All life forms on earth, including humans, are constantly subjected to the universal force of gravitation, and thus to forces from within and surrounding the body. Through the study of the interaction of these forces and their effects, the form, function and motion of our bodies can be examined and the resulting knowledge applied to promote quality of life. Under gravity and other loads, and controlled by the nervous system, human movement is achieved through a complex and highly coordinated mechanical interaction between bones, muscles, ligaments and joints within the musculoskeletal system. Any injury to, or lesion in, any of the individual elements of the musculoskeletal system will change the mechanical interaction and cause degradation, instability or disability of movement. On the other hand, proper modification, manipulation and control of the mechanical environment can help prevent injury, correct abnormality, and speed healing and rehabilitation. Therefore, understanding the biomechanics and loading of each element during movement using motion analysis is helpful for studying disease etiology, making decisions about treatment, and evaluating treatment effects. In this article, the history and methodology of human movement biomechanics, and the theoretical and experimental methods developed for the study of human movement, are reviewed. Examples of motion analysis of various patient groups, prostheses and orthoses, and sports and exercises, are used to demonstrate the use of biomechanical and stereophotogrammetry‐based human motion analysis studies to address clinical issues. It is suggested that further study of the biomechanics of human movement and its clinical applications will benefit from the integration of existing engineering techniques and the continuing development of new technology.

Measurement of the changes of the three-dimensional (3D) motion and surface kinematics of the knee under different external loading conditions is essential for the understanding and evaluation of the function of the joint, as well as for relevant clinical applications. Knee extension exercise (KEE) has been applied extensively in the rehabilitation programs of patients with various knee disorders. This study measured the 3D knee kinematics of eight normal subjects during active knee extension for unloaded and loaded conditions using a voxel-based method for the registration of fluoroscopic images with CT bone data. The knee kinematics during unloaded conditions were found to be similar to previous findings. A mass of 5 kg at the ankle did not affect the joint angles but significantly altered the lateral contact positions during knee extension, especially at knee flexion angles higher than 75 degrees, and also reduced the asymmetry of the surface kinematics between the medial and lateral condyles. The results of the current study may be useful for knee replacement design and for developing guidelines for the use of KEEs for the rehabilitation of patients with knee disorders.

To determine the joint loading during elliptical exercise (EE) by a detailed three-dimensional dynamic analysis, and to compare the results with those during level walking. Fifteen male adults performed level walking and EE while 3D kinematic data, right pedal reaction forces (PRF), and ground reaction forces (GRF) were measured. Pedal rate (cadence) and step length during EE without workload were set according to those measured during level walking for each subject. The motion of the body's center of mass, lower-limb-joint angles and moments were obtained. Pedal rates and step lengths were 52.20 rpm (SD=2.34) and 50.56 cm (SD=2.14), respectively. During early stance the vertical PRF was smaller than the GRF, and the medial and posterior shear components were greater. PRF also occurred during swing. Loading rates around heelstrike during EE were all smaller than those during walking. During EE, the peak flexion angles of the hip, knee and ankle were greater. Peak hip flexor and knee extensor moments were also greater, whereas peak ankle plantarflexor moments and all abductor moments were smaller. Different lower-limb kinematics and kinetics were found between EE and level walking. Smaller vertical PRF and loading rates during EE were achieved at the expense of greater hip flexor and knee extensor moments. Use of the elliptical trainer for athletic and rehabilitative training would have to consider users' joint function and muscle strength, especially at the knee, to avoid injuries.