The Water-Cooled Lead–Lithium Breeding Blanket (WCLL BB) is one of the two blanket concept candidates to become the driver blanket of the EU-DEMO reactor. The design was enacted with a holistic approach. The influence that neutronics, thermal-hydraulics (TH), thermo-mechanics (TM) and magneto-hydro-dynamics (MHD) may have on the design were considered at the same time. This new approach allowed for the design team to create a WCLL BB layout that is able to comply with different foreseen requirements in terms of integration, tritium self-sufficiency, and TH and TM needs. In this paper, the rationale behind the design choices and the main characteristics of the WCLL BB needed for the EU-DEMO are reported and discussed. Finally, the main achievements reached during the pre-conceptual design phase and some remaining open issues to be further investigated in the upcoming conceptual design phase are reported as well.