Throughout their life span, plants have to face unfavourable environmental conditions including abiotic and biotic stress factors. Plants respond to these growth limiting factors by perceiving stress-related patterns or signals and subsequent activation of specific defence mechanism involving genes and regulatory elements. Will it be possible to induce defence-related physiological and cellular incitement state in a more robust and precise way? My research is focused to answer this question by exploiting seaweed-derived natural priming substances, i.e. Biostimulants, and to unravel the molecular basis of defence priming in Arabidopsis and crop plants.