Christian Nicholas

Dr. Christian Nicholas


Research Focus & Metrics

Academic Career Length

57Years (1970-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 June 2013 in Alcohol, Clinical and Experimental Research
Verified
Journal Article
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PDF file
JCJulia K. M. Chan
Julia K. M. Chan
JTJohn Trinder
John Trinder
HAHolly E. Andrewes
Holly E. Andrewes
ICIan M. Colrain
Ian M. Colrain
CNChristian Nicholas
Christian Nicholas

1 April 2015 in Journal of Affective Disorders
Verified
Journal Article
Closed access
JWJoanna M. Waloszek
Joanna M. Waloszek
MBMichelle L. Byrne
Michelle L. Byrne
MWMichael J. Woods
Michael J. Woods
CNChristian Nicholas
Christian Nicholas
BBBei Bei
Bei Bei
JTJohn Trinder
John Trinder

1 October 2021 in Sleep Medicine Reviews
Verified
Journal Article
Closed access
MSMaya Schenker
Maya Schenker
LNLuke Ney
Luke Ney
LMLisa N. Miller
Lisa N. Miller
KFKim L. Felmingham
Kim L. Felmingham
CNChristian Nicholas
Christian Nicholas
AJAmy S. Jordan
Amy S. Jordan

CWCandice Wen
Candice Wen
CNChristian Nicholas
Christian Nicholas
SCSandy Clarke-Errey
Sandy Clarke-Errey
MHMark Howard
Mark Howard
JTJohn Trinder
John Trinder
AJAmy S. Jordan
Amy S. Jordan
Background: Aviation pilots and cabin crew regularly undertake shift work, and may experience circadian disruption, restricted sleep, sleepiness and impaired health. Research on aviation fatigue and sleepiness has focused on pilots, with less being known about cabin crew. This study aimed to identify likely predictors of fatigue, sleepiness, shift work disorder (SWD) and depression in cabin crew. Methods: An online anonymous survey was distributed to active cabin crew around the world. It measured sleepiness, fatigue, and screened for insomnia, depression and SWD. Information on individuals’ habits and work schedules were collected. Results: 930 valid responses were analysed. 63.5% of the sample had abnormal levels of fatigue and 46.9% experienced excessive daytime sleepiness. 68.0% were at risk for SWD, 57.7% screened positive for insomnia, and 40.0% for depression. Caffeine and use of alcohol and drugs for sleep were independently associated with insomnia and SWD (p < 0.05), whereas, type of route (international, domestic, both) and number of duty days per week predicted fatigue (p < 0.05). Conclusions: Cabin crew had a high prevalence of fatigue, sleepiness and elevated risk for SWD, insomnia and depression. Many cabin crew engaged in behaviours detrimental to good sleep hygiene, highlighting targets for future interventional studies.

16 January 2015 in Alcohol, Clinical and Experimental Research
Verified
Journal Article
Closed access
PDF file
JCJulia K. M. Chan
Julia K. M. Chan
JTJohn Trinder
John Trinder
ICIan M. Colrain
Ian M. Colrain
CNChristian Nicholas
Christian Nicholas

5 June 2021 in Behavioral Sleep Medicine
Verified
Journal Article
Closed access
CJClaire A. Jenkins
Claire A. Jenkins
LTLucy C. F. Tiley
Lucy C. F. Tiley
ILIsabella Lay
Isabella Lay
JHJessica A. Hartmann
Jessica A. Hartmann
JCJulia K. M. Chan
Julia K. M. Chan
CNChristian Nicholas
Christian Nicholas
Demonstrating inter-device reliability is essential to use devices interchangeably, and accurately integrate, interpret, or compare data from different actigraphs. Despite this, there is a paucity of comparative literature over a timeframe exceeding one night. The aims of this study were to determine an optimal wake threshold for GENEActiv and to evaluate the concordance between Actiwatch-2 and GENEActiv using a common algorithm (Phillips Respironics). Data were collected from 33 individuals (20 female) aged 20–35 years (M= 25.33, SD = 4.69) across a total 213 nights. Participants wore both devices simultaneously and continuously for seven days. The sleep parameters of interest were: total sleep time, sleep efficiency, sleep onset latency, and wake after sleep onset. Exploratory analyses of sensitivity, specificity, overall accuracy, mean bias, and paired samples t-tests indicated an optimal wake threshold of 115 for GENEActiv, compared with Actiwatch-2 at the 40 (medium, default) threshold. Using these thresholds, sensitivity, and overall accuracy of GENEActiv were both good (86% and 78%, respectively), however specificity was relatively low (40%). There were no significant inter-device differences for any sleep parameters, and all absolute mean biases were small. Overall, the findings from this study provide the first empirical evidence to support the reliability of GENEActiv against Actiwatch-2 over multiple nights using a common algorithm with device-specific wake thresholds.