This review highlights the recent advances using deep eutectic solvents (DESs), deep eutectic ionic liquids (DEILs), low-melting mixtures (LMMs) or low transition temperature mixtures (LTTMs) as green media as well as catalysts in organic reactions.

Low melting mixture of maltose–dimethylurea (DMU)–NH₄Cl was found to be an inexpensive, non-toxic, easily biodegradable and effective reaction medium in the catalyst-free synthesis of quinazoline derivatives. This simple and efficient method furnished the corresponding quinazolines in high yields via one-pot three-component reaction of 2-aminoaryl ketones, aldehyde, and ammonium acetate under aerobic oxidation conditions.

A covalent organic framework immobilized Cu catalyst was prepared and applied for synthesis of N-arylated products by Chan–Lam coupling reaction of arylboronic acids with various amines.