Anna Druzina

Dr. Anna Druzina

A.N.Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences
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Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2020 in Biomaterials
Verified
Journal Article
Closed access
ZSZheyu Shen
Zheyu Shen
TLTing Liu
Ting Liu
ZYZhen Yang
Zhen Yang
ZZZijian Zhou
Zijian Zhou
WTWei Tang
Wei Tang
XCXiaoyuan Chen
Xiaoyuan Chen
1 August 2021 in Russian Chemical Reviews
Verified
Journal Article
Closed access
ADAnna Druzina
Anna Druzina
ASAkim Shmalko
Akim Shmalko
Igor B. SivaevIgor B. Sivaev
Igor B. Sivaev
Vladimir BregadzeVladimir Bregadze
Vladimir Bregadze
The rapid progress in the chemistry of carboranes and other polyhedral boron compounds makes the development of methods for the synthesis of their various functional derivatives a high priority. The formation of cyclic oxonium derivatives followed by the ring opening is one of the most efficient methods for the preparation of these compounds. This review addresses the data on the use of the nucleophilic ring opening of cyclic oxonium derivatives based on cobalt and iron bis(dicarbollides), which have been extensively studied in recent years. Reactions involving O-, N-, S-, P- and C-nucleophiles are considered as a route to the targeted synthesis of a wide range of organic boron derivatives, in particular various boron-containing biologically active compounds. Possible applications of the reaction products are discussed.The bibliography includes 197 references.
29 November 2016 in Russian Chemical Reviews
Verified
Journal Article
Closed access
ADAnna Druzina
Anna Druzina
VBV I Bregadze
V I Bregadze
AMA F Mironov
A F Mironov
ASA A Semioshkin
A A Semioshkin
3 May 2022 in Molecules
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Journal Article
Open access
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ADAnna Druzina
Anna Druzina
GNGrammatikova Natalia
Grammatikova Natalia
OZOlga B. Zhidkova
Olga B. Zhidkova
NNNatalia A. Nekrasova
Natalia A. Nekrasova
NDNadezhda Dudarova
Nadezhda Dudarova
Vladimir BregadzeVladimir Bregadze
Vladimir Bregadze
A series of novel conjugates of cobalt bis(dicarbollide) and closo-dodecaborate with curcumin were synthesized by copper(I)-catalyzed azide-alkyne cycloaddition. These conjugates were tested for antibacterial activity. It was shown that all derivatives are active when exposed to Bacillus cereus ATCC 10702 and are not active against Gram-negative microorganisms and Candida albicans at the maximum studied concentration of 1000 mg/L. The conjugate of alkynyl-curcumin with azide synthesized from the tetrahydropyran derivative of cobalt bis(dicarbollide) exhibited activity against Gram-positive microorganisms: Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 29212 and the clinical isolate MRSA 17, that surpassed curcumin by 2–4 times.
1 June 2020 in Russian Chemical Bulletin
Verified
Journal Article
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ADAnna Druzina
Anna Druzina
OZO. B. Zhidkova
O. B. Zhidkova
IKI. D. Kosenko
I. D. Kosenko
22 November 2019 in Mendeleev Communications
Verified
Journal Article
Closed access
ADAnna Druzina
Anna Druzina
ASAkim V. Shmalko
Akim V. Shmalko
EAEkaterina P. Andreichuk
Ekaterina P. Andreichuk
OZOlga B. Zhidkova
Olga B. Zhidkova
IKIrina D. Kosenko
Irina D. Kosenko
Vladimir BregadzeVladimir Bregadze
Vladimir Bregadze
New conjugates of cholesterol and cobalt bis(dicarbollide) were synthesized using ‘click’ cycloaddition of 3b-(2-azidoethyl) cholest-5-ene and acetylene-equipped cobalt bis(dicarbollides). The synthesized boronated cholesterols can be of interest for liposomal drug delivery for boron neutron capture therapy of cancer.