A technique for synthesizing biocompatible hydrogels by cross-linking calcium-form poly(γ-glutamic acid), alginate sodium, and Pluronic F-127 was created, in which alginate can be cross-linked by Ca²⁺from Ca–γ-PGA directly andγ-PGA molecules introduced into the alginate matrix to provide pH sensitivity and hemostasis. Mechanical properties, swelling behavior, and blood compatibility were investigated for each hydrogel compared with alginate and forγ-PGA hydrogel with the sodium form only. Adding F-127 improves mechanical properties efficiently and influences the temperature-sensitive swelling of the hydrogels but also has a minor effect on pH-sensitive swelling and promotes anticoagulation. MG-63 cells were used to test biocompatibility. Gelation occurred gradually through change in the elastic modulus as the release of calcium ions increased over time and caused ionic cross-linking, which promotes the elasticity of gel. In addition, the growth of MG-63 cells in the gel reflected nontoxicity. These results showed that this biocompatible scaffold has potential for application in bone materials.

Imbalance crosslink density and polymer concentration gradient is formed within the traditional alginate hydrogel using calcium chloride as a crosslinking agent in external gelation for instantaneously process. In this studying, type I collagen (Col

Thin-wall injection molding parts have the shrinkage distortion problem, this is mainly caused by the setting of processing parameters. Gray relational analysis and Taguchi method were applied to obtain the combination of processing parameters that could produce the product with optimal multiple quality characteristics. We used gray relational analysis to solve the single quality characteristic problem of Taguchi method and used the response graph of gray relational analysis to receive the optimal processing parameters combinations, which would produce the product with multiple quality characteristics. Finally, the confirmation experiment proved the reliability and reproducibility of this experiment with 95% confidence interval.