Magdi Osman

Prof. Magdi Osman

Department of Food & Nutritional sciences, King Saud University, Riyadh, Ar Riyāḑ, Saudi Arabia

Research Focus & Metrics

Academic Career Length

23Years (2004-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2004 in Plant Foods for Human Nutrition
Verified
Journal Article
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MOMagdi Osman
Magdi Osman

31 October 2022 in Agriculture
Verified
Journal Article
Open access
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EMEman A. Mohammed
Eman A. Mohammed
IAIsmat G. Abdalla
Ismat G. Abdalla
MAMohammed Alfawaz
Mohammed Alfawaz
MAMohammed Ahmed
Mohammed Ahmed
SASalah Almaiman
Salah Almaiman
AHAmro Hassan
Amro Hassan
The present study aimed to investigate the total phenolics, total flavonoids, and antioxidant activity in terms of the DPPH scavenging, reducing power, and H2O2 scavenging of the aerial parts of onion, white radish, red radish, carrot, and beet as affected by different extraction solvents. Generally, the aerial part of these vegetables has high antioxidant properties. Samples were extracted with methanol (100 and 70%), ethanol (100 and 70%), and water. Total phenolic content was highest when the samples were extracted using 100% methanol, while extraction with 100% ethanol yielded the highest total flavonoids. The highest DPPH activity and H2O2 scavenging values were obtained by extraction of the aerial plant parts with 70% ethanol, and the 70% methanol extract had the highest reducing power. Partial least regression (PLS) was performed to validate the optimum solvent for extraction of the antioxidants and their activity in each plant. The PLS indicated that there was a variation in the validation of the different extracts for each plant. The high antioxidant capacity of root vegetables, which is natural, indicates that they may have health and dietetic advantages for consumers.

1 June 2021 in Saudi Journal of Biological Sciences
Verified
Journal Article
Open access
DADalal A. Alkhudhayri
Dalal A. Alkhudhayri
MOMagdi Osman
Magdi Osman
GAGhedeir Alshammari
Ghedeir Alshammari
SMSalah A. Al Maiman
Salah A. Al Maiman
MYMohammed Abdo Yahya
Mohammed Abdo Yahya
This present research investigated the anti-obesity and hepatoprotective effects of ethanolic Moringa peregrina leaf (MPLE) and bark extracts (MPBE), in the rats fed with a high-fat diet (HFD). Healthy male rats (n = 48) were randomly distributed to six groups (n = 8): control AIN-93 diet; HFD; HFD + MPBE bark extracts ((300 mg/kg); HFD + MPBE (600 mg/kg); HFD + MPLE (300 mg/kg); HFD + MPLE (600 mg/kg). HFD-fed rats in the Moringa peregrina (MP) treatment groups received orally administered MP leaf or bark extract daily for eight weeks. The results revealed that both doses of MP leaf extract significantly reduced HFD-induced increases in their food intake and the gained body weight, fat pad weights (visceral, subcutaneous, and epididymal), glucose and insulin plasma levels, and leptin and resistin serum levels in HFD-fed rats. Concomitantly, MP leaf extract improved glucose levels after oral or intraperitoneal glucose tolerance tests, reduced serum cholesterol, triglycerides, and the low-density lipoprotein LDL concentration, reduced hepatic triglycerides and cholesterol levels, and increased serum high-density lipoproteins HDL levels and triglycerides and cholesterol levels in fecal. Moreover, the administration of MPLE to HFD-fed rats improved liver architecture, reduced fat accumulation, reduced hepatic malondialdehyde, tumor necrosis factor-α, and interleukin-6 levels. Hepatic glutathione peroxidase, superoxide dismutase, and catalase activities were significantly increased. All observed effects were more pronounced in HFD-fed rats treated with a 600 mg/kg MP dose. However, neither dose of MPBE altered the measured markers in the HFD-fed rats. In conclusion, MPLE showed potential anti-obesity and hepatoprotective activity in HFD-induced obese rats, mediated by reduced lipid absorption, anti-hyperlipidemic effects, and hepatic antioxidant effects.

14 April 2017 in Lipids in Health and Disease
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Journal Article
Open access
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AAAbdullah S. Alghamdi
Abdullah S. Alghamdi
MYMohammed Abdo Yahya
Mohammed Abdo Yahya
GAGhedeir Alshammari
Ghedeir Alshammari
MOMagdi Osman
Magdi Osman
Despite the prevalence of overweight and obesity and increases in associated diseases such as diabetes and heart disease in the Saudi population, no studies have addressed the spread of obesity among Saudi police officers. Therefore, the present study aimed to assess the prevalence of overweight and obesity and associations with biochemical parameters among the police in Riyadh. The study involved a cross-sectional survey of 160 police officers in Riyadh, Saudi Arabia. Anthropometric measurements, blood pressure, lipid profiles and fasting blood sugar levels were measured for all individuals. According to the results, the average body mass index (BMI) was 27.5 ± 5.1, indicating an increase in overweight in this population and 66.9% were overweight or obese. Moreover, the mean systolic and diastolic blood pressure values were 119.5 and 79.4 mmHg, respectively, within normal limits. The mean total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), and triglyceride (TG) levels were 187.5, 43.9, 119.5 and 124.5 mg/100 ml, respectively. These BMI and biochemical findings suggest a high proportion of overweight and obese individuals in the sample population, as well as an increase in the proportion of individuals with high levels of biochemical indicators who are therefore susceptible to heart disease and diabetes. The study recommends using preventive programs to combat obesity and overweight and related diseases and conducting further studies using measures other than BMI.

26 May 2019 in Journal of Food Biochemistry
Verified
Journal Article
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MAMohamed M. M. Alqarni
Mohamed M. M. Alqarni
MOMagdi Osman
Magdi Osman
DADalia S. Al‐Tamimi
Dalia S. Al‐Tamimi
MGMustafa A. Gassem
Mustafa A. Gassem
AAAbdulrahman S. Al‐Khalifa
Abdulrahman S. Al‐Khalifa
IAIsam Ahmed
Isam Ahmed
This study investigated the chemical composition, in vivo antioxidant, and antihyperlipidemic potential of Ajwa date polyphenol extract (DPE). Chemical analysis revealed that the Ajwa dates contain substantial amounts of carbohydrates, energy, potassium, iron, polyphenols, and flavonoids. In vivo studies showed that feeding rats with cholesterol-rich diets significantly (p ≤ 0.05) increased their body and liver weights, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C), and triglycerides (TG) in plasma and liver, and reduced the high-density lipoprotein cholesterol (HDL-C) content and antioxidant enzyme activities. However, oral administration of 25, 50, and 100 mg DPE/kg body weight to hypercholestrolemic rats, significantly (p ≤ 0.05) reduced their body and liver weights, total hepatic cholesterol, LDL-C, VLDL-C, and triglycerides. Furthermore, treatment with DPE improved (p ≤ 0.05) the HDL-C concentration and antioxidant enzyme activity in a concentration-dependent fashion, thereby regulating lipid profiles, enhancing the antioxidant defense system. Overall, DPE showed significant (p ≤ 0.05) nutritional, antioxidants, and antihyperlipidemic benefits. Practical applications Coronary heart disease is the leading cause of death in the world. Consumption of fruits and vegetables rich in polyphenol have shown to exert cardio-protective effect. This work revealed that phenolic extracts of Ajwa dates have positive impacts on the health as it reduced TC, LDL-C, and lipids VLDL-C and improved HDL-C and the antioxidant defense system in rats. The findings of this study could aid in the profound understanding of the nutritional and health potentials of Ajwa dates and thus could help in utilization of these valuable fruits for the prevention and curing of cardiovascular diseases.

30 March 2021 in Foods
Verified
Journal Article
Open access
PDF file
SASalah Almaiman
Salah Almaiman
NANawal Albader
Nawal Albader
IAIbrahim Almusallam
Ibrahim Almusallam
MAMohammed Jawad Al-Saád
Mohammed Jawad Al-Saád
SASarah Alsuliam
Sarah Alsuliam
AHAmro Hassan
Amro Hassan
This study investigated the effect of solar drying on storability and physiochemical and antioxidant capacities of dried tomatoes. Sliced fruit was dried at 45 ± 2 °C for 24 h under a solar tunnel dryer and stored at ambient temperature for 90 and 180 days. Solar drying treatments significantly (p < 0.05) reduced the bacterial and mold load, and eliminated Staphylococcus aureus, S. saprophyticus, and Escherichia coli in all samples. Solar drying treatment reduced the water activity of the dried tomato’s to 0.31 that remained at the same level during storage period 180 days. Storage of dried tomato slices resulted in the decrease of both color and vitamin C content while it increased the total carotenoid, lycopene, phenolic compound content, and antioxidant activity. Furthermore, the principle component analysis (PCA) revealed that solar drying of tomato slices enhanced its physicochemical properties, antioxidant capacity particularly after storage for 90 and 180 days. Interestingly, the solar drying process enhanced tomato slices storage and physicochemical characteristics, that resulted in extending the shelf life by up to 6 months, indicating the great potential application of low-tech solar in food industry and could become an emerging effective post-harvest preservative method for seasonal perishable vegetable and fruit, particularly in developing countries.