Esther Van Lieshout

Dr. Esther Van Lieshout

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Research Focus & Metrics

Academic Career Length

29Years (1998-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 September 2011 in Journal of Trauma: Injury, Infection & Critical Care
Verified
Journal Article
Closed access
KHKlaas A. Hartholt
Klaas A. Hartholt
EBEd F. van Beeck
Ed F. van Beeck
SPSuzanne Polinder
Suzanne Polinder
NVNathalie van der Velde
Nathalie van der Velde
ELEsther Van Lieshout
Esther Van Lieshout
PPPeter Patka
Peter Patka
Background: Fall incidents are a major cause of morbidity and mortality in older adults. The aim of this cohort study was to determine the incidence, costs, and quality of life for fall-related injuries in the older Dutch population presenting at the emergency department. Methods: Data on fall-related injuries in persons aged 65 years or older were retrieved from the Dutch Injury Surveillance System, which records injuries treated at the emergency department, and a patient follow-up survey conducted between 2003 and 2007. Injury incidence, discharge rates, healthcare costs, and quality of life measures were calculated. Results: Fall-related injuries were to the upper or lower limb in 70% of cases and consisted mainly of fractures (60%), superficial injuries (21%), and open wounds (8%). Falls led to a total healthcare cost of €474.4 million, which represents 21% of total healthcare expenses due to injuries. Both admitted and nonadmitted patients reported a reduced quality of life up to 9 months after the injury. Conclusions: Fall-related injuries in older adults are age and gender related, leading to high healthcare consumption, costs, and long-term reduced quality of life. Further implementation of falls prevention strategies is needed to control the burden of fall-related injuries in the aging population.

1 November 2020 in Injury
Verified
Journal Article
Closed access
SLSverre A.I. Loggers
Sverre A.I. Loggers
ELEsther Van Lieshout
Esther Van Lieshout
PJPieter Joosse
Pieter Joosse
MVMichael H.J. Verhofstad
Michael H.J. Verhofstad
HWHanna C. Willems
Hanna C. Willems

1 July 2013 in Orthopedics
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Journal Article
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SZStephanie M. Zielinski
Stephanie M. Zielinski
NKNoël L. Keijsers
Noël L. Keijsers
SPStephan F.E. Praet
Stephan F.E. Praet
MHMartin J. Heetveld
Martin J. Heetveld
MBMohit Bhandari
Mohit Bhandari
OIon behalf of the FAITH Trial Investigators
on behalf of the FAITH Trial Investigators
This study assesses femoral neck shortening and its effect on gait pattern and muscle strength in patients with femoral neck fractures treated with internal fixation. Seventy-six patients from a multicenter randomized controlled trial participated. Patient characteristics and Short Form 12 and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were collected. Femoral neck shortening, gait parameters, and maximum isometric forces of the hip muscles were measured and differences between the fractured and contralateral leg were calculated. Variables of patients with little or no shortening, moderate shortening, and severe shortening were compared using univariate and multivariate analyses. Median femoral neck shortening was 1.1 cm. Subtle changes in gait pattern, reduced gait velocity, and reduced abductor muscle strength were observed. Age, weight, and Pauwels classification were risk factors for femoral neck shortening. Femoral neck shortening decreased gait velocity and seemed to impair gait symmetry and physical functioning. In conclusion, internal fixation of femoral neck fractures results in permanent physical limitations. The relatively young and healthy patients in our study seem capable of compensating. Attention should be paid to femoral neck shortening and proper correction with a heel lift, as inadequate correction may cause physical complaints and influence outcome.

27 February 2017 in BMJ Open
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Journal Article
Open access
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ELEsther Van Lieshout
Esther Van Lieshout
ABA Siebe De Boer
A Siebe De Boer
DMDuncan Edward Meuffels
Duncan Edward Meuffels
PHP Ted Den Hoed
P Ted Den Hoed
CVCornelis H Van der Vlies
Cornelis H Van der Vlies
MVMichael H J Verhofstad
Michael H J Verhofstad
Introduction The American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score is among the most commonly used instruments for measuring the outcome of treatment in patients who sustained a complex ankle or hindfoot injury. It combines a clinician-reported and a patient-reported part. A valid Dutch version of this instrument is currently not available. Such a translated and validated instrument would allow objective comparison across hospitals or between patient groups, and with shown validity and reliability it may become a quality of care indicator in future. The main aims of this study are to translate and culturally adapt the AOFAS Ankle-Hindfoot Score questionnaire into Dutch according to international guidelines, and to evaluate the measurement properties of the AOFAS Ankle-Hindfoot Score-Dutch language version (DLV) in patients with a unilateral ankle or hindfoot fracture. Methods and analysis The design of the study will be a multicentre prospective observational study (case series) in patients who presented to the emergency department with a unilateral ankle or hindfoot fracture or (fracture) dislocation. A research physician or research assistant will complete the AOFAS Ankle-Hindfoot Score-DLV based on interview for the subjective part and a physical examination for the objective part. In addition, patients will be asked to complete the Foot Function Index (FFI) and the Short Form-36 (SF-36). Descriptive statistics (including floor and ceiling effects), internal consistency, construct validity, reproducibility (ie, test–retest reliability, agreement and smallest detectable change) and responsiveness will be assessed for the AOFAS DLV. Ethics and dissemination This study has been exempted by the Medical Research Ethics Committee (MREC) Erasmus MC (Rotterdam, the Netherlands). Each participant will provide written consent to participate and remain anonymised during the study. The results of the study are planned to be published in an international, peer-reviewed journal. Trial registration number NTR5613. pre-result.

1 July 2015 in Injury
Verified
Journal Article
Closed access
DHDennis Den Hartog
Dennis Den Hartog
JRJamie Romeo
Jamie Romeo
ARAkkie N. Ringburg
Akkie N. Ringburg
MVMichael H.J. Verhofstad
Michael H.J. Verhofstad
ELEsther Van Lieshout
Esther Van Lieshout

12 March 2022 in Injury
Verified
Journal Article
Open access
JOJolien Onsea
Jolien Onsea
ELEsther Van Lieshout
Esther Van Lieshout
CZCharalambos Zalavras
Charalambos Zalavras
JSJonathan Sliepen
Jonathan Sliepen
MDMelissa Depypere
Melissa Depypere
Willem‐Jan MetsemakersWillem‐Jan Metsemakers
Willem‐Jan Metsemakers
The recently developed fracture-related infection (FRI) consensus definition, which is based on specific diagnostic criteria, has not been fully validated in clinical studies. We aimed to determine the diagnostic performance of the criteria of the FRI consensus definition and evaluated the effect of the combination of certain suggestive and confirmatory criteria on the diagnostic performance. A multicenter, multi-national, retrospective cohort study was performed. Patients were subdivided into an FRI or a control group, according to the treatment they received and the recommendations from a multidisciplinary team ('intention to treat'). Exclusion criteria were patients with an FRI diagnosed outside the study period, patients younger than 18 years of age, patients with pathological fractures or patients with fractures of the skull, cervical, thoracic and lumbar spine. Minimum follow up for all patients was 18 months. Overall, 637 patients underwent revision surgery for suspicion of FRI. Of these, 480 patients were diagnosed with FRI, treated accordingly, and included in the FRI group. The other 157 patients were included in the control group. The presence of at least one confirmatory sign was associated with a sensitivity of 97.5%, a specificity of 100% and a high discriminatory value (AUROC 0.99, p < 0.001). The presence of a clinical confirmatory criterion or, if not present, at least one positive culture was associated with the highest diagnostic performance (sensitivity: 98.6%, specificity: 100%, AUROC: 0.99 (p < 0.001)). In the subgroup of patients without clinical confirmatory signs at presentation, specificities of at least 95% were found for the clinical suggestive signs of fever, wound drainage, local warmth and redness. The presence of at least one confirmatory criterion identifies the vast majority of patients with an FRI and was associated with an excellent diagnostic discriminatory value. Therefore, our study validates the confirmatory criteria of the FRI consensus definition. Infection is highly likely in case of the presence of a single positive culture with a virulent pathogen. When certain clinical suggestive signs (e.g., wound drainage) are observed (individually or in combination and even without a confirmatory criterion), it is more likely than not, that an infection is present.