Dario Kremer

Dr. Dario Kremer

Pharmaceutical Botanical Garden Fran Kušan, University of Zagreb, 10000 Zagreb, Croatia
orcid

Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
19 November 2015 in Current Drug Targets
Verified
Journal Article
Closed access
Dario KremerDario Kremer
Dario Kremer
IKIztok Košir
Iztok Košir
MKMarijana Končić
Marijana Končić
AČAndreja Čerenak
Andreja Čerenak
TPTanja Potočnik
Tanja Potočnik
Ivan KosalecIvan Kosalec
Ivan Kosalec
Satureja montana L. and S. subspicata Vis. (Lamiaceae) are used for centuries in traditional medicine of Balcanic people in the healing of the lymphatic nodule and respiratory system inflammation. In this paper the amount of total phenols and flavonoids (analyzed by UV/Vis spectrophotometry), phenolic compounds profile (analyzed by HPLC), antimicrobial and antioxidant activities were studied in samples collected in seven per species populations of S. montana and S. subspicata in Croatia. Eight phenolic compounds (rutin, quercetin, caffeic, p-coumaric, ellagic, protocatehuic, rosmarinic, and syringic acid) were identified and quantified using HPLC in methanolic and ethanolic extracts. Results showed that both species contained polyphenolics and other antioxidant compounds with chelating and radical-scavenging properties. The extracts prepared from both species showed broad spectrum of antimicrobial activity on in vitro tested microbial species (Staphylococcus aureus, Escherichia coli, Candida albicans, C. dubliniensis, C. krusei, C. glabrata, C. parapsilosis, and Microsporum gypseum).

19 December 2012 in Chemistry & Biodiversity
Verified
Journal Article
Closed access
PDF file
Valerija DunkicValerija Dunkic
Valerija Dunkic
Dario KremerDario Kremer
Dario Kremer
IMIvna Dragojević Müller
Ivna Dragojević Müller
ESEdith Stabentheiner
Edith Stabentheiner
SKSunčica Kuzmić
Sunčica Kuzmić
NBNada Bezić
Nada Bezić

16 December 2021 in TURKISH JOURNAL OF AGRICULTURE AND FORESTRY
Verified
Journal Article
Closed access
SBSnježana Bolarić
Snježana Bolarić
IMIvna Dragojević Müller
Ivna Dragojević Müller
AVAleš Vokurka
Aleš Vokurka
Dubravka Vitali ČepoDubravka Vitali Čepo
Dubravka Vitali Čepo
MRMirko Ruščić
Mirko Ruščić
Dario KremerDario Kremer
Dario Kremer

1 August 2015 in Phytochemistry
Verified
Journal Article
Closed access
Dario KremerDario Kremer
Dario Kremer
SBSnježana Bolarić
Snježana Bolarić
DBDalibor Ballian
Dalibor Ballian
FBFaruk Bogunić
Faruk Bogunić
DSDanijela Stešević
Danijela Stešević
Valerija DunkicValerija Dunkic
Valerija Dunkic

5 April 2019 in Molecules
Verified
Journal Article
Open access
PDF file
EVElma Vuko
Elma Vuko
GRGordana Rusak
Gordana Rusak
Valerija DunkicValerija Dunkic
Valerija Dunkic
Dario KremerDario Kremer
Dario Kremer
Ivan KosalecIvan Kosalec
Ivan Kosalec
NBNada Bezić
Nada Bezić
The present results dealing with the antiphytoviral activity of essential oil indicate that these plant metabolites can trigger a response to viral infection. The essential oil from Micromeria croatica and the main oil components β-caryophyllene and caryophyllene oxide were tested for antiphytoviral activity on plants infected with satellite RNA associated cucumber mosaic virus. Simultaneous inoculation of virus with essential oil or with the dominant components of oil, and the treatment of plants prior to virus inoculation, resulted in a reduction of virus infection in the local and systemic host plants. Treatment with essential oil changed the level of alternative oxidase gene expression in infected Arabidopsis plants indicating a connection between the essential oil treatment, aox gene expression and the development of viral infection.

19 November 2015 in Current Drug Targets
Verified
Journal Article
Closed access
Valerija DunkicValerija Dunkic
Valerija Dunkic
Ivan KosalecIvan Kosalec
Ivan Kosalec
IKIztok Kosir
Iztok Kosir
TPTanja Potocnik
Tanja Potocnik
ACAndreja Cerenak
Andreja Cerenak
Dario KremerDario Kremer
Dario Kremer
Tea made from Veronica spicata L. (syn. Pseudolysimachion spicatum (L.) Opiz, family Plantaginaceae) herb is used in traditional medicine as expectorant for cough and throat rinsing. To get insight into chemical compounds of V. spicata, the essential oil content (analysed by GC-FID and GC-MS), the content of phenolic compounds (analysed by HPLC), the content of macroelements and trace elements (analysed by ICP-AES), quantity of total phenols and total flavonoids (analysed by UV/Vis spectrophotometer), and antioxidant and antimicrobial properties were investigated. The main compounds of the essential oil were phytol (21.13%), heptacosane (10.22%) and pentacosane (8.91%). The most abundant investigated macroelement was K (8261 mg/kg) while Fe was the most represented element (32.49 mg/kg) among investigated micronutrients. Ten phenolic compounds (chrysin, rutin, quercitrin, quercitrin, and cichoric, ferulic, protocatehuic, rosmarinic, syringic and tannic acid) were identified and quantified. Additionally, V. spicata extract demonstrated notable radical-scavenging and chelating properties. The bacterial and fungal strains used in study were found to be susceptible toward methanolic and ethyl-acetate extracts with MIC values between 1.25 and 5.00 mg/mL using microdilution method. Aquose extracts were found to be antimicrobial inactive.