Ilaria Giambuzzi

Dr. Ilaria Giambuzzi

Centro Cardiologico Monzino, IRCCS, Milan, Italy
orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 December 2016 in Journal of Cardiothoracic and Vascular Anesthesia
Verified
Journal Article
Closed access
EBElena Bignami
Elena Bignami
MGMarcello Guarnieri
Marcello Guarnieri
FSFrancesco Saglietti
Francesco Saglietti
ABAlessandro Belletti
Alessandro Belletti
CTCinzia Trumello
Cinzia Trumello
OAOttavio Alfieri
Ottavio Alfieri

1 January 2020 in The Annals of Thoracic Surgery
Verified
Journal Article
Closed access
ELElisabetta Lapenna
Elisabetta Lapenna
MBMichele De Bonis
Michele De Bonis
IGIlaria Giambuzzi
Ilaria Giambuzzi
BFBenedetto Del Forno
Benedetto Del Forno
SRStefania Ruggeri
Stefania Ruggeri
SBStefano Benussi
Stefano Benussi

Verified
Journal Article
Open access
PDF file
IGIlaria Giambuzzi
Ilaria Giambuzzi
GBGiorgia Bonalumi
Giorgia Bonalumi
Michele Di MauroMichele Di Mauro
Michele Di Mauro
MRMaurizio Roberto
Maurizio Roberto
SCSilvia Corona
Silvia Corona
MZMarco Zanobini
Marco Zanobini
The Commando procedure is challenging, and aims to replace the mitral valve, the aortic valve and the aortic mitral curtain, when the latter is severely affected by pathological processes (such as infective endocarditis or massive calcification). Given the high complexity, it is seldomly performed. We aim to review the literature on early (hospitalization and up to 30 days) and long-term (at least 3 years of follow-up) results. Bibliographical research was performed on PubMed and Cochrane with a dedicated string. Papers regarding double valve replacement or repair in the context of aortic mitral curtain disease were included. The metaprop function was used to assess early survival and complications (pacemaker implantation, stroke and bleeding). Nine papers (540 patients, median follow-up 41 (IQR 24.5–51.5) months) were included in the study. Pooled proportion of early mortality, stroke, pacemaker implant and REDO for bleeding were, respectively 16.2%, 7.8%, 25.1% and 13.1%. The long-term survival rate ranged from 50% to 92.2%. Freedom from re-intervention was as high as 90.9% when the endocarditis was not the first etiology and 78.6% in case of valvular infection (one author had 100%). Freedom from IE recurrences reached 85% at 10 years. Despite the high mortality, the rates of re-intervention and infective endocarditis recurrences following the Commando procedure are satisfactory and confirm the need for an aggressive strategy to improve long-term outcomes.

23 February 2017 in European Journal of Cardio-Thoracic Surgery
Verified
Journal Article
Closed access
PDF file
MBMichele MDB De Bonis
Michele MDB De Bonis
ELElisabetta Lapenna
Elisabetta Lapenna
SSStefania Di Sanzo
Stefania Di Sanzo
BFBenedetto Del Forno
Benedetto Del Forno
Federico PappalardoFederico Pappalardo
Federico Pappalardo
OAOttavio Alfieri
Ottavio Alfieri
OBJECTIVES: To report the long-term results of the clover technique for the treatment of complex forms of tricuspid regurgitation (TR). METHODS: Ninety-six consecutive patients (mean age 60 ± 16.4, left ventricular ejection fraction 58 ± 8.8%) with severe or moderately-severe TR due to important leaflets prolapse/flail (81 patients), tethering (13 patients) or mixed (2 patients) lesions underwent clover repair combined with annuloplasty. The aetiology of TR was degenerative in 74 cases (77.1%), post-traumatic in 9 (9.4%) and secondary to dilated cardiomyopathy in 13 (13.5%). All patients but 3 (96.8%) underwent ring (59 patients, 61.5%) or suture (34 patients, 35.4%) annuloplasty. Concomitant procedures (mainly mitral surgery) were performed in 82 patients (85.4%). RESULTS: Hospital mortality was 7.2%. At hospital discharge 92 (95.8%) patients had no or mild TR. Follow-up was 98% complete (median 9 years, interquartile range 5.1; 10.9). At 12 years the overall survival was 71.6 ± 7.22% and the cumulative incidence function of cardiac death with non-cardiac death as competing risk 16 ± 4.1% [95% confidence interval (95% CI) 9.5–25.7]. At 12 years the cumulative incidence function of TR ≥ 3+ and TR ≥ 2+ with death as competing risk were 1.2 ± 1.2% (95% CI 0.1–5.8) and 28 ± 7.7% (95% CI 14.3–43.5), respectively. Preoperative left ventricular ejection fraction (hazard ratio 0.9, CI 0.9–1, P = 0.05) and previous cardiac surgery (hazard ratio 2.7, 95% CI 1–7.1, P = 0.03) were predictors of recurrent TR ≥ 2+ at univariable but not at multivariable analysis. CONCLUSIONS: Complex forms of TR due to severe prolapse or tethering of the leaflets can be effectively treated with the clover technique with very satisfactory long-term results and extremely low recurrence of severe TR.

25 June 2020 in European Journal of Cardio-Thoracic Surgery
Verified
Journal Article
Closed access
GBGiorgia Bonalumi
Giorgia Bonalumi
IGIlaria Giambuzzi
Ilaria Giambuzzi
ABAlessandro BARBONE
Alessandro BARBONE
CRCamilla Ranieri
Camilla Ranieri
LCLaura Cavallotti
Laura Cavallotti
FAFrancesco Alamanni
Francesco Alamanni
OBJECTIVES: During the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pandemic, Northern Italy had to completely reorganize its hospital activity. In Lombardy, the hub-and-spoke system was introduced to guarantee emergency and urgent cardiovascular surgery, whereas most hospitals were dedicated to patients with coronavirus disease 2019 (COVID-19). The aim of this study was to analyse the results of the hub-and-spoke organization system. METHODS: Centro Cardiologico Monzino (Monzino) became one of the four hubs for cardiovascular surgery, with a total of eight spokes. SARS-CoV-2 screening became mandatory for all patients. New flow charts were designed to allow separated pathways based on infection status. A reorganization of spaces guaranteed COVID-19-free and COVID-19-dedicated areas. Patients were also classified into groups according to their pathological and clinical status: emergency, urgent and non-deferrable (ND). RESULTS: A total of 70 patients were referred to the Monzino hub-and-spoke network. We performed 41 operations, 28 (68.3%) of which were emergency/urgent and 13 of which were ND. The screening allowed the identification of COVID-19 (three patients, 7.3%) and non-COVID-19 patients (38 patients, 92.7%). The newly designed and shared protocols guaranteed that the cardiac patients would be divided into emergency, urgent and ND groups. The involvement of the telematic management heart team allowed constant updates and clinical discussions. CONCLUSIONS: The hub-and-spoke organization system efficiently safeguards access to heart and vascular surgical services for patients who require ND, urgent and emergency treatment. Further reorganization will be needed at the end of this pandemic when elective cases will again be scheduled, with a daily increase in the number of operations.

27 December 2018 in Catheterization and Cardiovascular Interventions
Verified
Journal Article
Closed access
PDF file
NBNicola Buzzatti
Nicola Buzzatti
PDPaolo Denti
Paolo Denti
ISIside Stella Scarfò
Iside Stella Scarfò
IGIlaria Giambuzzi
Ilaria Giambuzzi
DSDavide Schiavi
Davide Schiavi
OAOttavio Alfieri
Ottavio Alfieri