In this work, we present methods for the personalization of a system for the continuous estimation of pain intensity from bio-physiological channels. We investigate various ways to estimate the similarity of persons and to retrieve the most informative ones using meta-information, personality traits, and machine learning techniques. Given this information, specialized classifiers can be created that are both, more efficient in terms of complexity and training times and also more accurate than classifiers trained on the complete data. To capture the most information in the different bio-physiological channels, we cover a broad spectrum of different feature extraction algorithms. Furthermore, we show that the system is capable of running in real-time and discuss issues that arise when dealing with incremental data processing. In extensive experiments we verify the validity of our approach.

In this paper, a modified adaptive K-means (MAKM) method is proposed to extract the region of interest (ROI) from the local and public datasets. The local image datasets are collected from Bethezata General Hospital (BGH) and the public datasets are from Mammographic Image Analysis Society (MIAS). The same image number is used for both datasets, 112 are abnormal and 208 are normal. Two texture features (GLCM and Gabor) from ROIs and one CNN based extracted features are considered in the experiment. CNN features are extracted using Inception-V3 pre-trained model after simple preprocessing and cropping. The quality of the features are evaluated individually and by fusing features to one another and five classifiers (SVM, KNN, MLP, RF, and NB) are used to measure the descriptive power of the features using cross-validation. The proposed approach was first evaluated on the local dataset and then applied to the public dataset. The results of the classifiers are measured using accuracy, sensitivity, specificity, kappa, computation time and AUC. The experimental analysis made using GLCM features from the two datasets indicates that GLCM features from BGH dataset outperformed that of MIAS dataset in all five classifiers. However, Gabor features from the two datasets scored the best result with two classifiers (SVM and MLP). For BGH and MIAS, SVM scored an accuracy of 99%, 97.46%, the sensitivity of 99.48%, 96.26% and specificity of 98.16%, 100% respectively. And MLP achieved an accuracy of 97%, 87.64%, the sensitivity of 97.40%, 96.65% and specificity of 96.26%, 75.73% respectively. Relatively maximum performance is achieved for feature fusion between Gabor and CNN based extracted features using MLP classifier. However, KNN, MLP, RF, and NB classifiers achieved almost 100% performance for GLCM texture features and SVM scored an accuracy of 96.88%, the sensitivity of 97.14% and specificity of 96.36%. As compared to other classifiers, NB has scored the least computation time in all experiments.