Major depressive disorder is the leading cause of disability worldwide.
1 In 2016, the US Preventive Services Task Force (USPSTF) newly recommended universal depression screening in the general adult population, with the expectation that screening would be linked to appropriate treatment.
2 USPSTF recognized that staff-assisted depression care directed at ensuring accurate diagnosis, appropriate follow-up, and effective treatment conferred substantial improvement in clinical outcomes and was increasingly available in primary care settings. Yet, others have disagreed
3 and cited that evidence supporting the benefits of universal depression screening is too limited. For example,
4 2013 guidelines from the Canadian Task Force on Preventive Health Care recommended against routine depression screening to avoid depression overdiagnosis. Knowledge gaps in depression screening remain because few health care systems have been able to pragmatically study the population-based trajectory from screening to follow-up and treatment for those who have depression.