Leonardo Fernandes Fraceto

Dr. Leonardo Fernandes Fraceto

orcid

Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 September 2018 in Journal of Nanobiotechnology
Verified
Journal Article
Open access
PDF file
Jayanta Kumar PatraJayanta Kumar Patra
Jayanta Kumar Patra
GDGITISHREE DAS
GITISHREE DAS
LFLeonardo Fernandes Fraceto
Leonardo Fernandes Fraceto
Estefânia Vangelie Ramos CamposEstefânia Vangelie Ramos Campos
Estefânia Vangelie Ramos Campos
MRMaria del Pilar Rodriguez-Torres
Maria del Pilar Rodriguez-Torres
Han-Seung ShinHan-Seung Shin
Han-Seung Shin
Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.) in the treatment of various diseases. The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (e.g., natural products) and selective diagnosis through disease marker molecules. The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed. In addition, we have included information regarding the trends and perspectives in nanomedicine area.

16 March 2023 in Journal of Cleaner Production
Verified
Journal Article
Open access
Muhammad MujtabaMuhammad Mujtaba
Muhammad Mujtaba
LFLeonardo Fernandes Fraceto
Leonardo Fernandes Fraceto
MFMahyar Fazeli
Mahyar Fazeli
Sritama MukherjeeSritama Mukherjee
Sritama Mukherjee
SSSusilaine Maira Savassa
Susilaine Maira Savassa
FVFrancisco Vilaplana
Francisco Vilaplana

22 March 2016 in Frontiers in Environmental Science
Verified
Journal Article
Open access
LFLeonardo Fernandes Fraceto
Leonardo Fernandes Fraceto
RGRenato Grillo
Renato Grillo
GMGerson A. de Medeiros
Gerson A. de Medeiros
VSViviana Scognamiglio
Viviana Scognamiglio
Giuseppina ReaGiuseppina Rea
Giuseppina Rea
CBCecilia Bartolucci
Cecilia Bartolucci
Recent scientific data indicate that nanotechnology has the potential to positively impact the agrifood sector, minimizing adverse problems of agricultural practices on environment and human health, improving food security and productivity (as required by the predicted rise in global population), while promoting social and economic equity. In this context, we select and report on recent trends in nanomaterial-based systems and nanodevices that could provide benefits on the food supply chain specifically on sustainable intensification, and management of soil and waste. Among others, nanomaterials for controlled-release of nutrients, pesticides and fertilizers in crops are described as well as nanosensors for agricultural practices, food quality and safety.

1 December 2014 in Biotechnology Advances
Verified
Journal Article
Closed access
JOJhones Luiz de Oliveira
Jhones Luiz de Oliveira
Estefânia Vangelie Ramos CamposEstefânia Vangelie Ramos Campos
Estefânia Vangelie Ramos Campos
MBMansi Bakshi
Mansi Bakshi
Purushothaman Chirakkuzhyil AbhilashPurushothaman Chirakkuzhyil Abhilash
Purushothaman Chirakkuzhyil Abhilash
LFLeonardo Fernandes Fraceto
Leonardo Fernandes Fraceto

1 August 2014 in Journal of Hazardous Materials
Verified
Journal Article
Closed access
RGRenato Grillo
Renato Grillo
APAnderson E.S. Pereira
Anderson E.S. Pereira
CNCaroline S. Nishisaka
Caroline S. Nishisaka
RLRenata Lima
Renata Lima
KOKathleen Oehlke
Kathleen Oehlke
LFLeonardo Fernandes Fraceto
Leonardo Fernandes Fraceto

20 January 2021 in Nanomaterials
Verified
Journal Article
Open access
PDF file
APAnderon Pereira
Anderon Pereira
Halley Caixeta de OliveiraHalley Caixeta de Oliveira
Halley Caixeta de Oliveira
LFLeonardo Fernandes Fraceto
Leonardo Fernandes Fraceto
CSCatherine Santaella
Catherine Santaella
Our agriculture is threatened by climate change and the depletion of resources and biodiversity. A new agriculture revolution is needed in order to increase the production of crops and ensure the quality and safety of food, in a sustainable way. Nanotechnology can contribute to the sustainability of agriculture. Seed nano-priming is an efficient process that can change seed metabolism and signaling pathways, affecting not only germination and seedling establishment but also the entire plant lifecycle. Studies have shown various benefits of using seed nano-priming, such as improved plant growth and development, increased productivity, and a better nutritional quality of food. Nano-priming modulates biochemical pathways and the balance between reactive oxygen species and plant growth hormones, resulting in the promotion of stress and diseases resistance outcoming in the reduction of pesticides and fertilizers. The present review provides an overview of advances in the field, showing the challenges and possibilities concerning the use of nanotechnology in seed nano-priming, as a contribution to sustainable agricultural practices.