I am interested in investigating the effect of cellular factors on various viral pathogenesis and chronic inflammatory diseases and finding therapeutic strategies. During the period of my PhD to post-Doc fellow, my research specifically focuses on dissecting the molecular mechanisms underlying the processes of viral infection and lung damage caused by influenza virus, such as pneumonia and acute respiratory distress syndrome. Recently, I devote to research on host factors such as prothymosin α and O-Linked N-Acetylglucosamine (GlcNAc) Transferase that participate in megakaryocyte differentiation and platelet activation/destruction associated with dengue induced thrombocytopenia. In these studies, I use viral vector, in vitro approaches, animal models and clinical samples to dissect disease development/pathogenesis and identify novel therapeutic targets.