Much of the economic burden in melanoma screening results from biopsies and excisions of benign lesions, especially in patients with multiple melanocytic nevi. The clinical morphologic criteria summarized by the ABCD rule (asymmetry, border irregularity, color variegation, and diameter >6 mm) are not useful in assessing nevi in these patients because many of their benignlesions have positive ABCD features. Dermoscopy has been shown to reduce the number of unnecessary excisions in melanoma screening^1,2; however, irregular dermoscopic features are noted in numerous lesions among patients with multiple nevi, and unnecessary biopsies and excisions are still performed. More reliable screening strategies are needed to improve melanoma screening performance in this patient population.

Eccrine poroma can mimic benign and malignant melanocytic and non-melanocytic lesions. To date, little is known about the dermoscopic features of this condition. Seven histopathologically proven cases of eccrine poroma were examined using dermoscopy by three independent dermatologists. Both glomerular and hairpin vessels were observed in 71% of cases, whereas linear irregular vessels were observed in 43% of cases. A white-to-pink halo surrounding the vessels and multiple pink-white structureless areas were also frequently found (in 86% and 71% of cases, respectively). Three dermoscopic "profiles were identified all characterized by the presence of halo surrounding the vessels as well as by the association of two additional different features namely: glomerular vessels and pink-white structureless areas glomerular and linear irregular vessels hairpin vessels and linear irregular vessels. However due to the small number of lesions studied so far we suggest that these profiles should be considered as likely but not definitely pathognomonic signs of eccrine poroma.

Background: The dermoscopic patterns of pigmented skin tumors are influenced by the body site. Objective: To evaluate the clinical and dermoscopic features associated with pigmented vulvar lesions. Methods: Retrospective analysis of clinical and dermoscopic images of vulvar lesions. The χ² test was used to test the association between clinical data and histopathological diagnosis. Results: A total of 42 (32.8%) melanocytic and 86 (67.2%) nonmelanocytic vulvar lesions were analyzed. Nevi significantly prevailed in younger women compared with melanomas and melanosis and exhibited most commonly a globular/cobblestone (51.3%) and a mixed (21.6%) pattern. Dermoscopically all melanomas showed a multicomponent pattern. Melanotic macules showed clinical overlapping features with melanoma, but their dermoscopic patterns differed significantly from those observed in melanomas. Conclusion: The diagnosis and management of pigmented vulvar lesions should be based on a good clinicodermoscopic correlation. Dermoscopy may be helpful in the differentiation of solitary melanotic macules from early melanoma.