Alexander R. A. Anderson, PhD is chair of the Integrated Mathematical Oncology (IMO) Department at Moffitt Cancer Center. Most of his early cancer work at Dundee university was on developing mathematical models of tumor progression and treatment, including anti-angiogenesis, radiotherapy, tumor invasion, intra-tumor heterogeneity evolution. Due to his belief in mathematical models in cancer research he moved to Moffitt in 2008 to establish the IMO. At Moffitt his research shifted to developing organ specific models of tumor initiation and progression, examine the key role of the microenvironment as a selective force in cancer evolution. Recently, clinical translation has become central to his research leading to the development of eco-evolutionary therapies that seek to control cancer rather than eradicate it.