I am an immunologist with a deep and long-lasting interest in how the immune response shapes cancer and autoimmune disease. I am leveraging the immune-suppressive populations that restrain anti-tumor immunity in pancreatic cancer and malignant melanoma, with developing new immune-based therapy options for these deadly malignancies. I acquired the knowledge, training and experience in the field of immunology to effectively carry out research in basic immunology for better translation of research findings to clinical applications. I worked on molecular mechanism of T cell differentiation associated with auto-inflammatory responses. I proposed that the regulatory T cell (Treg) function and cytokine signaling dictates the balance between Treg and Th17 cells. In addition to many first-author publications, I have written several collaborative co-authored peer-reviewed publications in collaboration during my research studies. Currently, I am working on cellular and molecular mechanisms of B cell-mediated immune responses during pancreatic cancer and malignant melanoma initiation and progression.