Jhonatan Gonzalez-Santamaria

Dr. Jhonatan Gonzalez-Santamaria

Fundación Universitaria del Area Andina, Pereira, Risaralda, Colombia
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Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 January 2022 in Sports
Verified
Journal Article
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MMMateo Baena Marín
Mateo Baena Marín
Andrés Rojas JaramilloAndrés Rojas Jaramillo
Andrés Rojas Jaramillo
Jhonatan Gonzalez-SantamariaJhonatan Gonzalez-Santamaria
Jhonatan Gonzalez-Santamaria
David Rodríguez-RosellDavid Rodríguez-Rosell
David Rodríguez-Rosell
Jorge Luis PetroJorge Luis Petro
Jorge Luis Petro
Diego A. BonillaDiego A. Bonilla
Diego A. Bonilla
Weight resistance training (RT) has been shown to positively influence physical performance. Within the last two decades, a methodology based on monitoring RT through movement velocity (also called velocity-based resistance training, VBRT) has emerged. The aim of this PRISMA-based systematic review was to evaluate the effect of VBRT programs on variables related to muscle strength (one-repetition maximum, 1-RM), and high-speed actions (vertical jump, and sprint performance) in trained subjects. The search for published articles was performed in PubMed/MEDLINE, SPORT Discus/EBSCO, OVID, Web of Science, Scopus, and EMBASE databases using Boolean algorithms independently. A total of 22 studies met the inclusion criteria of this systematic review (a low-to-moderate overall risk of bias of the analyzed studies was detected). VBRT is an effective method to improve 1-RM, vertical jump and sprint. According to the results of the analyzed studies, it is not necessary to reach high muscle failure in order to achieve the best training results. These findings reinforce the fact that it is possible to optimize exercise adaptations with less fatigue. Future studies should corroborate these findings in female population.

4 August 2023 in Pharmaceuticals
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JMJosé Antonio Mora-melgem
José Antonio Mora-melgem
Jesús Gilberto Arámburo-GálvezJesús Gilberto Arámburo-Gálvez
Jesús Gilberto Arámburo-Gálvez
FCFeliznando Isidro Cárdenas-Torres
Feliznando Isidro Cárdenas-Torres
Jhonatan Gonzalez-SantamariaJhonatan Gonzalez-Santamaria
Jhonatan Gonzalez-Santamaria
GRGiovanni Ramírez
Giovanni Ramírez
NONoé Ontiveros
Noé Ontiveros
Chickpea (Cicer arietinum L.) peptides can inhibit dipeptidyl peptidase IV (DPP-IV), an important type 2 diabetes mellitus therapeutic target. The molecular interactions between the inhibitory peptides and the active site of DPP-IV have not been thoroughly examined, nor have their pharmacokinetic properties. Therefore, the predictions of legumin- and provicilin-derived DPP-IV inhibitory peptides, their molecular interactions with the active site of DPP-IV, and their pharmacokinetic properties were carried out. Ninety-two unique DPP-IV inhibitory peptides were identified. Papain and trypsin were the enzymes with the highest AE (0.0927) and lowest BE (6.8625 × 10−7) values, respectively. Peptide binding energy values ranged from −5.2 to −7.9 kcal/mol. HIS-PHE was the most potent DPP-IV inhibitory peptide and interacts with residues of the active sites S1 (TYR662) and S2 (GLU205/ARG125 (hydrogen bonds: <3.0 Å)), S2 (GLU205/GLU206 (electrostatic interactions: <3.0 Å)), and S2′ pocket (PHE357 (hydrophobic interaction: 4.36 Å)). Most peptides showed optimal absorption (76.09%), bioavailability (89.13%), and were non-toxic (97.8%) stable for gastrointestinal digestion (73.9%). Some peptides (60.86%) could also inhibit ACE-I. Chickpea is a source of non-toxic and bioavailable DPP-IV-inhibitory peptides with dual bioactivity. Studies addressing the potential of chickpea peptides as therapeutic or adjunct agents for treating type 2 diabetes are warranted.

1 January 2018 in Nutrición Hospitalaria
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Journal Article
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DRDavid Rincon-pabon
David Rincon-pabon
YUYeraldin Urazán-Hernández
Yeraldin Urazán-Hernández
Jhonatan Gonzalez-SantamariaJhonatan Gonzalez-Santamaria
Jhonatan Gonzalez-Santamaria
Objective: iron deficiency anemia is associated with adverse results for health and it is highly prevalent worldwide. The current study evaluated the prevalence and the sociodemographic factors associated with iron deficiency anemia in a sample of Colombian pregnant women. Materials and methods: the secondary analysis for the obtained information at the National Nutrition Survey (ENSIN) 2010 of Colombia in a probabilistic sample of 1,385 pregnant women between 13 and 49 years old. Hemoglobin concentration, ferritin plasmatic levels, sociodemographic levels and factors (age, escolarity, socioeconomic level, geographic area, region, ethnic group, tobacco habits), and body mass index according on the weeks of gestation were determined. There were made normality tests, measure comparisons, and association between logistic regression models. Results: the prevalence of Iron deficiency anemia (hemoglobin < 11 g/dL and ferritin < 12 mu g/L) was 11.0% (CI95% = 9.7-12.6). The highest prevalence was found in pregnant women without any escolarity (19.4%; CI95% = 8.0-33.3), women in a socioeconomic level I (12.7%; CI95% = 10.3-14.9), that live in the Atlantic or Pacific regions (16.0%; CI95% = 12.0-20.4 and 12.7%; CI95% = 8,3-17,1 respectively), and Afro-Colombian women (18.6%; IC95% = 12.1-23.9). Iron deficiency anemia was associated with living in the Atlantic region OR 7.21 (CI95% 1.71-30.33), Oriental OR 4.50 (CI95% 1.01-20.04), Pacific OR 5.51 (CI95% 1.27-23.88), national territory OR 4.37 (CI95% 1.03-18.57) and belonging to an Afro-Colombian ethnic group OR 2.19 (CI95% 1.40-3.42). Conclusions: the studied population presents a high prevalence of iron deficiency anemia and it is associated with the residency region and ethnic group.

10 November 2022 in Journal of Clinical Medicine
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MCMarta Cano-Castellote
Marta Cano-Castellote
Diego Fernando Afanador-RestrepoDiego Fernando Afanador-Restrepo
Diego Fernando Afanador-Restrepo
Jhonatan Gonzalez-SantamariaJhonatan Gonzalez-Santamaria
Jhonatan Gonzalez-Santamaria
CRCarlos Rodríguez-López
Carlos Rodríguez-López
MCMaría Yolanda Castellote-Caballero
María Yolanda Castellote-Caballero
Agustín Aibar-AlmazánAgustín Aibar-Almazán
Agustín Aibar-Almazán
Spontaneous coronary artery dissection (SCAD) is an infrequent cause of nonobstructive ischemic heart disease in previously healthy young women and therefore is not usually considered in differential diagnoses. The overall incidence of SCAD in angiographic series is between 0.28 and 1.1%, with a clear predominance in young, healthy women (70%) of whom approximately 30% are in the postpartum period. In the United Kingdom, between 2008 and 2012, SCAD was the cause of 27% of acute myocardial infarctions during pregnancy, with a prevalence of 1.81 per 100,000 pregnancies. Regarding the mechanism of arterial obstruction, this may be due to the appearance of an intramural hematoma or to a tear in the intima of the arteries, both spontaneously. Although multiple diagnostic methods are available, it is suggested to include an appropriate anamnesis, an electrocardiogram in the first 10 min after admission to the service or the onset of symptoms, and subsequently, a CT angiography of the coronary arteries or urgent coronary angiography if the hemodynamic status of the patient allows it. Treatment should be individualized for each case; however, the appropriate approach is generally based on two fundamental pillars: conservative medical treatment with antiplatelet agents, beta-blockers, and nitrates, and invasive treatment with percutaneous coronary intervention for stent implantation or balloon angioplasty, if necessary.

7 May 2019 in PLOS ONE
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DRDavid Rincon-pabon
David Rincon-pabon
YUYeraldin Urazán-Hernández
Yeraldin Urazán-Hernández
Jhonatan Gonzalez-SantamariaJhonatan Gonzalez-Santamaria
Jhonatan Gonzalez-Santamaria
To determine the association between the time spent watching television and the sociodemographic characteristics with the presence of overweight and obesity in Colombian adolescents. Secondary analysis of the information obtained in the National Survey of the Nutritional Situation 2010 of Colombia, in a probabilistic sample of 18177 adolescents with an age range between 13 and 17 years. The time spent watching television and / or videogames and sociodemographic factors was determined. Anthropometric markers and body composition were recorded. Associations were established through logistic regression models. The prevalence of overweight was 13.0% (95% CI 12.4–13.8) and obesity was 3.0% (95% CI 2.8–3.3). The prevalences of overweight and obesity were higher in adolescent women [16.6% (95% CI 15.8–17.5) and 3.4% (95% CI 3.1–3.7), respectively]. Overweight and obesity were associated with being female [OR 1.94 (95%CI 1.77–2.12) and OR 1.29 (95%CI 1.09–1.53), respectively], high socioeconomic level [OR 1.22 (95%CI 1.10–1.36) and OR 1.47 (95%CI 1.19–1.81), respectively], reside in urban area [OR 1.13 (95%CI 1.03–1.24) and OR 1.47 (95%CI 1.21–1.79), respectively]. Being indigenous was associated with being overweight [OR 1.25 (95%CI 1.10–1.42)], while being Afro-Colombian was associated with obesity [OR 1.33 (95%CI 1.05–1.69)]. Watching television and / or video games for two or more hours a day [OR1.17 (95%CI 1.06–1.30)] was associated with being overweight; whereas watching television every day of the week was associated with obesity [OR 1.66 (95%CI 1.13–2.43)]. The population studied has a significant prevalence of overweight and obesity, being overweight is associated with being a woman, a high socioeconomic status, residing in an urban area, having an indigenous ethnicity, watching television for three days during the week and looking at more than two hours of television in a day; Obesity is associated with being a woman, a medium-high and high socioeconomic status, residing in an urban area, Afro-Colombian ethnicity, watching television at least once in the last week and watching television every day during the last week.

29 November 2020 in Healthcare
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Jhonatan Gonzalez-SantamariaJhonatan Gonzalez-Santamaria
Jhonatan Gonzalez-Santamaria
Jesús Gilberto Arámburo-GálvezJesús Gilberto Arámburo-Gálvez
Jesús Gilberto Arámburo-Gálvez
CCCarlos eduardo Beltrán Cárdenas
Carlos eduardo Beltrán Cárdenas
JMJosé Antonio Mora-melgem
José Antonio Mora-melgem
OSOscar Gerardo Figueroa Salcido
Oscar Gerardo Figueroa Salcido
FCFrancisco Cabrera-Chávez
Francisco Cabrera-Chávez
There are no epidemiological data about food-dependent exercise-induced anaphylaxis (FDEIA) in Latin America. Our aim was to design, assess, and validate a questionnaire to identify potential FDEIA cases and/or estimate its prevalence by self-report. Questions were included in the instrument to address the main symptoms of FDEIA, type/intensity of physical activity, and anaphylaxis. The instrument’s clarity, comprehension and repeatability were evaluated. These evaluations were carried out by Hispanic people (Argentinians/Colombians/Mexicans/Peruvians), including nine individuals with medical diagnosis of FDEIA, and Brazilians. The Flesch–Kincaid score was calculated using the INFLESZ software. The instrument was translated from Spanish to Brazilian Portuguese following the translation back-translation procedure. The participants rated the two versions of the questionnaire as clear and comprehensible (three-point ordinal scale) and very easy to understand [0.33; average (scale 0–10)]. For these evaluations, the Kendall’s W coefficient showed strong agreement among raters (W = 0.80; average). The Flesch–Kincaid score was 63.5 in average (documents considered as readable). The Cohen’s Kappa coefficient showed almost perfect agreement in repeatability (0.88; average). The validation process of two versions of an instrument, used to identify potential FDEIA cases, was successfully carried out and it was found applicable to Latin American countries for generating epidemiological data.