.7 (range: 17.5 to 91.8). Blood pressure in men (62.5%), abdominal obesity in women (67.3%), and lower high-density lipoprotein cholesterol (HDL-C) in both (52.2% in men and 65.0% in women) were the most prevalent individual risk factors for metabolic syndrome. Women had a higher prevalence of abdominal obesity (p < 0.001), low HDL-C (p < 0.001), and metabolic syndrome (p < 0.001) than men; however, opposite results were seen in men for blood pressure (p < 0.001). The overall prevalence of metabolic syndrome was 47.5%. Advanced age, being female, having a higher body mass index, and a having lower educational level independently increased the odds of metabolic syndrome. Due to the association of metabolic syndrome with deterioration of health status and increased vulnerability, this study sustains the need for early public health interventions in the Amazonas region.

ACS Style

Élvio Gouveia; Bruna Gouveia; Adilson Marques; Miguel Peralta; Cíntia França; Alex Lima; Alderlane Campos; Jefferson Jurema; Matthias Kliegel; Andreas Ihle. Predictors of Metabolic Syndrome in Adults and Older Adults from Amazonas, Brazil. International Journal of Environmental Research and Public Health 2021, 18, 1303 .

AMA Style

Élvio Gouveia, Bruna Gouveia, Adilson Marques, Miguel Peralta, Cíntia França, Alex Lima, Alderlane Campos, Jefferson Jurema, Matthias Kliegel, Andreas Ihle. Predictors of Metabolic Syndrome in Adults and Older Adults from Amazonas, Brazil. International Journal of Environmental Research and Public Health. 2021; 18 (3):1303.

Chicago/Turabian Style

Élvio Gouveia; Bruna Gouveia; Adilson Marques; Miguel Peralta; Cíntia França; Alex Lima; Alderlane Campos; Jefferson Jurema; Matthias Kliegel; Andreas Ihle. 2021. "Predictors of Metabolic Syndrome in Adults and Older Adults from Amazonas, Brazil." International Journal of Environmental Research and Public Health 18, no. 3: 1303.

Journal article
Published: 21 January 2021 in Children
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This study aimed to test an observational momentary time sampling tool to estimate in-class moderate-to-vigorous physical activity (MVPA), in terms of validity, reliability and agreement between observational momentary time sampling and accelerometry, and to develop a regression equation to estimate MVPA from observational momentary time sampling. The sample comprised 78 pupils (38 girls), mean age 14.0 ± 1.1 years. Measurements were taken in three similar Physical Education classes, on three different days. To monitor MVPA, we applied the observational momentary time sampling method. Students wore an ActiGraph GT3X+ accelerometer. Reliabilities were determined by the intraclass correlations, the agreement between methods was analyzed using the Bland–Altman method, and a multiple regression analysis was performed to estimate the equation. The observational momentary time sampling showed good reliability across time (0.59 < r < 0.72, p < 0.001). It was significantly correlated with accelerometry (r = 0.51, p < 0.001). The MVPA assessed via accelerometer could be predicted from the following equation: Y = 44.3 + 0.47⋅(MVPA observational momentary time sampling method) + 8.0⋅(sex; with 0 = girls and 1 = boys). This observational momentary time sampling method is a stable and reliable tool to estimate MVPA. A regression equation using the score of observational momentary time sampling and sex can be used to better estimate the real MVPA.

ACS Style

Élvio Gouveia; Bruna Gouveia; Adilson Marques; Helder Lopes; Ana Rodrigues; Tomás Quintal; Marcelo Pestana; Miguel Peralta; Matthias Kliegel; Andreas Ihle. Estimation of Engagement in Moderate-to-Vigorous Physical Activity from Direct Observation: A Proposal for School Physical Education. Children 2021, 8, 67 .

AMA Style

Élvio Gouveia, Bruna Gouveia, Adilson Marques, Helder Lopes, Ana Rodrigues, Tomás Quintal, Marcelo Pestana, Miguel Peralta, Matthias Kliegel, Andreas Ihle. Estimation of Engagement in Moderate-to-Vigorous Physical Activity from Direct Observation: A Proposal for School Physical Education. Children. 2021; 8 (2):67.

Chicago/Turabian Style

Élvio Gouveia; Bruna Gouveia; Adilson Marques; Helder Lopes; Ana Rodrigues; Tomás Quintal; Marcelo Pestana; Miguel Peralta; Matthias Kliegel; Andreas Ihle. 2021. "Estimation of Engagement in Moderate-to-Vigorous Physical Activity from Direct Observation: A Proposal for School Physical Education." Children 8, no. 2: 67.

Journal article
Published: 06 January 2021 in Brain Sciences
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While objective memory performance in older adults was primarily shown to be affected by education as indicator of life course socioeconomic conditions, other life course socioeconomic conditions seem to relate to subjective memory complaints. However, studies differ in which life course stages were investigated. Moreover, studies have explored these effects in an isolated way, but have not yet investigated their unique effect when considering several stages of the life course simultaneously. This study, therefore, examined the respective influence of socioeconomic conditions from childhood up to late-life on prospective memory (PM) performance as an objective indicator of everyday memory as well as on subjective memory complaints (SMC) in older age using structural equation modeling. Data came from two waves of the Vivre-Leben-Vivere aging study (n=993, Mage=80.56). The results indicate that only socioeconomic conditions in adulthood significantly predicted late-life PM performance. PM performance was also predicted by age and self-rated health. In contrast, SMC in older age were not predicted by socioeconomic conditions at any stage of the life course but were predicted by level of depression. In line with the cognitive reserve hypothesis, present results highlight the significance of education and occupation (adulthood socioeconomic conditions) for cognitive functioning in later life.

ACS Style

Morgane Künzi; Emilie Joly-Burra; Sascha Zuber; Maximilian Haas; Doriana Tinello; Chloé Da Silva Coelho; Alexandra Hering; Andreas Ihle; Gianvito Laera; Greta Mikneviciute; Silvia Stringhini; Bogdan Draganski; Matthias Kliegel; Nicola Ballhausen. The Relationship between Life Course Socioeconomic Conditions and Objective and Subjective Memory in Older Age. Brain Sciences 2021, 11, 61 .

AMA Style

Morgane Künzi, Emilie Joly-Burra, Sascha Zuber, Maximilian Haas, Doriana Tinello, Chloé Da Silva Coelho, Alexandra Hering, Andreas Ihle, Gianvito Laera, Greta Mikneviciute, Silvia Stringhini, Bogdan Draganski, Matthias Kliegel, Nicola Ballhausen. The Relationship between Life Course Socioeconomic Conditions and Objective and Subjective Memory in Older Age. Brain Sciences. 2021; 11 (1):61.

Chicago/Turabian Style

Morgane Künzi; Emilie Joly-Burra; Sascha Zuber; Maximilian Haas; Doriana Tinello; Chloé Da Silva Coelho; Alexandra Hering; Andreas Ihle; Gianvito Laera; Greta Mikneviciute; Silvia Stringhini; Bogdan Draganski; Matthias Kliegel; Nicola Ballhausen. 2021. "The Relationship between Life Course Socioeconomic Conditions and Objective and Subjective Memory in Older Age." Brain Sciences 11, no. 1: 61.

Journal article
Published: 01 December 2020 in Psychology and Aging
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Julie D. Henry; Gill Terrett; Sarah A. Grainger; Nathan S. Rose; Matthias Kliegel; Melissa Bugge; Clare Ryrie; Peter G. Rendell. Implementation intentions and prospective memory function in late adulthood. Psychology and Aging 2020, 35, 1105 -1114.

AMA Style

Julie D. Henry, Gill Terrett, Sarah A. Grainger, Nathan S. Rose, Matthias Kliegel, Melissa Bugge, Clare Ryrie, Peter G. Rendell. Implementation intentions and prospective memory function in late adulthood. Psychology and Aging. 2020; 35 (8):1105-1114.

Chicago/Turabian Style

Julie D. Henry; Gill Terrett; Sarah A. Grainger; Nathan S. Rose; Matthias Kliegel; Melissa Bugge; Clare Ryrie; Peter G. Rendell. 2020. "Implementation intentions and prospective memory function in late adulthood." Psychology and Aging 35, no. 8: 1105-1114.

Journal article
Published: 26 October 2020 in Sustainability
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We investigated the longitudinal relationship between physical fitness (flexibility, functional strength, and running speed-agility components) and subsequent change in academic achievement across one school year. We also examined whether this longitudinal relationship differed as a function of pupils’ age, controlling for sex, body mass index, and socioeconomic status. Academic achievement in terms of marks in Portuguese and mathematics was recorded from 142 pupils (M = 14.59 years; SD = 1.99, range 11–18), between autumn 2017 and summer 2018. The physical fitness components, including flexibility, functional strength, and running speed-agility, were assessed at the baseline (i.e., at the beginning of the school year). Latent change score modelling revealed that higher physical fitness level at baseline significantly predicted a subsequent improvement in academic achievement across the school year. This longitudinal relationship was significantly stronger in younger compared to older pupils. Physical fitness and its interaction with age predicted 45.7% of the variance in the change in academic achievement. In conclusion, a better physical fitness profile including flexibility, functional strength, and running speed-agility explains a subsequent improvement in academic achievement. This longitudinal relationship seems to be age-dependent.

ACS Style

Élvio Gouveia; Bruna Gouveia; Adilson Marques; Helder Lopes; Ana Rodrigues; Miguel Peralta; Matthias Kliegel; Andreas Ihle. Physical Fitness Predicts Subsequent Improvement in Academic Achievement: Differential Patterns Depending on Pupils’ Age. Sustainability 2020, 12, 8874 .

AMA Style

Élvio Gouveia, Bruna Gouveia, Adilson Marques, Helder Lopes, Ana Rodrigues, Miguel Peralta, Matthias Kliegel, Andreas Ihle. Physical Fitness Predicts Subsequent Improvement in Academic Achievement: Differential Patterns Depending on Pupils’ Age. Sustainability. 2020; 12 (21):8874.

Chicago/Turabian Style

Élvio Gouveia; Bruna Gouveia; Adilson Marques; Helder Lopes; Ana Rodrigues; Miguel Peralta; Matthias Kliegel; Andreas Ihle. 2020. "Physical Fitness Predicts Subsequent Improvement in Academic Achievement: Differential Patterns Depending on Pupils’ Age." Sustainability 12, no. 21: 8874.

Journal article
Published: 01 July 2020 in European Psychologist
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Frieder R. Lang; Isabelle Albert; Matthias Kliegel. Psychology and Aging: European Perspectives. European Psychologist 2020, 25, 159 -161.

AMA Style

Frieder R. Lang, Isabelle Albert, Matthias Kliegel. Psychology and Aging: European Perspectives. European Psychologist. 2020; 25 (3):159-161.

Chicago/Turabian Style

Frieder R. Lang; Isabelle Albert; Matthias Kliegel. 2020. "Psychology and Aging: European Perspectives." European Psychologist 25, no. 3: 159-161.

Original research article
Published: 16 June 2020 in Frontiers in Neuroscience
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This cluster randomized controlled trial provides evidence that focused musical instrumental practice, in comparison to traditional sensitization to music, provokes multiple transfer effects in the cognitive and sensorimotor domain. Over the last 2 years of primary school (10–12 years old), 69 children received group music instruction by professional musicians twice a week as part of the regular school curriculum. The intervention group learned to play string instruments, whereas the control group (i.e., peers in parallel classes) was sensitized to music via listening, theory and some practice. Broad benefits manifested in the intervention group as compared to the control group for working memory, attention, processing speed, cognitive flexibility, matrix reasoning, sensorimotor hand function, and bimanual coordination Apparently, learning to play a complex instrument in a dynamic group setting impacts development much stronger than classical sensitization to music. Our results therefore highlight the added value of intensive musical instrumental training in a group setting within the school curriculum. These results encourage general implementation of such training in public primary schools, thus better preparing children for secondary school and for daily living activities.

ACS Style

Clara E. James; Sascha Zuber; Elise Dupuis-Lozeron; Laura Abdili; Diane Gervaise; Matthias Kliegel. Formal String Instrument Training in a Class Setting Enhances Cognitive and Sensorimotor Development of Primary School Children. Frontiers in Neuroscience 2020, 14, 567 .

AMA Style

Clara E. James, Sascha Zuber, Elise Dupuis-Lozeron, Laura Abdili, Diane Gervaise, Matthias Kliegel. Formal String Instrument Training in a Class Setting Enhances Cognitive and Sensorimotor Development of Primary School Children. Frontiers in Neuroscience. 2020; 14 ():567.

Chicago/Turabian Style

Clara E. James; Sascha Zuber; Elise Dupuis-Lozeron; Laura Abdili; Diane Gervaise; Matthias Kliegel. 2020. "Formal String Instrument Training in a Class Setting Enhances Cognitive and Sensorimotor Development of Primary School Children." Frontiers in Neuroscience 14, no. : 567.

Other
Published: 05 June 2020
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Socioeconomic status (SES) plays a significant role in health and disease. At the same time, early-life conditions affect neural function and structure, suggesting the brain may be a conduit for the biological embedding of SES. Here, we investigate the neural signatures of SES in a large-scale population cohort aged 45–85 years. We assess both grey matter volume (GMV) and magnetization transfer (MT) saturation, indicative of myelin content. Higher SES in childhood and adulthood associated with more GMV in several brain regions, including postcentral and temporal gyri, cuneus, and cerebellum, while low SES correlated with larger entorhinal cortex volume. High childhood SES was linked to more widespread GMV differences and higher myelin content in the sensorimotor network while low SES correlated to myelin content in the temporal lobe. Crucially, childhood SES differences in adult brains persisted even after controlling for adult SES, highlighting the unique contribution of early-life conditions to neural status in older age, independent of later changes in SES. These findings inform on the biological underpinnings of social inequality, particularly as it pertains to early-life conditions.

ACS Style

Leyla Loued-Khenissi; Olga Trofimova; Peter Vollenweider; Pedro Marques-Vidal; Martin Preisig; Antoine Lutti; Matthias Kliegel; Carmen Sandi; Ferhat Kherif; Silvia Stringhini; Bogdan Draganski. The Inequality of Neural Destiny: Signatures of Life course Socioeconomic Conditions in Brain Myelination and Grey Matter Volume. 2020, 1 .

AMA Style

Leyla Loued-Khenissi, Olga Trofimova, Peter Vollenweider, Pedro Marques-Vidal, Martin Preisig, Antoine Lutti, Matthias Kliegel, Carmen Sandi, Ferhat Kherif, Silvia Stringhini, Bogdan Draganski. The Inequality of Neural Destiny: Signatures of Life course Socioeconomic Conditions in Brain Myelination and Grey Matter Volume. . 2020; ():1.

Chicago/Turabian Style

Leyla Loued-Khenissi; Olga Trofimova; Peter Vollenweider; Pedro Marques-Vidal; Martin Preisig; Antoine Lutti; Matthias Kliegel; Carmen Sandi; Ferhat Kherif; Silvia Stringhini; Bogdan Draganski. 2020. "The Inequality of Neural Destiny: Signatures of Life course Socioeconomic Conditions in Brain Myelination and Grey Matter Volume." , no. : 1.

Original article
Published: 13 March 2020 in International Archives of Occupational and Environmental Health
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Burnout is a stress-related, psychological syndrome due to high levels of job stressors. It has been found to be related to impairments of well-being, health, and job outcomes. Alterations of glucocorticoid secretion might be a mechanism explaining the linkage between burnout and reduced psychophysical functioning. Regarding hair cortisol as indicator this assumption, so far, has been only examined in cross-sectional studies. Therefore, we aimed to compare cross-sectional and prospective associations between different burnout symptoms and hair cortisol, additionally investigating potential nonlinear associations. The prospective study sample comprises 194 employees (95% nurses) from German geriatric care. We assessed burnout symptoms at baseline (t1) and 6 months later (t2) and collected hair samples for cortisol analyses at t2. We found significant cross-sectional and prospective nonlinear (i.e., exponential) but not linear relationships between an aggregated measure of the burnout subscales emotional exhaustion, cynicism, and reduced efficacy and hair cortisol, even after adjusting for BMI and depressive mood. None of the single subscales of burnout was related to hair cortisol after adjusting for confounders. Our findings further support the assumption that accumulated burnout symptoms and hypercorticolism are positively related.

ACS Style

Johannes Wendsche; Andreas Ihle; Jürgen Wegge; Marlene Sophie Penz; Clemens Kirschbaum; Matthias Kliegel. Prospective associations between burnout symptomatology and hair cortisol. International Archives of Occupational and Environmental Health 2020, 93, 779 -788.

AMA Style

Johannes Wendsche, Andreas Ihle, Jürgen Wegge, Marlene Sophie Penz, Clemens Kirschbaum, Matthias Kliegel. Prospective associations between burnout symptomatology and hair cortisol. International Archives of Occupational and Environmental Health. 2020; 93 (6):779-788.

Chicago/Turabian Style

Johannes Wendsche; Andreas Ihle; Jürgen Wegge; Marlene Sophie Penz; Clemens Kirschbaum; Matthias Kliegel. 2020. "Prospective associations between burnout symptomatology and hair cortisol." International Archives of Occupational and Environmental Health 93, no. 6: 779-788.

Preprint content
Published: 04 November 2019
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This randomized controlled trial shows for the first time that focused musical instrumental practice as compared to traditional sensitization to music provokes robust cognitive and sensorimotor transfer effects. Over the last two years of primary school (10-12-year-old children), sixty-nine children received biweekly musical instruction by professional musicians within the regular school curriculum. The intervention group learned to play string instruments, whereas the control group, peers in parallel classes, was sensitized to music via listening, theory, and some practice. Broad benefits manifested in the intervention group as compared to the control group for working memory, attention, processing speed, cognitive flexibility, matrix reasoning, sensorimotor hand function and bimanual coordination Apparently, learning to play a complex instrument in a dynamic group setting impacts development much stronger than classical sensitization to music. Our results therefore highlight the added value of intensive musical instrumental training in a group setting, encouraging general implementation in public primary schools, better preparing children for secondary school and for daily living activities.Highlights-Music practice produces multiple cognitive transfer effects in school children-Making music causes stronger cognitive benefits than sensitization to music-Music practice in a class setting improves executive functions and abstract thinking-Playing string instruments enhances fine manual dexterity and bimanual coordination

ACS Style

Clara E. James; Sascha Zuber; Elise Dupuis-Lozeron; Laura Abdili; Diane Gervaise; Matthias Kliegel. Formal string instrument training in a class setting enhances cognitive and sensorimotor development of primary school children. 2019, 829077 .

AMA Style

Clara E. James, Sascha Zuber, Elise Dupuis-Lozeron, Laura Abdili, Diane Gervaise, Matthias Kliegel. Formal string instrument training in a class setting enhances cognitive and sensorimotor development of primary school children. . 2019; ():829077.

Chicago/Turabian Style

Clara E. James; Sascha Zuber; Elise Dupuis-Lozeron; Laura Abdili; Diane Gervaise; Matthias Kliegel. 2019. "Formal string instrument training in a class setting enhances cognitive and sensorimotor development of primary school children." , no. : 829077.

Journal article
Published: 01 June 2019 in Psychology & Neuroscience
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Sascha Zuber; Andreas Ihle; Vanessa M. Loaiza; Katharina M. Schnitzspahn; Christoph Stahl; Louise H. Phillips; Christoph P. Kaller; Matthias Kliegel. Explaining age differences in working memory: The role of updating, inhibition, and shifting. Psychology & Neuroscience 2019, 12, 191 -208.

AMA Style

Sascha Zuber, Andreas Ihle, Vanessa M. Loaiza, Katharina M. Schnitzspahn, Christoph Stahl, Louise H. Phillips, Christoph P. Kaller, Matthias Kliegel. Explaining age differences in working memory: The role of updating, inhibition, and shifting. Psychology & Neuroscience. 2019; 12 (2):191-208.

Chicago/Turabian Style

Sascha Zuber; Andreas Ihle; Vanessa M. Loaiza; Katharina M. Schnitzspahn; Christoph Stahl; Louise H. Phillips; Christoph P. Kaller; Matthias Kliegel. 2019. "Explaining age differences in working memory: The role of updating, inhibition, and shifting." Psychology & Neuroscience 12, no. 2: 191-208.

Journal article
Published: 01 June 2019 in Psychology & Neuroscience
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Julia Sauter; Eric Widmer; Andreas Ihle; Matthias Kliegel. The association of leisure activities in middle adulthood with cognitive performance in old age: Social capital mediates cognitive reserve effects. Psychology & Neuroscience 2019, 12, 236 -246.

AMA Style

Julia Sauter, Eric Widmer, Andreas Ihle, Matthias Kliegel. The association of leisure activities in middle adulthood with cognitive performance in old age: Social capital mediates cognitive reserve effects. Psychology & Neuroscience. 2019; 12 (2):236-246.

Chicago/Turabian Style

Julia Sauter; Eric Widmer; Andreas Ihle; Matthias Kliegel. 2019. "The association of leisure activities in middle adulthood with cognitive performance in old age: Social capital mediates cognitive reserve effects." Psychology & Neuroscience 12, no. 2: 236-246.

Journal article
Published: 01 February 2019 in Neuropsychology
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Late-life leisure activity participation may predict later cognitive status in terms of TMT performance, but individuals may markedly differ with respect to such effects. Implications for current cognitive reserve and neuropsychological aging research are discussed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

ACS Style

Andreas Ihle; Delphine Fagot; Fanny Vallet; Nicola Ballhausen; Nathalie Mella; Marie Baeriswyl; Julia Sauter; Michel Oris; Jürgen Maurer; Matthias Kliegel. Cross-lagged relation of leisure activity participation to Trail Making Test performance 6 years later: Differential patterns in old age and very old age. Neuropsychology 2019, 33, 234 -244.

AMA Style

Andreas Ihle, Delphine Fagot, Fanny Vallet, Nicola Ballhausen, Nathalie Mella, Marie Baeriswyl, Julia Sauter, Michel Oris, Jürgen Maurer, Matthias Kliegel. Cross-lagged relation of leisure activity participation to Trail Making Test performance 6 years later: Differential patterns in old age and very old age. Neuropsychology. 2019; 33 (2):234-244.

Chicago/Turabian Style

Andreas Ihle; Delphine Fagot; Fanny Vallet; Nicola Ballhausen; Nathalie Mella; Marie Baeriswyl; Julia Sauter; Michel Oris; Jürgen Maurer; Matthias Kliegel. 2019. "Cross-lagged relation of leisure activity participation to Trail Making Test performance 6 years later: Differential patterns in old age and very old age." Neuropsychology 33, no. 2: 234-244.

Original articles
Published: 01 January 2019 in Revista Brasileira de Geriatria e Gerontologia
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Objectives: To study the reliability/stability of the Cognitive Telephone Screening Instrument (COGTEL) for the assessment of cognitive functions, and to investigate the concurrent validity (that is, the relationship between the COGTEL scores and external variables, such as level of education and MMSE results) in a pilot study of elderly persons residing in the community in the municipal regions of Apuí, Fonte Boa and Manaus (Amazonas, Brazil). Method: This pilot study included 90 elderly persons (29 men and 61 women) aged 60-85 years of age [68.2 (± 6.7)]. The COGTEL, the MMSE and socio-economic survey were applied in the form of two interviews, a week apart and under the same conditions. Results: The test-retest intraclass correlation coefficient of the COGTEL total score (and respective six subtests), MMSE and educational level ranged from acceptable to high (0.708 < R

ACS Style

Maria Antonieta Tinôco; Élvio Rúbio Gouveia; Andreas Ihle; Adilson Marques; Bruna R. Gouveia; Matthias Kliegel. The Cognitive Telephone Screening Instrument (COGTEL): a reliable and valid tool for the assessment of cognitive functioning in the Brazilian elderly. Revista Brasileira de Geriatria e Gerontologia 2019, 22, 1 .

AMA Style

Maria Antonieta Tinôco, Élvio Rúbio Gouveia, Andreas Ihle, Adilson Marques, Bruna R. Gouveia, Matthias Kliegel. The Cognitive Telephone Screening Instrument (COGTEL): a reliable and valid tool for the assessment of cognitive functioning in the Brazilian elderly. Revista Brasileira de Geriatria e Gerontologia. 2019; 22 (1):1.

Chicago/Turabian Style

Maria Antonieta Tinôco; Élvio Rúbio Gouveia; Andreas Ihle; Adilson Marques; Bruna R. Gouveia; Matthias Kliegel. 2019. "The Cognitive Telephone Screening Instrument (COGTEL): a reliable and valid tool for the assessment of cognitive functioning in the Brazilian elderly." Revista Brasileira de Geriatria e Gerontologia 22, no. 1: 1.

Articles
Published: 31 December 2018 in Aging & Mental Health
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Objective: The adverse effects of anxiety on cognition are widely recognized. According to Attentional Control Theory, worry (i.e. facet of cognitive anxiety) is the component that is responsible for these effects, and working memory capacity (WMC) plays an important role in regulating them. Despite the increasing importance of this problem with aging, little is known about how these mechanisms interact in old age. In this study, we explored the distinct contributions of the somatic and cognitive components of anxiety to neuropsychological performance, and the potential moderating role of WMC. Method: We administered cognitive tasks testing processing speed, cognitive flexibility and working memory to 605 older adults, who also underwent depression and test anxiety assessments (data from VLV study). Results: Multiple regression analyses showed that cognitive (but not somatic) aspects of anxiety affected cognitive flexibility. The effect of cognitive anxiety on processing speed was moderated by WMC: the anxiety-performance association was lower for participants with greater WMC. Conclusion: Results confirmed the specific role of worry in the anxiety–performance relationship in old age and supported the hypothesis that working memory resources regulates its deleterious effect on cognition. The absence of a moderation effect in the more costly switching task may reflect a limitation of resources with aging.

ACS Style

Nathalie Mella; Fanny Vallet; Marine Beaudoin; Delphine Fagot; Marie Baeriswyl; Nicola Ballhausen; Grégoire Métral; Julia Sauter; Andreas Ihle; Rainer Gabriel; Michel Oris; Matthias Kliegel; Olivier Desrichard. Distinct effects of cognitive versus somatic anxiety on cognitive performance in old age: the role of working memory capacity. Aging & Mental Health 2018, 24, 604 -610.

AMA Style

Nathalie Mella, Fanny Vallet, Marine Beaudoin, Delphine Fagot, Marie Baeriswyl, Nicola Ballhausen, Grégoire Métral, Julia Sauter, Andreas Ihle, Rainer Gabriel, Michel Oris, Matthias Kliegel, Olivier Desrichard. Distinct effects of cognitive versus somatic anxiety on cognitive performance in old age: the role of working memory capacity. Aging & Mental Health. 2018; 24 (4):604-610.

Chicago/Turabian Style

Nathalie Mella; Fanny Vallet; Marine Beaudoin; Delphine Fagot; Marie Baeriswyl; Nicola Ballhausen; Grégoire Métral; Julia Sauter; Andreas Ihle; Rainer Gabriel; Michel Oris; Matthias Kliegel; Olivier Desrichard. 2018. "Distinct effects of cognitive versus somatic anxiety on cognitive performance in old age: the role of working memory capacity." Aging & Mental Health 24, no. 4: 604-610.