Alfredo Illanes

Prof. Alfredo Illanes

Faculty of Medicine, SURAG, Otto-von-Guericke-University, Magdeburg, Germany

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 August 2021 in Sensors
Verified
Journal Article
Open access
PDF file
Andrew A. GumbsAndrew A. Gumbs
Andrew A. Gumbs
IFIsabella Frigerio
Isabella Frigerio
Gaya SpolveratoGaya Spolverato
Gaya Spolverato
Roland S. CronerRoland S. Croner
Roland S. Croner
AIAlfredo Illanes
Alfredo Illanes
Eyad ElyanEyad Elyan
Eyad Elyan
Most surgeons are skeptical as to the feasibility of autonomous actions in surgery. Interestingly, many examples of autonomous actions already exist and have been around for years. Since the beginning of this millennium, the field of artificial intelligence (AI) has grown exponentially with the development of machine learning (ML), deep learning (DL), computer vision (CV) and natural language processing (NLP). All of these facets of AI will be fundamental to the development of more autonomous actions in surgery, unfortunately, only a limited number of surgeons have or seek expertise in this rapidly evolving field. As opposed to AI in medicine, AI surgery (AIS) involves autonomous movements. Fortuitously, as the field of robotics in surgery has improved, more surgeons are becoming interested in technology and the potential of autonomous actions in procedures such as interventional radiology, endoscopy and surgery. The lack of haptics, or the sensation of touch, has hindered the wider adoption of robotics by many surgeons; however, now that the true potential of robotics can be comprehended, the embracing of AI by the surgical community is more important than ever before. Although current complete surgical systems are mainly only examples of tele-manipulation, for surgeons to get to more autonomously functioning robots, haptics is perhaps not the most important aspect. If the goal is for robots to ultimately become more and more independent, perhaps research should not focus on the concept of haptics as it is perceived by humans, and the focus should be on haptics as it is perceived by robots/computers. This article will discuss aspects of ML, DL, CV and NLP as they pertain to the modern practice of surgery, with a focus on current AI issues and advances that will enable us to get to more autonomous actions in surgery. Ultimately, there may be a paradigm shift that needs to occur in the surgical community as more surgeons with expertise in AI may be needed to fully unlock the potential of AIS in a safe, efficacious and timely manner.

18 May 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
ABAxel Boese
Axel Boese
CWCora Wex
Cora Wex
Roland S. CronerRoland S. Croner
Roland S. Croner
ULUwe Bernd Liehr
Uwe Bernd Liehr
JWJohann Jakob Wendler
Johann Jakob Wendler
AIAlfredo Illanes
Alfredo Illanes
One of the most applied imaging methods in medicine is endoscopy. A highly specialized image modality has been developed since the first modern endoscope, the “Lichtleiter” of Bozzini was introduced in the early 19th century. Multiple medical disciplines use endoscopy for diagnostics or to visualize and support therapeutic procedures. Therefore, the shapes, functionalities, handling concepts, and the integrated and surrounding technology of endoscopic systems were adapted to meet these dedicated medical application requirements. This survey gives an overview of modern endoscopic technology’s state of the art. Therefore, the portfolio of several manufacturers with commercially available products on the market was screened and summarized. Additionally, some trends for upcoming developments were collected.

29 June 2022 in Sensors
Verified
Journal Article
Open access
PDF file
Andrew A. GumbsAndrew A. Gumbs
Andrew A. Gumbs
VGVincent Grasso
Vincent Grasso
NBNicolas Bourdel
Nicolas Bourdel
Roland S. CronerRoland S. Croner
Roland S. Croner
Gaya SpolveratoGaya Spolverato
Gaya Spolverato
Eyad ElyanEyad Elyan
Eyad Elyan
This is a review focused on advances and current limitations of computer vision (CV) and how CV can help us obtain to more autonomous actions in surgery. It is a follow-up article to one that we previously published in Sensors entitled, “Artificial Intelligence Surgery: How Do We Get to Autonomous Actions in Surgery?” As opposed to that article that also discussed issues of machine learning, deep learning and natural language processing, this review will delve deeper into the field of CV. Additionally, non-visual forms of data that can aid computerized robots in the performance of more autonomous actions, such as instrument priors and audio haptics, will also be highlighted. Furthermore, the current existential crisis for surgeons, endoscopists and interventional radiologists regarding more autonomy during procedures will be discussed. In summary, this paper will discuss how to harness the power of CV to keep doctors who do interventions in the loop.

23 September 2018 in Journal of Healthcare Engineering
Verified
Journal Article
Open access
PDF file
PPPrabal Poudel
Prabal Poudel
AIAlfredo Illanes
Alfredo Illanes
DSDebdoot Sheet
Debdoot Sheet
MFMichael Friebe
Michael Friebe
The thyroid is one of the largest endocrine glands in the human body, which is involved in several body mechanisms like controlling protein synthesis and the body's sensitivity to other hormones and use of energy sources. Hence, it is of prime importance to track the shape and size of thyroid over time in order to evaluate its state. Thyroid segmentation and volume computation are important tools that can be used for thyroid state tracking assessment. Most of the proposed approaches are not automatic and require long time to correctly segment the thyroid. In this work, we compare three different nonautomatic segmentation algorithms (i.e., active contours without edges, graph cut, and pixel-based classifier) in freehand three-dimensional ultrasound imaging in terms of accuracy, robustness, ease of use, level of human interaction required, and computation time. We figured out that these methods lack automation and machine intelligence and are not highly accurate. Hence, we implemented two machine learning approaches (i.e., random forest and convolutional neural network) to improve the accuracy of segmentation as well as provide automation. This comparative study intends to discuss and analyse the advantages and disadvantages of different algorithms. In the last step, the volume of the thyroid is computed using the segmentation results, and the performance analysis of all the algorithms is carried out by comparing the segmentation results with the ground truth.

13 August 2018 in Scientific Reports
Verified
Journal Article
Open access
PDF file
AIAlfredo Illanes
Alfredo Illanes
ABAxel Boese
Axel Boese
IMIván Maldonado
Iván Maldonado
APAli Pashazadeh
Ali Pashazadeh
ASAnna Schaufler
Anna Schaufler
Michael FriebeMichael Friebe
Michael Friebe
We propose a new and complementary approach to image guidance for monitoring medical interventional devices (MID) with human tissue interaction and surgery augmentation by acquiring acoustic emission data from the proximal end of the MID outside the patient to extract dynamical characteristics of the interaction between the distal tip and the tissue touched or penetrated by the MID. We conducted phantom based experiments (n = 955) to show dynamic tool/tissue interaction during tissue needle passage (a) and vessel perforation caused by guide wire artery perforation (b). We use time-varying auto-regressive (TV-AR) modelling to characterize the dynamic changes and time-varying maximal energy pole (TV-MEP) to compute subsequent analysis of MID/tissue interaction characterization patterns. Qualitative and quantitative analysis showed that the TV-AR spectrum and the TV-MEP indicated the time instants of the needle path through different phantom objects (a) and clearly showed a perforation versus other generated artefacts (b). We demonstrated that audio signals acquired from the proximal part of an MID could provide valuable additional information to surgeons during minimally invasive procedures.

27 October 2020 in Sensors
Verified
Journal Article
Open access
PDF file
Elmer Gomes AtaideElmer Gomes Ataide
Elmer Gomes Ataide
NPNikhila Ponugoti
Nikhila Ponugoti
AIAlfredo Illanes
Alfredo Illanes
SSSimone Agnes Schenke
Simone Agnes Schenke
Michael Christoph KreisslMichael Christoph Kreissl
Michael Christoph Kreissl
Michael FriebeMichael Friebe
Michael Friebe
The classification of thyroid nodules using ultrasound (US) imaging is done using the Thyroid Imaging Reporting and Data System (TIRADS) guidelines that classify nodules based on visual and textural characteristics. These are composition, shape, size, echogenicity, calcifications, margins, and vascularity. This work aims to reduce subjectivity in the current diagnostic process by using geometric and morphological (G-M) features that represent the visual characteristics of thyroid nodules to provide physicians with decision support. A total of 27 G-M features were extracted from images obtained from an open-access US thyroid nodule image database. 11 significant features in accordance with TIRADS were selected from this global feature set. Each feature was labeled (0 = benign and 1 = malignant) and the performance of the selected features was evaluated using machine learning (ML). G-M features together with ML resulted in the classification of thyroid nodules with a high accuracy, sensitivity and specificity. The results obtained here were compared against state-of the-art methods and perform significantly well in comparison. Furthermore, this method can act as a computer aided diagnostic (CAD) system for physicians by providing them with a validation of the TIRADS visual characteristics used for the classification of thyroid nodules in US images.