Butanol is an alternative type of fuel. Amid the depletion of the world’s (accessible) petroleum reserves, butanol is considered to be a potential energy source. Although butanol production was...

This review presents the main directions and experimental data aimed at searching for active producers of lipids among different species of microorganisms

The inhibition of a bacterial cell division protein, filamentous temperature-sensitive Z (FtsZ), prevents the reproduction of Mycobacteria. To propose potent inhibitors of FtsZ, the binding properties of FtsZ with various derivatives of Zantrin ZZ3 were investigated at an electronic level, using molecular simulations. We here employed protein–ligand docking, classical molecular mechanics (MM) optimizations, and ab initio fragment molecular orbital (FMO) calculations. Based on the specific interactions between FtsZ and the derivatives, as determined by FMO calculations, we proposed novel ligands, which can strongly bind to FtsZ and inhibit its aggregations. The introduction of a hydroxyl group into ZZ3 was found to enhance its binding affinity to FtsZ.

The aim of this work was to study phylogenetic relationships between the new producer strain Bacillus subtilis IFBG MK-2 and the existing strains and incre