The data about the incidence and risk factors for surgical site infections (SSIs) following total joint arthroplasty (TJA) in middle-income countries are still scant. The aim of this study was to assess the incidence and risk factors associated with 30-day SSIs following total hip arthroplasty (THA) and total knee arthroplasty (TKA). The study was conducted at the Clinic for Orthopedic Surgery and Traumatology, Clinical Center of Serbia (CCS) in Belgrade, from May 2016 to April 2018. All patients undergoing THA or TKA were followed throughout hospitalization until day 30 after discharge. Of the 1073 admitted patients, 459 had THA and 230 had TKA. The incidence rate of surgical site infections (SSIs) among the patients who underwent THA was 5.4%, which is 3.8 per 1000 postoperative patient-days, while the rate among those who had TKA was 4.8%, i.e., 3.4 per 1000 postoperative patient-days. Out of the 36 SSIs, 15 were deep and 21 were superficial incisional ones. Among the variables examined, the independent risk factors for SSIs after THA were the American Society of Anesthesiologists (ASA) score > 2 (RR = 3.17; 95% CI—1.26–8.02), smoking (RR = 3.14; 95% CI—1.26–7.82) and peripheral vascular disease (PVD) (RR = 6.09; 95% CI—2.35–15.77), and after TKA, only PVD (RR = 3.87; 95% CI—1.09–13.76) was the risk factor. Incidence rates of SSIs after arthroplasty are higher compared to reports from developed countries. Therefore, it is necessary to enhance infection prevention and control measures with strict control of modifiable risk factors.
We aimed to assess awareness, knowledge, and attitudes of healthy pregnant women towards human papillomavirus (HPV), to estimate factors associated with a positive attitude towards HPV immunization and to assess the uptake of the vaccine among their children. A cross-sectional study was conducted at the University Clinic of Gynecology and Obstetrics, Belgrade, Serbia among pregnant women attending their regular gynecological check-ups at the 12th gestational week. Knowledge about HPV and HPV vaccine was assessed using a specifically designed 12-item and 5-item questionnaires. Out of total 265 included women, 79.3% had heard of HPV, and 37.5% knew that HPV vaccine exists. HPV vaccine knowledge score was associated with higher odds for a positive attitude towards vaccination of both female (OR = 4.10, 95% CI 1.50–11.29) and male (OR = 3.71, 95% CI 1.52–9.01) child. The number of children (OR = 1.32, 95% CI 1.04–1.67) and high vaccine knowledge score (OR = 1.64 95% CI 1.13–2.39) were independent predictors associated with willingness to vaccinate child against HPV. The gynecologist was the preferable point of reference for information seeking about the HPV vaccine. Despite relatively high HPV awareness and knowledge among pregnant women in Serbia, about one-third of them are HPV vaccine aware, and are willing to vaccinate their children against HPV.
Background/Objectives: Seasonal variations in mortality rates are well-documented, particularly during the winter months when mortality typically increases. This rise in mortality, ranging from 5% to 25%, is often associated with chronic cardiovascular and respiratory diseases. Understanding these seasonal fluctuations is essential for guiding public health interventions. This study analyzes mortality rates and excess mortality in Belgrade from March 2020 to May 2023, focusing on the impact of the COVID-19 pandemic on overall mortality trends. The primary objective of this study is to assess the impact of the COVID-19 pandemic on mortality rates in Belgrade during the study period. The first secondary objective is to evaluate seasonal variations in mortality, with a focus on the 10.57% overall increase in mortality, and to highlight the 34.23% rise in winter mortality recorded in 2020. The second secondary objective is to assess the effectiveness of public health measures in mitigating excess mortality during this period. Methods: A descriptive epidemiological approach was used to analyze monthly mortality data from the City Bureau of Statistics. Mortality rates were standardized using direct standardization and compared winter (December-February) and non-winter (March-November) periods. Trends, percentage increases, and age-specific mortality were analyzed based on the 2011 census methodology. Results: Mortality rates in Belgrade ranged from 1115.67 to 1267.19 deaths per 100,000 inhabitants, with an average of 1205.62. Standardized mortality rates ranged from 936.49 to 1111.67, averaging 1021.64. The winter months showed higher mortality, averaging 1716 deaths per 100,000, compared to 1558 in the non-winter months. Conclusions: The winter months exhibited significantly higher mortality rates, likely exacerbated by the COVID-19 pandemic. Targeted public health policies and interventions are necessary to reduce seasonal mortality risks during future public health crises.